Adrenalin injection solution 1mg/1ml of cardiac resuscitation, anaphylaxis emergency (2 blisters x 5 tubes)

Dosage form Adrenaline
Specifications Anaphylaxis, bronchial asthma
Ingredient High blood pressure

Ingredient

Composition information	Content
Adrenaline	1mg

Uses

Indications

Adrenalin is designated in the following cases:

Heart lung resuscitation.

Anaphylaxis and anaphylaxis (with system vasodilation and low cardiac supply).

Indications and use of adrenalin must be done by experienced doctors.

Pharmacokic

Adrenalin is a direct effect on the sympathetic system, stimulating both alpha receptors and beta receptors, but acting on beta receptors is stronger than the alpha receptor. On the heart, Adrenalin works to increase frequency and increase the force contractions, increase the systolic vol

On the respiratory apparatus, Adrenalin stimulates mild respiration, causes strong bronchodilions, but makes bronchial secretions more.

On the digestive system, Adrenalin causes a decrease in tone and reduces the excretion of the intestine, increasing the blood flow.

On the urinary - genital system, Adrenalin sharply reduces the blood flow of the kidneys (may be up to 40%), but the glomerular filtration level is less changing, reducing the bladder tone but increases the muscle tone of smooth muscle, can lead to difficulty.

Adrenalin inhibits the uterine contractions of pregnant women.

On metabolic, adrenalin causes insulin secretion, glucagon secretion and glycogen resolution increases, leading to hyperglycemia, increasing the activity of renin, increasing freedom of fatty acids and potassium in plasma.

pharmacokinetics

Most adrenalin in the circulation are inactivated very quickly due to being imported into neuron cells, diffusion and enzymes in the liver and in tissues (catechol-o-methyltransferase and enzyme monoamine oxidase).

Metabolic products are excreted in urine.

Before taking Adrenalin injection solution 1mg/1ml of cardiac resuscitation, anaphylaxis emergency (2 blisters x 5 tubes)

How to use

Injection subcutaneously or intramuscularly.

Dosage

normal dose 1mg/time, maximum 2mg/24h.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Due to the harmful effects of Adrenalin exists very short because Adrenalin is durable very quickly in the body, the treatment of poisoning reactions in patients sensitive to drugs or due to overdose is mainly supportive treatment.

Injecting the drug has the effect of alpha blockers (phentolamin), then the injecting drug has a beta blocker (propranolol) to combat the effect of adrenalin's vasodilation and arrhythmic effects. Glycerin trinitrate can be used.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Adrenalin injection solution, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: headache, fatigue, sweat.

cardiovascular: tachycardia, hypertension, suspense.

nerve: Run, anxiety, dizziness.

digestive: secretion of saliva.

Uncommon, 1/1000

Cardiovascular: ventricular arrhythmia.

digestive: poor appetite, nausea, vomiting. nerve: Fear, restlessness, insomnia, easy to stimulate.

Genital urinary: difficulty, urination.

Respiratory: Difficulty breathing.

Rare, ADR

Cardiovascular: cerebral hemorrhage, pulmonary edema (due to hypertension), mail (due to vasoconstriction), arrhythmia, angina, hypotension, dizziness dizziness, fainting, cardiac arrest, tissue necrosis (due to adrenalin escaping from blood vessels when injected).

nerve: confusion, mental disorders.

Metabolic: Metabolic disorders, especially metabolism of glucose.

When encountering side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Contraindicated

Adrenalin injection solution is contraindicated in the following cases:

Patients with anesthesia with cyclopropan, Halothan or Halothan group anesthesia because they can cause ventricular vibration.

People with hyperthyroidism have not been treated stably.

Patients with severe cardiovascular disease, hypertension.

Patients with obstruction of urination.

Patients with narrow -angle glaucoma, patients are at risk of closed -angle glaucoma.

Precautions when taking drugs

Absolutely prohibited Adrenalin injection has not been diluted into the vein.

Patients are too sensitive to Adrenalin, especially people with hyperthyroidism.

Patients with cardiovascular disease (myocardial ischemia, dysliages or tachycardia, obstructive blood vessels (atherosclerosis, hypertension, aneurysm).

Patients with diabetes or people with narrow -angle glaucoma.

Patients are using cardiac glycosides, quinidine, antidepressants.

Pregnant women: Adrenalin passes through the placenta and in the cycle of the fetus in very small amounts. It is thought that it has the effect of causing fetal deformities in humans.

Lactating women: Adrenalin is considered safe for nursing mothers.

The impact of drugs when driving and operating machinery: No document.

Drug interaction

Adrenalin and beta blockers

Adrenalin's hypertension effects significantly increased in patients using unsatisfactory beta blockers like propranolol. There may be significant hypertension reactions or a significant, life -threatening heart rate.

Adrenalin and Monoamine inhibitors (Mao)

Adrenalin's hypertension effect may not change or only change less in patients who use Mao inhibitors.

Adrenalin and anesthesia

Patients with anesthesia by volatile anesthesia (cyclopropan, enfluran, halothan, isofluran, fluoroxen, methoxyfluran, diethyl ether) are at risk of arrhythmia if adrenalin, unless very small doses.

Adrenalin and alkaloids of Vayowolfia

When there are alkaloids of Vayowolfia, the hypertension effect of Adrenalin slightly increases.

Adrenalin and three -round antidepressants

Patients treated with three -ring antidepressants have a very strong response to adrenalin injection (hypertension, arrhythmia ...). Even on -site anesthetic with adrenlin should not be used for these patients.

Storage

Leave a cool place, avoid light, temperatures below 30 ° C.

To be out of reach of children.

Other drugs

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