AGBACTAM 1G Mekophar medicine supports the treatment of respiratory infections (2 blisters x 7 tablets)

Dosage form Box of 2 blisters x 7 tablets
Specifications Amoxicillin, clavulanic acid
Ingredient Mekophar

Ingredient

Composition information	Content
Amoxicillin	875mg
Clavulanic acid	125mg

Uses

Indications

Agbactam 1g medicine for treatment in a short time the following cases of infection:

Upper respiratory infections: tonsillitis, sinusitis, otitis media have been treated with conventional antibiotics but does not decrease.

Lower respiratory infections by H. Influenzae and Branhamella Catnrhalis, Beta -lactamase: Acute and chronic bronchitis, pneumonia - Bronchial.

Heavy -genital tract infections by E. coli, Klebsiella and Enerobacter produce beta -lactamase: cystitis, urethritis, pyelonephritis (female genital tract infections).

Skin infections and soft tissue: pimples, abscesses, wound infections.

Bone and joint infections: Bone inflammation.

Dental infections: tooth abscess.

Other infections: Obstetrics and gynecology, abdominal cavity.

Pharmacy

1G 1G AUGBactam is an antibiotic with wide antibacterial spectrum. The combination of amoxicilin with clavulanic acid in AGBactam 1G helps amoxicillin not destroyed by beta-lactamase, and expand the antibacterial spectrum of amoxicillin effectively to many bacteria that have resisted amoxicillin, other penicilins and cephalosporins such as:

Gram -positive bacteria: Streptococcus Faecalis, Streptococcus Pneumoniae, Streptococcus Pyogenes, Streptococcus Viridans, Staphylococcus aureus, Corynebacterium, Bacillus anthracis, Listeria monocytogenes Peptococcus, peptostreptoccus.

Gram -negative bacteria: Haemophilus Influenzae, Escherichia Coli, Proteus Mirabilis, Proteus vulgaris, Klebsiella, Salmonella, Shigella, Bordetella, Neisseria Gonorrhoeea, Nisisseria Meningitidis, Vibrio Cholaee, Cholerae,, Cholriae Pasteurella Multocida, Bacteroides including B.fragilis.

pharmacokinetics

amoxicillin and clavulanic acid are easily absorbed by oral. The concentration of these 2 substances in serum reaches up to 1-2 hours of medication. Amoxicillin's oral bioactivity is 90% and of Clavulanic acid is 75%.

The half-life of amoxicillin in serum is about 1-2 hours and of Clavulanic acid about 1 hour. 55 - 70% amoxicillin and 30-40% Clavulanic acid are discharged through urine in the form of unchanged.

Before taking AGBACTAM 1G Mekophar medicine supports the treatment of respiratory infections (2 blisters x 7 tablets)

How to use

as directed by the physician.

Dosage

Dosage is often used for adults and children> 12 years old

Severe infections: 1 tablet, 12 hours/time.

It is not recommended to use AGBactam 1g for children 12 years old and younger.

Should take the medicine at the beginning of the meal to minimize the phenomenon of non -tolerated drugs in the stomach - intestines.

Treatment must not exceed 14 days without examination.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

However, general reactions occur depending on the hypersensitivity of each individual.

The risk is definitely increased by potassium when taking very high doses because clavulanic acid is used in the form of potassium salt. Can use the method of hemolysis so that the drug is from the circulatory system.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using AGBACTAM 1G, you may experience unwanted effects (ADR).Common

diarrhea, rash, itching.

rarely

Incretion, nausea, vomiting, hepatitis and jaundice, transaminase.

rarely

Anaphylaxis reaction, Quincke edema, platelet reduction, leukopenia, hemolytic anemia, fake colitis, Stevens-Johnson syndrome, diverse erythema, peeling dermatitis, epidermal necrosis due to poisoning, interstitial nephritis.

Notify the doctor with unwanted effects when using the drug.

Instructions on how to handle ADR

Can reduce the side effects of the drug by reducing the dose.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

1g 1g AUGBactam medicine in the following cases:

Sensitive to the beta-lactam group (penicillin, cephalosporin).

People with a history of jaundice or liver disorders due to the use of amoxicillin, clavulanate or penicillin.

Caution when using

for patients with manifestations of liver dysfunction, kidney failure.

The ability to drive and operate machinery

The drug has almost no effect on driving and operating machinery. However, there are also a few reports on the risk of dizziness, so the doctor may depend on the specific case that is recommended or not recommended for patients to use drugs when driving and operating machinery.

Pregnancy

Avoid using AGBACTAM 1G for pregnant women especially in the first 3 months, except for the necessary case prescribed by the doctor.

Breastfeeding period

During breastfeeding can use AGBABactam. The drug is not harmful to breastfed children unless there is a risk of sensitivity due to a very small amount of medicine in milk.

Medicinal interaction

Popular drugs that prolong bleeding time and prothrombin time. Therefore, it is necessary to be careful for those who are treated with anticoagulants.

The drug can reduce the effectiveness of oral contraceptives, so it is necessary to notify the patient in advance.

Probenecid extends the excretion time of amoxicillin but does not affect the elimination of clavulanic acid.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Other drugs

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