Agicetam 400 Agimexpharm Treatment Treatment Symptoms (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Piracetam
Ingredient Muscle vibration, memory impairment, difficulty learning in children, chronic alcoholism, Alzheimer, tooth loss, dizziness

Ingredient

Composition information	Content
Piracetam	400mg

Uses

Indications

Agicetam 400 medicine belongs to the nerve -oriented drug group used in the following cases:

Treatment of dizziness symptoms. 927 patients with acute ischemic stroke shows progress on behavior after 12 weeks of treatment, especially in patients who initially had severe neurological symptoms that were used for the first 7 hours after the stroke). It is important to pay attention to the age and severity of the disaster at the beginning are the most important factors for priesting the ability to survive the stroke of acute anemia stroke. In children treatment support difficult to read. Specific effects as well as its acting mechanism.

Piracetam affects some neurotransmitters such as acetylcholin, noradrenalin, dopamin ... The drug can change a neurotransmitter and contribute to improving metabolic environment for good neurons to work well.

On experiments, Piracetam has a protective effect against metabolic disorders due to ischemia by increasing brain resistance to oxygen deficiency.

Piracetam increases the mobilization and use of glucose without depending on the supply of oxygen, facilitates the pentose path and maintains energy synthesis in the brain.

The drug also works to increase dopamine release, which works well on memory formation.

Piracetam has no effect on sleep, sedation, resuscitation, pain relief.

Piracetam reduces the ability to converge platelet and in case of abnormal erythrocytes, the drug can cause red blood cells to restore deformation and ability to pass through capillaries. The drug has anti -vibration effect.

pharmacokinetic

absorption

Piracetam used by oral is absorbed quickly and almost entirely in the gastrointestinal tract. Birth nearly 100%. Absorption of drugs does not change during long -term treatment.

Distribution

The distribution volume is about 0.6L/kg. Piracetam absorbed into all tissues and can pass through the bloody brain barrier, placenta and even the membranes used in the renal roses. Piracetam is not attached to plasma proteins.

Elimination

is excreted through the kidneys in the form of intact, the kidney's piracetam clearance coefficient in normal people is 86ml/min, 30 hours after drinking, more than 95% of the drug is waste in urine. In people with kidney failure, the selling time increases.

Before taking Agicetam 400 Agimexpharm Treatment Treatment Symptoms (10 blisters x 10 tablets)

How to use

Take the tablet with a glass of water. Can be taken with food or not.

Dosage

The usual dose is 30 - 160mg/kg/day, depending on the indications. The drug is used injected or taken, divided evenly 2 times or 3-4 times. Take medication if the patient can drink. It is also possible to use injection to drink if you have to stop using the injection form. In severe cases, the dose can be increased to 12g/day and use by intravenous line.

In addition, depending on the different treatment purposes will have other doses such as:

Long -term treatment of physical mental syndrome in the elderly: 1.2 - 2.4g a day, depending on the case. The dose may be high to 4.8g/day in the first weeks.

Alcoholic treatment: 12g a day during the first time of alcohol. Maintenance treatment: Take 2.4g/day.

Awareness decline after brain injury (with dizziness or no): The initial dose is 9 - 12g/day, the maintenance dose is 2.4g of medicine, taken at least for at least three weeks.

sickle blood cell anemia: 160mg/kg/day, divided equally into 4 times.

Treatment of muscle vibration, piracetam is used at a dose of 7.2 g/day, divided into 2-3 times. Depending on the response, every 3-4 days, an increase of 4.8g daily to a maximum dose of 20g/day. After reaching the optimal dose of Piracetam, it is advisable to find a way to reduce the dose of the attached drugs.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? There is no need for special measures to overdose.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Agicetam 400, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Body: tired.

Digestive: Nausea, vomiting, diarrhea, abdominal pain, abdominal distention.

Neurological: restlessness, ease of agitation, headache, insomnia, sleeping.

Uncommon, 1/1000

Body: Dizziness.

Neurology: Run, sexual stimulation.

Instructions on how to handle ADR

Can reduce the side effects of the drug by reducing the dose.

Warnings

Before using the drug, you need to read the instructions carefully and refer to the information below.

Contraindicated

Agicetam 400mg drug contraindicated in the following cases:

Patients with severe renal failure (creatinine clearance coefficient below 20ml/minute).

People suffering from Huntington.

Patients with liver failure.

Precautions when used

Because Piracetam is discharged through the kidneys, the half -life of the drug increases directly to the level of renal failure and creatinine clearance. It is necessary to be very cautious when taking the drug for patients with renal failure. Need to monitor kidney function in these patients and elderly patients.

When the clearing coefficient of creatinine is below 60ml/minute or when the serum creatinine is over 1.25mg/100ml, the dose adjustment must be adjusted:

Creatinine clearance coefficient is 60 - 40ml/min, serum creatinine is 1.25 - 1.7mg/100ml (half -life of piracetam is more than twice as long): only 1/2 of normal dose.

Creatinine clearance coefficient is 40 - 20ml/min, serum creatinine is 1.7 - 3.0mg/100 ml (half -life of piracetam is 25 - 42 hours): Use 1/4 normal dose.

Avoid stopping the sudden drug in patients with muscle vibration due to the risk of seizures.

Precautions in patients with stomach ulcers, a history of stroke due to bleeding, use with drugs that cause bleeding due to increased risk of bleeding.

Precautions in major surgery due to potential coagulation disorders.

The ability to drive and operate machinery

The drug has almost no effect on driving and operating machinery. However, there are also a few reports on the risk of dizziness, so the doctor may depend on the specific case that is recommended or not recommended for patients to use drugs when driving and operating machinery.

Pregnancy

Agicetam 400 medicine with the main component of Piracetam can be through the placenta. Do not use this medication for pregnant people.

Breastfeeding period

Do not use Agicetam 400 with the main ingredient Piracetam for nursing mothers.

Medicinal interaction

can still continue the classic method of alcoholic (vitamins and sedatives) in the case of a person with vitamin deficiency or strong agitation.

There has been a case of interaction between piracetam and thyroid essence when used simultaneously: confusion, stimulation and sleep disorders.

In a patient, prothrombin time has been stabilized by warfarin when using piracetam.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

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