Agifivit Agimexpharm and treatment of iron deficiency anemia, folie acid deficiency (10 blisters x 10 tablets)

Dosage form Tablet
Specifications Box of 10 blisters x 10 tablets
Ingredient Ferrous fumarate, folic acid
Indication Fatigue, iron deficiency anemia
Contraindication Excess iron

Ingredient

Composition information	Content
Ferrous Fumarate	200mg
Acid folic	1mg

Uses

indications

Agifivit 200 mg Agimex 10x10 is indicated in cases of prevention and treatment of iron deficiency anemia, folie deficiency in the following cases:

Pregnant and lactating women, menstruation, menstrual regulation.

Cases of increased hematopoietic demand such as: after trauma, surgery, gastric gastric cutting, malnutrition syndrome, serious recovery stage.

Daily diet does not provide adequate iron, folic acid.

Pharmacokological

iron Fumarat

is a form of organic iron easily absorbed into the body. Fe2+ found in fumarat iron plays an important role in creating hemoglobin, myoglobin and cytochrom respiratory enzymes C. Fe2+ deficiency, red blood cells cannot be formed, the absorption process O2 and CO2 is seriously affected.

Folic acid

As a vitamin of Group B in the body, it is reduced to tetrahydrofolate which is the coenzyme of many metabolic processes including the synthesis of nucleotides with purin or pyrimidine nucleus; Therefore, it affects DNA synthesis. When vitamin C, folic acid is converted into leucovorin is essential for DNA and RNA synthesis.

Folic acid is an indispensable factor for nucleoprotein synthesis and normal red blood cells, folic acid deficiency that cause huge red blood cell anemia like anemia due to vitamin B12 deficiency. Folic acid also participates in some amino acid changes, in format formation and use.

Combining folic acid with iron to use for pregnant women to prevent huge red blood cell anemia. This combination has a good effect on anemia during pregnancy than using a single substance.

pharmacokinetic

iron

Normal iron is absorbed in the duodenum and close head. A normal person does not lack iron, absorbs about 0.5 - 1 mg of elemental iron daily. Iron absorption increases when low iron reserves or increased iron demand. The entire iron absorption increases to 1 - 2 mg/day in normal menstrual periods and can increase to 3-4 mg/day in pregnant women. Young children and teenagers also need to increase iron in the period of strong development.

iron absorption is reduced when there are chelate substances or complex agents in the intestine and increase when there is hydrochloric and vitamin. Therefore, sometimes iron is used in combination with vitamin C.

Iron is stored in the body in two forms: ferritin and hemosiderin. About 90% of iron put into the body is discharged through feces.

iron absorption depends on the amount of iron reserves, especially ferritin, in the intestinal mucosa and on the body's red blood cell speed.

Folic acid

Folic acid released rapidly in the stomach and absorbed mainly at the beginning of the small intestine. Folic acid in normal diet is absorbed very quickly and distributed in tissues in the body. The drug is stored mainly in the liver and is actively focused in cerebrospinal fluid. Every day about 4 - 5 mcg excreted through urine. Drink high -dose folic acid causes vitamins eliminated through urine to increase in proportion. Folic acid passes through the placenta and is in breast milk.

Before taking Agifivit Agimexpharm and treatment of iron deficiency anemia, folie acid deficiency (10 blisters x 10 tablets)

How to use

oral drugs. Take medicine with lots of water.

Dosage

1 tablet daily before eating 1 hour or after 2 hours, or as directed by the doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Symptoms of overdose

Abdominal pain, nausea, vomiting, diarrhea with blood, dehydration, acidic and shock with chicken sleep.

Overdose

First: gastrointestinals immediately with milk (or carbonate solution) or using chelate, the most specific is Deferoxamine. For shock and acidic abnormalities are treated in the usual way. Severe cases should be taken immediately to medical facilities for timely management.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Agifivit 200 mg Agimex 10x10, you may experience unwanted effects (ADR).

Itching, rash, urticaria. Sometimes digestive disorders (abdominal pain, nausea, vomiting, constipation). The feces may be black due to drugs.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Agifivit 200 mg Agimex 10x10 contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

iron excess. iron infection.

Anemia hemolysis.

Red blood cell disease.

Precautions when using

People with normal amount of iron in the blood to avoid prolonged medication.

Stop using drugs if not tolerated.

Children under 12 years: Do not use tablets, capsules. Only use drops or syrup (suction through tube).

Avoid taking medicine with tea water reduces iron absorption.

The drug can cause black or gray feces.

The ability to drive and operate machinery

The ability to drive or operate machinery is not affected when taking medicine.

Pregnancy

drugs used for pregnant women during anemia due to iron deficiency and folic acid.

Breastfeeding period

The drug is used for breastfeeding women.

Medicinal interaction

Penicillamin absorption, tetracyclin, levodopa, methyldopa, quinolones, thyroid hormones and zinc salts if shared.

antacids such as calcium carbonate, sodium carbonate, and magnesium trisilicat; Tea can reduce iron absorption if used at the same time.

If using folic acid to supplement folat may be caused by anti -convulsions, the concentration of anti -seizures in serum may be reduced.

cotrimoxazol reduces the treatment of huge red blood cell anemia of folic acid.

Oral contraceptives reduce metabolism of folat, causing folat and vitamin B12.

Storage

temperature below 30 ° C, avoid moisture and light.

Other drugs

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