Agimfast 180 Agimexpharm Treatment of allergic rhinitis, indefinite urticaria (2 blisters x 10 tablets)

Dosage form Film bag tablets
Specifications Box of 2 blisters x 10 tablets
Ingredient Fexofenadin hydrochlorid
Indication Allergic rhinitis, urticaria, contact dermatitis, stuffy nose

Ingredient

Composition information	Content
Fexofenadin hydrochlorid	180mg

Uses

Indications

Agimfast drugs are indicated in cases of treatment of allergic rhinitis symptoms such as sneezing, runny nose, nasal back, tilting palate and throat, itchy eyes and watery eyes, chronic urticaria.

Pharmacokological

Fexofenadin is a second -generation antihistamine drug, with specific antagonistic and selective effects on peripheral H1 receptors.

The drug is a metabolic substance that is active of terfenadin but no longer toxic to the heart due to not inhibiting potassium channel associated with myocardial cell red.

Fexofenadin has no significant effect on acetylcholine antagonism, dopamine antagonism and has no effect of inhibiting receptors of Alpha1 - or beta -adrenergic. At the treatment dose, the drug does not cause sleep or affects the central nervous system.

The drug has a fast and prolonged effect due to the slow -attached drug into the H1 receptor, forming a sustainable complex and separating slowly.

pharmacokinetics

Good absorption drug when used oral. After taking 1 60mg tablet, the peak concentration in the blood is about 142 nanogam/ml, achieved after 2 to 3 hours. Food reduces the peak concentration in plasma by about 17% but does not slow down the time to reach the peak concentration of the drug.

The ratio of the plasma protein of the drug is 60 to 70% mainly with albumin and alpha1 - Glycoprotein acid. The distribution volume is 5.4 - 5.8 liters/kg. It is unclear whether the drug is through the placenta or excretion in breast milk, but when using terfenadin has detected fexofenadin is the metabolic substance of terfenadin in breast milk. Fexofenadin does not pass the brain barrier.

approximately 5% of the dose of the drug is metabolized. About 0.5 to 1.5% are metabolized in the liver thanks to the cytochrom P450 enzyme system into non -active substances. 3.5% are converted into methyl ester derivatives, mainly thanks to the bacterial system.

Half of Fexofenadin elimination is about 14.4 hours, longer in renal failure. The drug is excreted mainly in feces (about 80%), 11 to 12% of the dose is eliminated in the urine in the form of constant.

Before taking Agimfast 180 Agimexpharm Treatment of allergic rhinitis, indefinite urticaria (2 blisters x 10 tablets)

How to use

oral tablets.

Dosage

Adults and children ≥ 12 years: Take 1 capsule/time x 2 times/day.

The starting dose for people with kidney failure is only 1 tablet/24 hours.

The elderly and patients with liver failure do not need to reduce the dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? However, drowsiness, dizziness, dry mouth have been reported.

Handling: Using conventional measures to remove the drug that has not been absorbed in the digestive tract. Support support and treatment.

Hemolysis reduces the concentration of drugs in the blood (1.7%). There is no specific antidote.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

The unwanted effects of the drug are not affected by the dosage, age, gender and race of the patient.

Common: Sleep, fatigue, headache, insomnia, dizziness; nausea, indigestion; Virus infection (colds, flu), dysmenorrhea, upper respiratory infections, itchy throat, cough, fever, otitis media, sinusitis, back pain.

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Agimfast drugs contraindicated in the following cases:

Hypersensitivity to any ingredients of the drug.

Not for children under 12 years old.

Precautions when using

should be very cautious when taking medication for patients in cases of older people, patients with liver or kidney failure.

Be careful to monitor (patients or drugs) when using fexofenadin for people who are at risk of cardiovascular or have a long-lasting Q-T interval.

Do not use any other antihistamine drugs while using fexofenadin.

Use drugs for women during pregnancy and lactation

Pregnancy

Because there is no complete research on pregnant women, only fexofenadin is used for pregnant women when the maternal benefits are superior to the risk of the fetus.

Breastfeeding period

It is not clear whether the drug is excreted in milk, so it is necessary to be cautious when using fexofenadin for breastfeeding women.

The effect of the drug on the ability to drive and operate machinery

Although Fexofenadin is less drowsy, still need to be cautious when driving or operating machinery.

Drug interaction

erythromycin and ketoconazole increases the concentration and area under the fexofenadin -level concentration curve in the blood, the mechanism may be due to increased absorption and reduction of this drug elimination. However, the interaction does not mean clinically.

Antacomicisted with aluminum, Magnesi if used simultaneously with fexofenadin will reduce the absorption of the drug, so they must use these drugs about 2 hours apart.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.