Alfa-lipogamma 600 Oral Work supports the treatment of diabetes with diabetes (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Thioctic acid
Ingredient Multiple nerve inflammation

Ingredient

Composition informationContent
Thioctic acid600mg

Uses

indications

Alfa-lipogamma 600 oral drugs are indicated in the following cases:

  • Treatment of abnormalities in diabetic polygonal disease.

    Hypergathy growth in diabetes leads to glucose accumulation in base proteins in blood vessels and forming substances called the final products of the glycate process.

    This process leads to a decrease in internal blood flow and hypoxemia/hypoglycemia, combined with the increase in free oxygen production, which can be identified in peripheral nerves like when impaired antioxidants like glutathione.

    In mice studies, thioctic acid interacts with biochemical processes caused by experimental diabetes mice caused by streptozocin through a decrease in the formation of the final products of the glycate process, improving the neurological blood flow, increasing the antioxidant level of glutathione and antioxidants for free oxygen in diabetic oxygen.

    The observed results under the experimental conditions show that the function of peripheral nerve may be improved by the thioctic acid. This is related to sensory disorders in diabetic polygonary inflammation can be expressed as sensory disorders, paresthesia such as heat, pain, numbness, and sensations of cows.

    Supplementing the previous clinical results in the treatment of symptoms of diabetes with diabetes with thioctic acid, a central study, controlled to placebo in 1995, showing the beneficial effects of Thioctic acid on hot, intense, numb and painful symptoms.

    pharmacokinetics

    absorption:

    Acid Thioctic (alpha-lipoic acid) is quickly absorbed after taken. Due to significant first metabolic effects, absolute bioavailability (compared to intravenous lines) of thioctic acid is approximately 20%.

    Relative bioavailability of thioctic acid when used in solid form is 60% higher than oral solution.

    Maximum plasma concentrations approximately 4 μg/ml are measured about 0.5 hours after taking 600 mg of thioctic acid.

    Distribution:

    Quickly distributed drugs into the tissues in the body.

    Metabolism:

    Biological changes occur mainly due to oxidation of sequence (beta-oxidation) and/or S-methylation of isotope.

    Era:

    With the ability to quickly distribute into the tissue in the body, the semi -cancellation time in the plasma of the thioctic acid in humans is approximately 25 minutes.

    Using radioactive marking methods in animal tests (mice, dogs) shows that the excretory sugar is mainly through the kidney, most (80–90%) in the form of metabolites.

    Only a small amount of unchanged substances is found in urine.

    • Before taking Alfa-lipogamma 600 Oral Work supports the treatment of diabetes with diabetes (3 blisters x 10 tablets)

    How to use

    Alfa-lipogamma 600 oral drugs for oral use.

    The drug should be taken in whole with a sufficient amount of water when hungry. When taking the drug simultaneously with food can reduce absorption. Therefore, it is advisable to take the drug 30 minutes before breakfast, especially in patients who have the time to empty the stomach for a long time.

    Due to diabetic neuritis is a chronic disease, long -term treatment may be required.

    The basic foundation of the treatment of diabetes is the optimal blood sugar control.

    Dosage

    For cases of sensory disorders associated with diabetic neuritis in adults, the daily dose is recommended for adults: 1 tablet x 1 time/day.

    In the case of serious sensory disorders, the infusion therapy with Thioctic acid can be conducted first.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

    Treatment of total seizures, lactic acid infections and other life -threatening consequences of poisoning should be done with supportive care principles and need symptomatic treatment.

    Benefits of hemorrhage and peritoneal fertilizer or filtering methods to eliminate alpha-lipoic acid do not give sure results.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using Alfa-Lipogamma 600 Oral, you may experience unwanted effects (ADR).

    Common, ADR> 1/100:

  • No report.

    • Uncommon, 1/1000

  • No report.

    • Rare, 1/10000

  • No report.

    • Very rare, ADR

  • Digestive: Nausea, vomiting, stomach pain, diarrhea.

    • Allergic reactions such as rash, urticaria, itching. nerve: Change and/or taste disorders. Metabolic: Hypoglycemia.

    Not determined frequency:

  • Autotological insulin syndrome (hormonal hormone disorders of blood glucose has significantly reduced blood sugar levels).

    • Instructions on how to handle ADR:

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    Alfa-lipogamma 600 oral drugs are contraindicated in the following cases:

  • Hypersensitivity to the thioctic acid or any ingredient of the drug.
  • Children and teenagers.

    • Caution when using

    Patients with genetic antigen genotype people are easily developed with autoimmune insulin syndrome (disorders in blood glucose regulating hormones with significant decreased blood sugar levels) when treated with thioctic acid.

    Patients with genetic, non-absorbing fructose-gh-glucose-galactose or enzyme-deficiency of Saccharase-Isomaltase should not be taken.

    The ability to drive and operate machinery

    Because the drug has unwanted effects such as hypoglycemia, dizziness, sweating, headache, visual change, should be cautious when using the drug while driving and operating machinery.

    Pregnancy

    There is no data on drug use in pregnant women, only drugs should only be used if the benefits are out of risk.

    Breastfeeding period

    Do not know if the acidCtic acid is secreted into breast milk or not.

    Drug interactions

    loss of effect of cisplatin when used simultaneously with exam acid.

    Thioctic acid is a substance that can be complex with metal ions. Therefore, the drug should not be used simultaneously with metal compounds (such as iron, magnesium, dairy products containing calcium). If the drug is used daily 30 minutes before breakfast, the products containing iron, Magnesi can be used at noon or afternoon.

    Hypoglycemic effects may occur when combined with insulin or other diabetes medications. Therefore, it is necessary to monitor blood sugar closely, especially in the early stages of treatment with thioctic acid.

    In special cases, reducing insulin dose or oral diabetes treatment drugs is necessary to prevent signs of hypoglycemia.

    Storage

    Store less than 30ºC, avoid light and moisture.

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