Ame Bismo 262mg OPV medicine reduces stomach discomfort, indigestion, heartburn (6 blisters x 10 tablets)

Dosage form Box of 6 blisters x 10 tablets
Specifications Bismuth subsalicylat
Ingredient OPV

Ingredient

Composition information	Content
Bismuth subsalicylat	262mg

Uses

indicated

Reducing unpleasant symptoms in the stomach, indigestion, heartburn and nausea. honey, reduced endogenous prostaglandin and bicarbonate.

Bismuth Subsalicylate reduces the number of times, firms, and normates the movement of liquid through the mechanism of anti -secretion, bacterial toxins of bacteria, and showing antibacterial activity in patients with diarrhea.

Dynamic pharmacokinetics

bismuth subsalicylate are transformed into bismuth carbonate and sodium salicylate in the small intestine. Oral bioavailability of Bismuth Subsalicylate is very low. Bismuth's distribution capacity in the tissue of the human body is very small. Although Bismuth is also excreted through bile, the renal clearing is the path of excretion of Bismuth. The rest of the drug is excreted in feces in the form of insoluble bismuth salt. After taking the maximum daily recommended dose for adults, the average biological destruction time is about 33 hours and the peak concentration of Bismuth in plasma is below 35 ppb.

Salicylate absorbs through the intestine and quickly distributed into the body's tissues. The peak concentration in plasma after the maximum daily dose is about 110 micrograms/ml. Salicylate is quickly excreted from the body and the average biological destruction time is about 4-5.5 hours.

Before taking Ame Bismo 262mg OPV medicine reduces stomach discomfort, indigestion, heartburn (6 blisters x 10 tablets)

How to use

Chewing pills, do not use more than 2 days.

Dosage

Adults and children aged 12 and older: 2 capsules/time.

Can be used repeatedly on 1/2 - 1 hour if needed, up to 8 doses in 24 hours. If the symptoms are still there, need to see a doctor.

Because diarrhea can cause dehydration, need to drink enough water to rehydration.

What to do when overdose?

How to handle : Causes vomiting or gastric lavage, using activated carbon. Transfusion, dialysis, peritoneal or blood transfusion is necessary for serious overdose.

Monitor Salicylate concentration in serum until the drug concentration decreases below the poisoning level. Monitoring and treating the survival functions, monitoring the phenomenon of pulmonary edema and convulsions for appropriate treatment.

What to do when you forget 1 dose?

Side Effects

Common, ADR> 1/100: Black dyeing or tongue, coloring tooth color (recovery).

Uncommon, 1/1000

Rare, ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Hypersensitivity to Bismuth Subsalicylate or any component of the drug.

Be cautious when using

Ambismo contains salicylate, if taking the drug with aspirin that appears tinnitus, should stop taking the drug.

Ambismo does not contain aspirin, but if you've ever been allergic to aspirin or with other salicylate does not contain aspirin, you should not take the drug because there may be unwanted reactions. If diarrhea has a high fever or lasts more than 2 days, see a doctor. Do not use this medication to treat nausea and vomiting for children and teenagers who are suffering from chickenpox or flu or recover from the two diseases.

If there is still nausea or vomiting, it is necessary to see a doctor because these symptoms may be an early sign of Reye syndrome, a serious but rare scene.

Patients with renal failure.

Severe liver disease can cause bismuth accumulation.

The effect of the drug on driving and operating machinery

No report.

Using drugs for women during pregnancy and lactation

There is no adequate data on the use of drugs in pregnant women.

Animal studies are not enough for pregnancy, the development of embryos/fetuses, childbirth and postpartum development. Unknown risks for humans.

Do not use bismuth subsalicylate during pregnancy and breastfeeding unless really necessary.

Medicinal interaction

anticoagulant drugs: Salicylate salt (Bismuth Subsalicylate) may increase the risk of bleeding when used simultaneously with anticoagulant drugs. Need to monitor the anticoagulant treatment, adjust the anticoagulant dose when necessary.

Diabetes treatment: Hypoglycemic effects can be increased when used simultaneously with salicylate salt. Need to be careful when using combination.

ciprofloxacin: Bismuth subsalicylate reduces the peak concentration in plasma and auc of ciprofloxacin.

doxycyclin: bismuth subsalicylate reduces the absorption of Doxycycline. Avoid using bismuth subsalicylate to self -treat for tourists who are using doxycyclin to prevent malaria.

Storage

At temperatures below 30 ° C, in a dry place, avoiding light.

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