Ameflu Multi-Symtom Relief OPV Smor Smy Tree Treatment of flu symptoms (60ml)

Dosage form Bottle x 60ml
Specifications Acetaminophen, phenylephrine, dextromethorphan, chlorpheniramine
Ingredient Sore throat, allergic rhinitis, cough, fever, body aches, nasal congestion

Ingredient

Composition information	Content
Acetaminophen	160mg
Phenylephrine	2.5mg
Dextromethorphan	5mg
Chlorpheniramine	1mg

Uses

Indications

temporarily reduce common cold symptoms: Mild pain, headache, sore throat, nasal congestion (nasal congestion), cough, nasal flow, sneezing and fever.

Pharmacokology

There is no information because the preparation has many active ingredients.

pharmacokinetics

There is no information because the preparation has many active ingredients.

Before taking Ameflu Multi-Symtom Relief OPV Smor Smy Tree Treatment of flu symptoms (60ml)

This drug is only used as prescribed by a doctor.

How to use

Take oral use.

Dosage

Children

Children from 6 to 11 years old

Take 2 teaspoons (10ml) every 4 hours. Do not use more than 10 teaspoons (50ml)/24 hours.

Children from 4 to 5 years old

As directed by the doctor or take 1 teaspoon (5ml) every 4 hours. Do not use more than 5 teaspoons (25ml)/24 hours.

Children under 4 years old

consult a doctor.

What to do when overdose?

acetaminophen

Symptoms: Nausea, vomiting and abdominal pain (occurring within 24 hours after drinking). After 24 hours, symptoms may include right -lowered pain, often indicating the growth of liver necrosis. Liver damage is most about 3-4 days after taking the drug overdose and can lead to brain disease, hemorrhage, hypoglycemia, brain edema and death.

Treatment: Treatment depends on plasma concentrations. Acetylcystein protects the liver if used for about 24 hours from the overdose of acetaminophen (most effective if used for about 8 hours). The first dose is 140mg/kg (loading dose), then giving 17 more doses, each dose of 70mg/kg 4 hours apart. Activated carbon or gastric wash can be done to reduce the absorption of acetaminophen.

phenylephrine hydrochloric

Symptoms: Hypertension, headache, convulsions, cerebral hemorrhage, chest drums, slow heart rate.

How to handle: symptomatic and supportive treatment.

dextromethorphan

Symptoms: Nausea, vomiting, drowsiness, blurred vision, eyeball, urination, numbness, hallucinations, loss of air conditioning, respiratory failure and convulsions.

How to handle: Support treatment and symptomatic treatment. Naloxon 2mg can be used in intravenously, repeated if necessary.

chlorpheniramin maleat

Symptoms:

Dosage of chlorpheniramin (chlorpheniramine) about 20 - 50mg/kg body weight.

Symptoms and overdose signs include sedation, naughty stimulation often central nervous system, mental disorder, seizures, apnea, convulsions, acetylcholine resistance, hypertonic reaction, cardiovascular collapse and arrhythmia.

How to handle:

Stomach or vomiting with ipecacuanha syrup. Then, for active carbon and bleach to limit absorption.

When experiencing hypotension and arrhythmia, it should be actively treated. It is possible to treat convulsions with intravenous diazepam or phenytoin intravenously. May have to be blood transfusion in heavy cases.

Pay special attention to liver, kidney, respiratory, heart, water and electrolyte.

In case of overdose, immediately contact the doctor or go to the nearest hospital.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Ameflu may experience some side effects:

Drugs can cause drowsiness.

Some cases of allergies to drugs rarely occur such as: rash, red skin, urticaria.

Other side effects can be nausea, vomiting, restlessness, headache , dizziness, stomach pain, tremor, mental change, mild fever, less appetite, jaundice, insomnia, rash, face, tongue, lips or sore throat, tiredness, dry mouth , urinary retention, neutrophils, blood cell reduction, hematuria, pale skin, pale skin, skin, skin Trembling, hallucinations, shortness of breath, arrhythmia, special stimulation in children.

The drug can cause excitement, especially in children.

Warnings

Contraindicated

AMEFLU drug is contraindicated in the following cases:

Patients are known to hypersensitivity to any ingredients of the drug.

Patients who are taking imao drugs (see drug interactions).

Patients with coronary artery disease and severe high blood pressure.

Lack of G6PD.

Patients with severe liver failure.

Narrow angle glaucoma.

Prostate hypertrophy.

Hen -asthma attacks.

Bladder obstruction.

respiratory failure.

Stomach - duodenal ulcer, pyloric stenosis - duodenum.

Be cautious when taking drugs

Caution and special warning when using drugs containing active ingredients Acetaminophen:

Doctors need to warn patients on signs of serious skin reactions such as Steven-Johnson syndrome (SJS), toxic skin necrosis syndrome (Ten), or Lyell syndrome, acute pustules syndrome (AGEP).

Serious side effects on the skin, although the incidence is not high but serious, even life-threatening including Steven-Johnson (SJS) syndrome, toxic skin necrosis syndrome: Toxic Epidermal Necrolysis (Ten) or Lyell syndrome, Extracurricular Syndrome Systemic Bodhisattva: Acute Generalized Exanthematous Pustulosis (AGEPSIS).

Symptoms of the above syndrome are described as follows

Steven - Johnson syndrome (SJS): is an allergy to puffiness, bullous puffiness around natural cavities: face, nose, mouth, ears, genitals and anus. In addition, it may be accompanied by high fever, pneumonia, liver and kidney dysfunction. Diagnosis of Steven-Johnson syndrome (SJS) when there are at least 2 naturally damaged cavities.

Poisoned skin syndrome (ten): is the most severe allergic drug, including:

Diverse lesions in the skin: measles rash, pink pink rash, roses or bulls, and damage quickly spread throughout the body.

Eye mucosa damage: corneal inflammation, pus conjunctivitis, corneal ulcer.

Damage to the gastrointestinal mucosa: stomatitis, mouth mucosa, pharyngeal ulcer, esophagus throat, stomach, intestines.

Damage to the mucosa of genital tract, urinary tract.

There are also serious systemic symptoms such as fever, gastrointestinal bleeding, pneumonia, glomerulonephritis, hepatitis ... high mortality rate 15 - 30%.

Excellent pustules syndrome (AGEP): Small sterile pustules arise on the spreading platform. Damage often appears in folds such as armpits, groin and face, then can spread the whole body. Systemic symptoms are often fever, neutral leukemia tests.

When detecting signs of rash on the first skin or any other hypersensitive reactions, patients need to stop using the drug. People who have had serious skin reactions caused by acetaminophen are not allowed to use the drug again and when they go to medical examination and treatment, they need to notify the medical staff on this issue.

Consult your doctor if you have a disease:

Liver disease, heart disease, high blood pressure, thyroid disease, diabetes.

Difficult to be hypertrophy.

Prolonged cough or chronic cough like cough due to asthma.

Excessive cough (mucus).

There is a problem in the respiratory tract such as chronic bronchitis.

Ligon pressure.

Be cautious when using this product:

The drug can cause irritation, especially in children.

Drugs that cause drowsiness.

Pain and sedative drugs can increase the effect of drowsiness.

Not used with other drugs containing acetaminophen.

Stop medication and consult your doctor if:

Feeling restlessness, dizziness or insomnia.

Pain, nasal congestion, or more severe cough or lasting more than 5 days.

Fever heavier or lasting more than 3 days.

Skin red or swollen.

There are new symptoms.

Cough recurrent or accompanied by fever, skin rash or prolonged headache.

Medicinal interaction

Do not take this medication if you are taking Monoamine Oxidase inhibitors (IMAO) (some drugs for depression, mental or emotional disease, or Parkinson's disease) or within 2 weeks after stopping the IMAO medications. If you do not know whether the drug is taking as prescribed by a doctor containing imao or not, must consult a doctor or pharmacist before taking this drug.

Anti -seizures (including Phenytoin, Barbiturat, carbamazepin ), Isoniazid can increase the toxicity of acetaminophen on the liver. Simultaneous use of phenylephrin with amines that have a sympathetic nerve effect can increase the unwanted effects of cardiovascular.

Phenylephrine may reduce the effectiveness of beta blockers and anti -hypertension drugs (including debilisoquin, guanethidin, reserpine, methyldopa). Risk of hypertension and unwanted effects on cardiovascular can be increased.

Three -round antidepressants ( amitriptylin , imipramin): may increase the unwanted effects of phenylephrin.

Simultaneous use of phenylephrin with mushroom alkaloid (ergotamine and methyl servers): increases the poisoning of chicken spurs.

Simultaneous use of phenylephrin with digoxin: increases the risk of abnormal heartbeat or heart attack.

Simultaneous use phenylephrine with Atropin will block the slow -working effect of the reflective heart rate caused by phenylephrine.

ethanol or sedative drugs can increase the central nervous system inhibitors of chlorpheniramin.

chlorpheniramine inhibits phenytoin metabolism and can lead to phenytoin poisoning.

Concomitance Dextromethorphan with central neurological inhibitors can enhance the central neurological inhibitor of these drugs.

quinidine inhibits cytochrom P450 2D6, increasing the concentration of dextromethorphan in serum and increasing the unwanted effects of dextromethorphan.

Storage

In a dry place, at temperatures from 15 ° C to 30 ° C. Avoid light.

Expiry date: 36 months from the date of manufacture. Do not take the drug when expiry to use. To be out of reach of children. Read the instructions carefully before use.

Produced at OPV Pharmaceutical Joint Stock Company (27 Road 3A, Bien Hoa II Industrial Park, P.An Binh, Bien Hoa City, Dong Nai).

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