Amgifer 100mg Drogsan treatment in dysmenorrhea, chronic rheumatoid arthritis, back pain (1 blister x 15 tablets)

Dosage form Box of 1 blister x 15 tablets
Specifications Flurbiprofen
Ingredient Drogsan Ilaclari Sanayi Ve Ticaret A.S - Türkiye

Ingredient

Composition information	Content
Flurbiprofen	100mg

Uses

indicated

gynecological:

Denetic pain, after finding the cause.

rheumatism:

Symptomatic treatment for a long time:

Chronic rheumatoid arthritis, especially rheumatoid arthritis; Arthritis or syndrome similar to Fiessinger-Leroy-Riter syndrome and rheumatism due to candles.

Rheumatoid external joints (such as arthritis around the shoulder-hand, tendonitis ...).

Neurological root pain. Flurbiprofen is a Racemic mixture of (+) S and (-) R-anantiomers. Like other nonsteroidal anti -inflammatory drugs, Flurbiproofen has an analgesic, antipyretic, anti -inflammatory effect. The mechanism of action of the drug is Prostaglandin Synthetase inhibitors and thus preventing prostaglandin, thromboxan and other products of cyclooxygenase.

pharmacokinetics

absorption:

The maximum concentration in the serum reaches 1 hour and 30 minutes after drinking.

The semi -cancellation time is from 3:30 to 4 hours. The drug is combined with plasma proteins at 99%. The maximum concentration in the epidemic is about 1/4 of the maximum concentration (cmax) in plasma.

Flurbiproofen has no enzyme induction effect.

only excreted through urine with 20-25% in the form of unchanged, and 75-80% in the form of metabolites in connected to glucuronique acid. Flurbiprofen's pharmacokinetics does not change in the elderly.

Before taking Amgifer 100mg Drogsan treatment in dysmenorrhea, chronic rheumatoid arthritis, back pain (1 blister x 15 tablets)

How to use

exclusively for adults and children over 15 years old.

Swallow the pill with a large glass of water, during meals.

Dosage

Treatment of dysmenorrhea: 1 tablet of 100mg, 2 to 3 times daily at the beginning of the pain, maintain until the symptoms are gone.

Treatment of rheumatism:

Attack dose: 1 tablet of 100mg × 3 times daily. Gastrointestinal bleeding, hypertension, acute renal failure, respiratory failure and coma may occur, but very rare. Anaphylaxis has been reported to oral treatment of nonsteroidal anti -inflammatory drugs, and may occur after taking more than 1 dose.

Handling: usually symptomatic treatment and support. There is no specific antidote. If you have an overdose, you need to apply the following measures to increase elimination and inactivity: gastric lavage, vomiting and diuretic, drinking activated carbon or salt bleach. If severe: hemorrhage or blood transfusion.

What to do when you forget 1 dose? If near the next dose time, skip the forgotten dose, and take the next dose as usual. Do not take 2 doses at the same time.

Side Effects

Common, ADR> 1/100:

digestive: stomach disorders such as nausea, vomiting, stomach pain, indigestion, defecation disorders (diarrhea, constipation).

Systemic body: allergic reaction, urticaria. hemolytic anemia.

Rare, ADR

Skin reaction: Puffiness of Stevens-Johnson syndrome, Lyell syndrome.

Eye: vision disorders Can cause urinary disorders, and may reduce the excretion of calcium through the kidneys.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Hypersensitivity to any ingredient of the drug. Using the drug can cause asthma attacks in some people, especially in people who are allergic to aspirin.

Be cautious when using

because the drug can cause stomach manifestations, sometimes severe, especially in patients being treated with anticoagulant drugs, especially monitoring symptoms on the gastrointestinal tract.

In case of gastrointestinal bleeding, treatment must be stopped.

Be careful when using Flurbiproofen in infection patients or at risk of infection, although well controlled, due to:

Flurbiproofen may reduce the body's resistance. (such as stomach ulcer, diaphragm hernia, gastrointestinal bleeding, ...).

The effect of the drug on the ability to drive and operate machinery

The drug can cause headaches, dizziness (rarely), need to be cautious for people who are driving and operating machinery.

Use drugs for women during pregnancy and lactation

Pregnant women:

In humans, there has not been any influence that causes deformities in the fetus. However, it is necessary to do more epidemiological studies to eliminate this risk.

In the last 3 months of pregnancy, the inhibitors of prostaglandin synthesis may cause:

Fetus: Heart poisoning and renal dysfunction.

Therefore, the use of NSAIDs must be considered in the first 5 months of pregnancy. Except for some very limited cases, the drug is applied in obstetrics with special control, absolutely banned NSAIDs in the last 3 months of pregnancy.

breastfeeding women:

NSAIDs are excreted through breast milk, so be careful to avoid being used for breastfeeding women.

Interaction

Oral anticoagulant: Increased risk of hemorrhage of oral anticoagulant drugs. In the blood to toxicity, due to reducing the lithium excretion through the kidneys. In addition, it reduces the effect of lowering pressure. NSAIDS. Blood.

Storage

Keep the drug at a temperature below 30 ° C.

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