Aminoplasmal intravenous solution 5% B.Braun provides amino acids (250ml)

Dosage form 10 bottles
Specifications Lysine, L-lucin, L-Isoleucine, Arginine, Methionin, L-Glutamic Acid, Glycin, Alanine, L-Threonin, L-Histidine, Proline, L-Tyrosine, L-Valine, L-Tryptophan, L-Phenylalanine, Aspartic Acid, DL-Serine
Ingredient Vitamin deficiency anemia, anemia due to vitamin B12 deficiency, amino acid metabolism disorders, B vitamins, weakness

Ingredient

Composition information	Content
Lysine	1.07
L-leucin	1.1125mg
L-ISOLEUCINE	0.625
Arginine	1.4375
Methionin	0.55
L-Glutamic Acid	0.9
Glycin	1.5
Alanine	1.3125
L-Threonin	0.525
L-histidine	0.375
Proline
L-Tyrosine	0.1
L-Valine	0.775
L-tryptophan	0.2
L-phenylalanine	0.5875
Aspartic acid	0.7
DL-Serine	0.2875

Uses

Indications

5% aminoplasmal drugs are indicated in the following cases:

Provides amino acids as a substrate for protein synthesis in nourishing mode through intravenously, oral and gastrointestinal tract is impossible, missing or contraindicated. Learning

Classification: Nutrition solution through vein.

ATC Code: B05B A10.

The purpose of intravenous nutrient solution is to provide essential nutrients for the development, maintenance and restoration of body tissues.

Amino acids are of special importance because they are an essential part of protein synthesis.

Amino acids are transmitted through intravenously into the vein and join the amino acid fund for free endogenous acid inside the cell. Both endogenous and external amino acids are used as a substrate for the synthesis of function protein and structure of the body.

To avoid the metabolism of amino acids producing energy, and also to provide other energy consumption processes of the body, should be used with energy suppliers (in the form of carbohydrates or fat).

Electrolytes used in intravenous nutrition help maintain the serum needed for the physiological process of the cell that the electrolyte level in the cell is closely adjusted as a prerequisite. In addition, the combination of electrolytes with amino acids is beneficial, due to the internal properties of each substance, it can be combined with each other.

pharmacokinetics

Because aminoplasmal B. Braun 5% E is transmitted through intravenously, the bioavailability of amino acids and electrolytes reaches 100%.

Amino acid components of aminoplasmal B. Braun 5% E are set on the basis of clinical research on the concentration of amino acids in plasma when transmitting amino acids. In Aminoplasmal B. Braun 5% E concentration of each amino acid has been selected so that when transmitting that solution, the relative increase of amino acids in plasma is even as much as possible. This means that the home of the amino acids in plasma is maintained as long as possible when transmitting aminoplasmal B. Braun 5% E. The amino acid part is not involved in the synthesis of protein metabolized as follows:

Amino acid group is separated from the carbon frame by the amino.

Carbon chain or directly oxidized into CO2 or used as a substrate in the process of forming glucose in the liver.

The amino group is also metabolized in the liver into urea.

Before taking Aminoplasmal intravenous solution 5% B.Braun provides amino acids (250ml)

How to use

Methods of transmission and transmission time

intravenously:

Aminoplasmal B. Braun 5% E can be used for a long time as intravenous nutrition.

Aminaplasmal B. Braun 5% E is only a component of intravenous nutrition. In intravenous nutrition, the supply of amino acids must be combined with providing energy sources, essential fatty acids, vitamins and micronutrients.

Dosage

The dose is adjusted according to the needs of each patient about amino acids, electrolytes and body fluids, depending on the patient's clinical condition (nutrition status and/or the level of nitrogen catalogue due to pathology).

Adults and adolescents from 15 - 17 years old

Average daily dose: 20 - 40 ml/kg body weight is equivalent: 1.0 - 2.0 g of amino acid/kg body weight. Equivalent: 1400 - 2800 ml for patients weighing 70 kg.

Maximum daily dose: 40 ml/kg body weight is equivalent: 2.0 g amino acid/kg body weight. Equivalent: 140 g amino acid for patients weighing 70 kg. Equivalent: 2800 ml for patients weighing 70 kg.

Maximum transmission speed and drops: 2.0 ml/kg body weight/hour. Equivalent: 0.1 g of amino acid/kg body weight/h. Equivalent: 45 drops/minute for patients weighing 70 kg. Equivalent: 2.34 ml/minute for 70 kg.

Children and teenagers until the age of 14:

The recommended dose given here is the average value of orientation. The dose must be corresponding to the age of each patient, the stage of development of the disease and the disease.

Daily dose for children from 3-5 years old: 30 ml/kg body weight/day and equivalent to 1.5 g of amino acid/kg body in/day.

Daily dose for children from 6 - 14 years old: 20 ml/kg body weight/day and equivalent to 1.0 g of amino acid/kg body in/day.

Maximum transmission speed: 2.0 ml/kg body weight/hour, corresponding to 0.1 g of amino acid/kg body weight/hour.

In case the amount of amino acid requires 1 g/kg body in/day or more, special attention must be paid to the limit of the fluid. To avoid overloading, the amino acid solution can be used with larger content in this case.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms:

Overdose or transmission can lead to intolerant reactions and may be manifested in the form of nausea, chills, vomiting and amino acid losses through the kidney.

Treatment:

If the reaction is not absorbed, it is necessary to stop transmitting temporarily and then continue to transfer it at a lower speed.

What to do when forgetting a dose?

Side Effects

When using aminoplasmal 5%, you may experience unwanted effects (ADR).

Has unwanted effects, but the side effects are not specific to this product but may appear as the results of venous nurturing, especially at the beginning stage.

Less ( 1/1000)

Gastrointestinal disorders: Nausea, vomiting.

general disorder: headache, chilling, fever.

Note: Please notify the doctor the unwanted effects are not listed in this manual when using the drug.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Aminoplasmal 5% contraindicated drug in the following cases:

sensitive to amino acids present in solution.

Metabolism of abnormal amino acids.

Serious circulatory disorders threaten to life, for example shocking.

Hemolytic reduction.

Metabolic acid infection.

Progressive liver disease.

Severe kidney failure is not dialysis or hemorrhage.

Pathological or high serum concentration of any electrolyte in the product composition.

Children under 2 years old.

General contraindications in intravenous infusion: loss of heart failure, acute pulmonary edema, water stasis.

Precautions when using

aminoplasmal B. Braun 5% E is used carefully and only after careful reminders between expected benefits and potential risks in patients with amino acid metabolic disorders due to other causes than being mentioned in the "Contrain".

In patients with liver failure, renal failure must be adjusted for each patient.

Need to carefully check patients with serum osmotic pressure.

In case of dehydration should be adjusted by providing sufficient fluid and electrolytes before using nutrient solution through static sugar.

During the treatment process, there must be regular monitoring of serum, blood sugar, liquid balance, acid-base balance, kidney function (bun, creatinine).

It is also advisable to control serum protein and test liver function.

Should be careful when transmitting a large amount of fluid to patients with heart failure.

Aminaplasmal B. Braun 5% E can be used as part of nourishing throughout the venous line when combining the appropriate amount of energy supplements such as (carbohydrate solution, fat emulsion), vitamins, trace elements.

If aminoplasmal B. Braun 5% E is used in combination with other nutrient solutions, peripheral intravenous infusion depends on the osmotic pressure of the mixed solution.

Should check daily in the position of transmitting signs of inflammation or infection.

Special warnings when processing and shipping

Do not use if the solution is not transparent or if the bottle or bottle cap shows signs of damage.

Must use aseptic transmission line.

Each bottle is only used once. The non -used part must be canceled and not to use for the next time.

If necessary to add other nutrients such as carbohydrates, lipids, vitamins and trace elements to this drug to provide nutritious venous nutrition, the mixing process must be done under strict sterile conditions. The mixing should be completely mixed and must check the compatibility of the added substances.

The ability to drive and operate machinery

No.

Pregnancy

has not conducted research in pregnant women. There is no preclinical data related to the use of aminoplasmal B. Braun 5% E during pregnancy.

Should only use aminoplasmal B. Braun 5% E for pregnant women after careful evaluation of benefits and risks possible.

Breastfeeding period

has not conducted research in nursing women. Aminoplasmal B. Braun should only be used for 5% e for breastfeeding women after careful assessment of their benefits and risks.

Drug interaction

unknown.

Storage

Keep pills out of reach and vision of children.

Keep the bottle in carton to avoid light. Do not leave the drug in a temperature of over 30 ° C.

No cold storage.

Storage under 15 ° C can lead to crystalline crystallization, but it is easy to dissolve when heating up to 30 ° C until the solution is completely dissolved. Shake the bottle gently to homogeneous mixture when heating.

Expiry date:

Expiry date after opening: 24 months from the date of manufacture.

The limit after mixing with other ingredients: from the viewpoint of germs, the solution after mixing must be used immediately. If not used immediately, the time and condition of preserving the solution after mixing belongs to the responsibility of the user and often must not exceed 24 hours at 2 - 8 ° C.

Do not use overdue drugs indicated on the packaging.

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