Aminoplasmal intravenous solution 5% B.Braun provides amino acids (500ml)

Dosage form 10 bottles x 500ml
Specifications Isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, arginine, histidine, alanine, glycine, aspartic acid, glutamic acid, proline, serine, tyrosine, sodium acetate trihydrate, sodium chloride, sodium hy di
Ingredient Malnutrition

Ingredient

Thành phần cho 250ml

Composition information	Content
Isoleucine	0.625g
Leucine	1.1125g
Lysine	0.8575g
Methionine	0.55g
Phenylalanine	0.5875g
Threonine	0.525g
Tryptophan	0.2g
Valine	0.775g
Arginine	1.4375g
Histidine	0.375g
Alanine	1.3125g
Glycine	1.5g
Aspartic Acid	0.7g
Glutamic acid	0.9g
Proline	0.6875g
Serine	0.2875g
Tyrosine	0.1g
Sodium acetate trihydrate	0.34025g
Sodium chloride	0.241g
Sodium hydroxide	0.035g
Potassium Acetate	0.61325g
Magnesium chloride hexahydrate	0.127g

Uses

indications

Aminoplasmal B.Braun 5% E is indicated in the following cases:

Provides amino acids as a substrate for protein synthesis in nourishing mode through intravenous tract, orally and gastrointestinal tract is impossible, missing or contraindicated.

In intravenous nurturing, always transmitting amino acid solution in combination with an appropriate amount of solution to provide energy, for example, carbohydrate solutions.

The purpose of intravenous nutrient solution is to provide essential nutrients for the development, maintenance and restoration of the body's tissues. Amino acids are of special importance because they are an essential part of protein synthesis.

Amino acids are transmitted through intravenously into the vein and join the amino acid fund for free endogenous acid inside the cell. Both endogenous and external amino acids are used as a substrate for the synthesis of function protein and structure of the body.

To avoid amino acid metabolism produces energy, and also to provide other energy consumption processes of the body, should be used with energy suppliers (in the form of carbohydrates or fat). The electrolyte used in intravenous nutrition helps maintain the necessary serum level for the physiological process of the cell that the electrolyte level in the cell is closely adjusted as a prerequisite. In addition, the combination of electrolytes with amino acids is beneficial, due to the interiority of each substance.
pharmacokinetics

Because aminoplasmal B. Braun 5% E is transmitted through intravenously, the bioavailability of amino acids and electrolytes reaches 100%. Amino acid components of aminoplasmal B. Braun 5% E are established on the basis of clinical research results on the concentration of amino acids in plasma when transmitting amino acids. In aminoplasmal B. Braun 5% E of each amino acid concentration has been selected so that when the solution is transmitted, the relative increase of amino acids in plasma is even as well as possible. This means that the navilage of amino acids in plasma is maintained as long as possible when transmitting aminoplasmal B. Braun 5% E.

The amino acid part is not involved in the synthesis of protein metabolized as follows. The amino acid group is separated from the carbon frame by amino metabolism. Carbon or oxidized chain directly into CO2 or used as a substrate during the formation of glucose in the liver. The amino group is also metabolized in the liver into urea.

Before taking Aminoplasmal intravenous solution 5% B.Braun provides amino acids (500ml)

How to use

Use intravenous lines.

Transmission and transmission time:

Aminoplasmal B. Braun 5% E can be used every time the nutrition through the intravenous sugar is specified.

Aminoplasmal B. Braun 5% E is only a component of intravenous nutrition. In intravenous nutrition, supplying amino acids must be combined with providing energy sources, essential fatty acids, vitamins and trace elements. Ly).

Adults and adolescents aged 15-17 years old

Average daily dose: 20 - 40 ml/kg body weight.

equivalent: 1.0 - 2.0 g amino acid/kg body weight.

equivalent: 1400 - 2800 ml for patients weighing 70 kg.

Maximum daily dose: 40 ml/kg body weight.

Equivalent: 2.0 g amino acid/kg body weight.

equivalent: 140 g amino acid for patients weighing 70 kg.

equivalent: 2800 ml for patients weighing 70 kg.

Maximum transmission speed and drops: 2.0 ml/kg body weight/hour.

Equivalent: 0.1 g of amino acid/kg body weight/hour.

Equivalent: 45 drops/minute for patients weighing 70 kg equivalent: 2.34 ml/min for patients weighing 70 kg.

Children and teenagers up to 14 years old

The recommended dose given here is the average value of orientation. The dose must be corresponding to the age of each patient, the stage of development of the disease and the disease.

Daily dose for children from 3-5 years old: 30 ml/kg body weight/day and equivalent to 1.5 g of amino acid/kg body weight/day.

Daily dose for children from 6 - 14 years old: 20 ml/kg body weight/day and equivalent to 1.0 g of amino acid/kg body weight/day.

Maximum transmission speed:

2.0 ml/kg body weight/hour, corresponding to 0.1 g of amino acid/kg body weight/hour.

In case the amount of amino acid requires 1 g/kg body weight/day or more, must pay attention to pay attention to the limit of the fluid put into the body. To avoid overloading, the amino acid solution can be used with larger content in this case.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

Overdose or transmission can lead to intolerant reactions and may be manifested in the form of nausea, chills, vomiting and amino acid losses through the kidney.

Treatment

If the reaction is not absorbed, it is necessary to stop transmitting temporarily and then continue to transfer it at a lower speed.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose?

Side Effects

When using aminoplasmal B.Braun 5% E, you may experience unwanted effects (ADR).

Has unwanted effects, but the side effects are not specific to this product but may appear as the results of venous nurturing, especially at the beginning stage.

Uncommon (ADR 1/1000)

Gastrointestinal disorders: Nausea, vomiting.

Common disorders: headache, chilling, fever.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Aminoplasmal B.Braun 5% E Contrainodic in the following cases:

sensitive to amino acids present in solution.

Metabolism of abnormal amino acids.

Serious circulatory disorders that are life -threatening, for example shocking.

Hemolytic reduction.

Metabolic acid infection.

Progressive liver disease.

Severe kidney failure is not dialysis or hemorrhage.

Pathological or high serum concentration of any electrolyte in the product composition.

Children under 2 years old.

Commonly contraindicated in intravenous infusion:

Uncount heart failure.

Acute pulmonary edema.

Conditions of water.

Be cautious when used

Aminoplasmal B. Braun 5% E is used carefully and only after careful consideration between expected benefits and risks in patients with amino acid metabolic disorders due to causes other than the reasons mentioned in the "Contraindications" section.

In patients with liver failure, renal failure must be adjusted for each patient.

Need to carefully check patients with hyperproof pressure.

In case of dehydration, adjustment should be adjusted by providing enough fluid and electrolytes before using intravenous nutrient solution.

During the treatment process, there must be regular monitoring of serum, blood sugar, liquid balance, acid -base balance, kidney function (bun, creatinine).

should also control serum protein and check liver function.

Should be careful when transmitting a large amount of fluid to patients with heart failure.

Aminoplasmal B. Braun 5% E can be used as a part of nurturing throughout the venous line when combining the appropriate amount of energy supplements such as (carbohydrate solution, fat emulsion), vitamins, trace elements.

If aminoplasmal B. Braun 5% E is used in combination with other nutrient solutions, peripheral intravenous infusion depends on the osmotic pressure of the mixed solution.

Should check daily in the position of transmitting signs of inflammation or infection.

The ability to drive and operate machinery

no.

Pregnancy

has not conducted research in pregnant and lactating women. There is no sieve data related to the use of aminoplasmal B. Braun 5% E during pregnancy.

Should only use aminoplasmal B. Braun 5% E for pregnant and lactating women after careful evaluation of benefits and risks as possible.

The period of breastfeeding

has not conducted research in pregnant and lactating women. There is no sieve data related to the use of aminoplasmal B. Braun 5% E during pregnancy.

Should only use aminoplasmal B. Braun 5% E for pregnant and lactating women after careful evaluation of benefits and risks as possible.

Interactivity

Not known.

Storage

Keep the bottle in carton to avoid light.

Do not leave the medicine at a temperature of over 30 ° C.

No cold storage.

Storage less than 15 ° C can lead to crystalline crystallization, but it is easy to dissolve when heating up to 30 ° C temperature until the solution is completely dissolved. Shake the bottle gently to homogeneous mixture when heating.

Special warnings when processing and shipping

Do not use if the solution is not transparent or if the bottle or bottle cap shows signs of damage.

Must use aseptic transmission line.

Each bottle is only used once. The non -used part must be canceled and not to use for the next time.

If necessary to add other nutrients such as carbohydrates, lipids, vitamins and trace elements to this drug to provide nutritious venous nutrition, the mixing process must be done under strict sterile conditions. The mixing should be completely mixed and must check the compatibility of the added substances.

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