Amloboston 5 Boston medicine treats high blood pressure, angina (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Amlodipine
Ingredient Boston Vietnam Pharmaceutical Joint Stock Company

Ingredient

Composition information	Content
Amlodipine	5mg

Uses

Indications

Treatment of hypertension support patients with metabolic complications such as diabetes, preventive treatment in stable angina.

Pharmacokological

amlodipin is a derivative of dihydropyridine that chooses a calcium line through plain muscle cell membranes, directly acting on blood vessels in the heart and muscle.

Amlodipine has anti -hypertension effects by directly leading to inert muscles around peripheral arteries, reducing kidney blood vessel resistance, thus increasing the flow and improving kidney function.

Amlodipin has no adverse effects on plasma lipid concentrations or glucose metabolism, so it can be used amlodipine to treat high blood pressure in people with diabetes. The drug has a slow effect, so there is a risk of acute hypotension or a reflex tachycardia and the drug has a good effect on standing - lying - sitting and even working.

Amlodipine stretches peripheral arteries, reduces peripheral resistance, reduces the heart attack, reduces the need for oxygen and energy to the heart, thus reducing the risk of angina. The drug also causes coffee coronary artery in anemia area and an increased blood supply area to provide oxygen for patients with spasmic angina (Prinzmetal syndrome), thus reducing nitroglycerin demand and the risk of nitroglycerin resistance may decrease. The time for anti -angina effect is 24 hours. People with angina can use amlodipine combined with beta blockers and always use with nitrate (basic treatment of angina).

pharmacokinetics

Biological comfort of amlodipin when drinking about 60 - 80% and not affected by food. The peak concentration reaches 6 - 12 hours after drinking. Stable plasma concentrations reach 7 to 8 days after taking the drug once a day.

The distribution of approximately 21L/kg body weight, the drug is linked to the blood protein of more than 98%, the semi -discharged time in plasma is from 30-40 hours.

Metabolic mainly through the liver, the inactive metabolites are excreted mainly through the urine. In people with liver failure, Amlodipine's exhaust time is increased, so it may have to reduce the dose or extend the time between the dose.

Before taking Amloboston 5 Boston medicine treats high blood pressure, angina (5 blisters x 10 tablets)

How to use

Take oral use.

Dosage

must use the appropriate dose for each patient under the instructions of the treating doctor.

Normal dose: 5mg x 1 time daily.

Can increase the dose to: 10mg x 1 time daily

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

When amlodipine overdose occurs, cardiovascular monitoring, symptomatic treatment with gastric lavage. If necessary, electrolytes must be adjusted. For patients with reduced circulatory volume, sodium chloride infusion is 0.9%. In case of severe hypotension, intravenously intravenous solution of sodium chloride and adrenalin must be intravenous. Differences are not effective.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Amloboston 5mg, you may experience unwanted effects (ADR).

The most common side effect of Amlodipin is to cover the ankle from light to medium, related to the dose. This effect is about 3% when used by 5mg/day and 11% when using 10mg/day.

Common

Ankle edema, headache, dizziness, hot feeling, fatigue, weakness, chest drum, cramps, shortness of breath, nausea, unbelievable ...

rarely

Excessive hypotension, fast heart, chest pain, itchy rash, muscle pain, joint pain, sleep disorders.

rarely

Systemic Systema, hyperplasia, urticaria, hyper enzyme, hyperlem of blood glucose, confusion, Hong Ban ...

Notify the doctor with unwanted effects when using the drug.

Warnings

Contraindicated

Not used for people who have not been treated stable, too hypersensitivity to any component of the drug, cautious when using, impaired liver function, aortic stenosis, cardiomyopathy.

The ability to drive and operate machinery

does not impact on the operator of the train machinery.

Pregnancy and breastfeeding

There has been no notice of evaluation of Amlodipin's accumulation in breast milk.

Drug interaction

Anesthesia may increase the hypotension effect of amlodipine.

When using lithium with amlodipine can cause nerves, nausea, diarrhea.

Anti -inflammatory drugs, especially indomethacin, can reduce the anti -hypertension effect of amlodipine.

High -linked drugs with protein (such as Coumarin, Hytantoin ...) must be used with amlodipine because amlodipine is also highly linked to protein, so the free concentration of the above drugs can change in serum.

Storage

Where dry, less than 30 ° C, avoid light.

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