Amoxicillin 250mg Imexpharm oral oral

Dosage form 12 package box
Specifications Amoxicillin
Ingredient Imexpharm Pharmaceutical Joint Stock Company

Ingredient

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Composition information	Content
Amoxicillin	250mg

Uses

indications

Amoxicillin drugs are indicated in the following cases:

Treatment of bacterial infections caused by drugs sensitive to drugs at the positions: upper respiratory tract, lower respiratory tract, bile bacteria, gastrointestinal tract, urinary tract - genital, endocarditis prevention. The drug works by inhibiting mucopeptide biosynthesis into bacterial cells. The effect of the drug includes both gram -negative and gram -positive bacteria such as streptococcus, staphylococcus aureus without penicillinase, H.influenzae, diplococcus pneumoniae, N.Gonorrheae, E.coli, Proteus Mirabilis.

Dynamic pharmacokinetics

amoxicillin sustainable in gastric acid environment. Absorption is not affected by food, fast and completely through the gastrointestinal tract compared to ampicillin. When taken at the same dose like ampicillin, the concentration of amoxicillin peak in plasma is at least 2 times higher. Amoxicillin is quickly distributed into most tissues and fluids in the body eliminating brain tissue and cerebrospinal fluid, but when the meninges are inflamed, Amoxicillin diffuses easily. After taking the dose of 250 mg amoxicillin 1 - 2h amoxicillin concentration in the blood reaches about 4-5 mcg/ml. When taking the dose of 500mg, Amoxicillin concentration reaches about 8 - 10 mcg/ml. Double dose can increase the concentration of medication in the blood. Amoxicillin oral or injected evenly for the same concentrations of drugs in plasma. Amoxicillin's half -life is about 61.3 minutes; longer in infants and the elderly. In people with kidney failure, the half -life of the drug is about 7-20 hours. About 60% of the oral dosage of Amoxicillin eliminates raw form into the urine within 6 - 8 hours.

Probenecid extends the waste time of amoxicillin through the kidney.

Amoxicillin has high concentrations in bile fluid and a part of the feces.

Before taking Amoxicillin 250mg Imexpharm oral oral

How to use

drugs in the form of mixed nuggets, oral use.

Dosage

Common dose: 250 mg - 500 mg, every 8 hours.

Children to 10 years: 125 mg - 250 mg, every 8 hours.

Children under 20 kg: 20 - 40 mg/kg body weight/24 hours, divided 3 times (every 8 hours).

Children under 3 months of age: Maximum dose of 30 mg/kg body weight/24 hours, divided 2 times (every 12 hours).

Higher dose, single dose or in short phases, used in some diseases:

abscess around the teeth: 3 g, repeat again after 8 hours.

Cl Creatinin do when using overdose? The imbalance of water - electrolytes should be treated as symptoms. In the process of using high doses of amoxicillin, it is necessary to maintain a satisfactory amount of drinking water and excreted out of the urinary tract to minimize the possibility of amoxicillin crystal crystal.

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using the drug, there are common unwanted effects (ADR) such as:

Common: Outdoor (3 - 10%), usually appears slowly, after 7 days of treatment. agitation, struggle, anxiety, insomnia, confusion, change of behavior and/or dizziness; Anemia, thrombocytopenia, thrombocytopenia, Eosin hypernagus, leukopenia, granulocytosis.

Notify the physician with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Amoxicillin drug is contraindicated in the following cases:

Hypersensitivity to penicillin or cephalosporin groups.

Be cautious when using

Please see more information about the drug in the instruction sheet of the use of the drug attached.

Need to be very cautious when taking drugs for patients in the following cases:

must periodically check the liver and kidney function during the long -term treatment. Quincke, Anaphylaxis, Stevens - Johnson syndrome, must stop amoxicillin therapy and immediately treat emergency treatment with adrenalin, oxygen, intravenous corticoid therapy and ventilation, including intra -intubation and never treatment with penicillin or cephalosporin again.

The effect of the drug on driving and operating machinery

The drug does not affect the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

Pregnant women: Safety when using amoxicillin during pregnancy has not been clearly defined. Therefore, only use the drug when really necessary. However, there is no evidence of harmful effects for the fetus when using amoxicillin for pregnant women.

Lactating women: Because amoxicillin is excreted in breast milk, it is necessary to be cautious when taking the drug during breastfeeding.

Drug interaction

Absorb AMOXICillin is not affected by food in the stomach, so it can be taken before or after meals. There is an antagonist between amoxicillin and sthere bacteria, sthen with Nhu Chloramphenicol, tetracyclin.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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Disclaimer

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