Amoxicillin Capsules BP 500mg Brawn treats infection (10 blisters x 10 tablets)

There is a history of anaphylaxis or serious hypersensitivity reaction to any type of beta lactam.

Be cautious when using

Hypersensitivity reaction

Before starting treatment with amoxicillin, careful consideration of a history of hypersensitivity reactions to penicillin, cephalosporin or other beta -lactam inhibitors. There has been a serious hypersensitivity report and sometimes fatal (including skin anaphylactic reactions and serious side effects on the skin) in patients using penicillin. These reactions are more likely to occur in people with hypersensitivity and allergies. If allergic reactions occur, amoxicillin should be stopped and appropriate alternative therapy.

Unpake microorganisms

Amoxicillin is not suitable for treating some types of infections unless the pathogenic bacteria have been recognized and known as sensitive or highly likely to be appropriate bacteria to treat amoxicillin. This is especially applied when considering the treatment of patients with urinary tract infections and severe infections in the ear, nose and throat.

convulsions

Convulsions can occur in patients with impaired renal function or in patients with high doses or in patients with risk factors (such as history or epilepsy or meningitis).

kidney failure

In patients with renal failure, the rate of amoxicillin secretion will decrease depending on the degree of decline and may need to reduce the total daily dosage of amoxicillin.

Skin reaction

The occurrence of the onset of the treatment of the erythema of the whole body fever related to pustules may be a symptom of the provincial -level pustules syndrome (AGEP). This reaction requires stopping amoxicillin and contraindicating any later treatment. Amoxicillin should be avoided if there is suspected monicardulus of infections and appears the phenomenon of erythema is related to this condition after using amoxicillin.

Jarisch reaction - Herxheimer

Jarisch - Herzheimer reaction was reported after taking amoxicillin to treat Lyme disease, which is the direct result of amoxicillin's antibacterial effects on bacteria that cause Lyme, Barrelia Burgerferi. Patients need to be guaranteed that this is a common and self -limited consequence when using antibiotics to treat Lyme disease.

Excessive growth of non -sensitive microorganisms

Leading drugs also occasionally leads to excessive growth of non -sensitive bacteria. Colitis associated with antibiotics has been reported in most antibiotics and the severity of mild to life -threatening. Therefore, it is important to consider this diagnosis in patients with diarrhea, or diarrhea after taking any antibiotic. If the colitis occurs in antibiotics, it is necessary to stop using amoxicillin immediately, and use an appropriate alternative therapy as directed by the doctor, the anti -peristaltic drug is contraindicated in this case.

Treatment for a long time

Periodically assess the function of organs in the body such as kidney, liver and hematological functions are recommended during long -term drug treatment. It is also necessary to report on the liver enzyme index and change the blood count.

anticoagulants

Prothrombin has been reported to rarely occur for patients using amoxicillin, appropriate monitoring when patients use simultaneous anticoagulant and amoxicillin drugs. It may be necessary to adjust the anticoagulant dose to ensure the desired concentration of this drug.

The ureter

In patients with reduced urine, urinary crystals have been observed rarely, mainly in patients using infusion. During the treatment of high doses of amoxicillin, pay attention to supply enough water and control the appropriate amount of urine to reduce the risk of amoxicillin urinary crystals. For patients using bladder catheter, regular checkpoints need catheter.

Interventions in diagnostic tests

Amoxicillin levels in serum and urine can affect certain tests. The high concentration of amoxicillin in the urine leads to the wrong positive results in some chemical tests is very common. It is recommended to use glucose enzyme oxidation when checking the presence of glucose in the urine when the patient is treating amoxicillin. The presence of amoxicillin may falsify the oestriol test results in pregnant women.

The ability to drive and operate machinery

Because the drug can cause some unwanted effects that affect the central nervous system such as dizziness, convulsions, hyperactivity, patients use the drug should be cautious when driving and operating machinery.

Pregnancy

Animal studies have not indicated the harmful effects of drugs on reproductive toxicity, both indirect and direct. The data on the use of amoxicillin during pregnancy in humans is limited, cannot indicate the risk of increased birth defects in children. Amoxicillin can be used in pregnant women if indicated and beneficial to mothers superior to the risk of children.

The breastfeeding period

Amoxicillin is secreted into breast milk in small amounts and is likely to cause sensitivity. Therefore, infant breastfeeding may have diarrhea, mucus infection. In this case, breastfeeding should be stopped. Amoxicillin should only be used for mothers who are breastfeeding after the doctor valuation between benefits and risks.

Drug interaction

Probenecid

Concomitant use with Probenecid is not recommended. Probenecid reduces amoxicillin secretion through the renal tubules, increasing and prolonging the blood amoxicillin levels in the blood.

Allopurinol

Concentrated with Allopurinol may increase the risk of skin allergies.

tetracyclin

Tetracycline and other bactericidal drugs may affect the antibacterial effect of amoxicillin.

Antaginalism is taken orally

Oral anticoagulants and penicillin antibiotics have been widely used in practice without reporting on interaction. However, cases have been recorded in Inr patients maintained by acenocoumarol or warfarin and are indicated for one batch, if necessary to use simultaneously, carefully monitor prothrombin or INR time by adding or stopping amoxicillin. Moreover, it may also be necessary to adjust the anticoagulant dose.

methotrexate

Penicillin may reduce methotrexate excretion, leading to an increased risk of toxicity.