Amoxycilin 250mg Vidipha Treatment of infection (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Amoxicillin
Ingredient Tonsillitis, rhinitis, otitis media, urinary tract infections, acute bronchitis, chronic bronchitis, H.pylori infection (HP), pneumonia

Ingredient

Composition information	Content
Amoxicillin	250mg

Uses

Indications

Amoxicillin 250mg VDP drugs are indicated in the following cases:

Treatment of upper respiratory tract infections. The muscles due to streptococcus, staphylococcus aureus, E. coli sensitive to amoxicillin. Similar to other penicillin, amoxicillin has bactericidal effect, due to inhibition of mucopeptide biosynthesis of bacterial cell walls. In vitro, Amoxicillin are active with the majority of Gram -negative and gram -positive bacteria such as: streptococcal, staphylococcus aureus does not produce penicillinase, h. Influenzae, diplococcus pneumoniae, n. Gonorrheae, e. Coli and Proteus Mirabilis. Like ampicillin, amoxicillin is not active with penicillinase secretion bacteria, especially methicillin staphylococcus aureus, all pseudomonas strains and most of the Klebsiella and Entobacter strains.

Amoxicillin has a stronger printing effect than ampicillin for Enterococcus Faecalis and Salmonella spp., but less effective for Shigella spp. The spectrum of Amoxicillin may be wider when used simultaneously with sulbactam and clavulanic acid, a beta - lactamase inhibitor. There have been reports E. coli resistant to amoxicillin in combination with clavulanic acid (16.8%).

According to the announcement No. 2 and No. 3 of the National Monitoring Program on the drug resistance situation of common pathogenic bacteria (ASTS), E.coli's ampicillin resistance level is 66.7%, Salmonella Typhi is 50%, Shigella is 57.7%, acinetobacter spp. 70.7%, other intestinal bacteria (Citrobacter, Entobacter, Klebsiella, Morganella, Proteus, Serratia, ...) are 84.1%, Streptococcus spp. is 15.4%, of the Enterococcus spp strains. is 13.1% and other Gram -negative bacilli strains (Achromobacter, Charymonas, Flavobacterium, Pasteurella, ...) are 66.7%.

pharmacokinetics

amoxicillin sustainable in gastric acid environment. Absorption is not affected by food, faster and more completely through the digestive tract than ampicillin. When taken at the same dose like ampicillin, the concentration of amoxicillin peak in plasma is at least 2 times higher. Amoxicillin is quickly distributed into most tissues and fluids in the body, except for brain tissue and cerebrospinal fluid, but when the meninges are inflamed, Amoxicillin is diffused easily.

After taking the dose of 250mg amoxicillin 1 - 2 hours, the concentration of amoxicillin in the blood reaches about 4 - 5mcg/ml, when taking 500mg, amoxicillin concentration reaches about 8 - 10mcg/ml. Double dose can increase the concentration of medication in the blood. Amoxicillin oral or injected evenly for the same concentrations of drugs in plasma. Amoxicillin's half -life is about 61.3 minutes, longer in infants and the elderly. In people with kidney failure, the half -life of the drug is about 7– 20 hours long.

About 60% of the oral dosage of amoxicillin waste raw form into the urine within 6 - 8 hours. Probenecid extends the waste time of amoxicillin through the kidney. Amoxicillin has high concentrations in bile fluid and an excretion through feces.

Before taking Amoxycilin 250mg Vidipha Treatment of infection (10 blisters x 10 tablets)

How to use

Oral drugs, can be taken before or after meals.

Dosage

Common dose

Use 250 - 500mg, every 8 hours.

Children to 10 years

Can be used for 125 - 250mg, every 8 hours.

If needed, children 3 - 10 years old otitis media can be used 750mg/time x 2 times/day for 2 days.

Children under 20kg

Can be used for 20 - 40mg/kg/day.

higher doses, single dose or in short phases, used in some diseases.

Treatment of teeth - cars around the teeth or treatment of urinary tract infections

3G dose, repeat again after 8 hours to treat abscesses around the teeth or repeat after 10 - 12 hours to treat uncomplicated urinary tract infections.

To prevent pericarditis in people susceptible to

Use a single dose 3g, 1 hour before the procedure such as tooth extraction.

For patients with severe or recurrent respiratory infections

Use high -dose regimen 3g Amoxicillin x 2 times/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Amoxicillin 250mg VDP, you may experience unwanted effects (ADR).

Digestive: stomach pain, vomiting, diarrhea.

Skin and subcutaneous tissue: Heavy skin rash, urticaria.

Body: Excessive fatigue, lack of energy.

other ADR: convulsions, jaundice or eyes, abnormal bleeding or bruising, pale skin.

Instructions on how to handle ADR

Notify your doctor if you have any abnormal problems when taking the medication.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Amoxicillin 250mg VDP drugs are contraindicated in the following cases:

Patients with a history of allergies to any type of penicillin.

Be cautious when using

Before taking amoxicillin, let doctors and pharmacists know if you are allergic to amoxicillin, penicillin, cephalosporin or any other medication and the drugs you are taking.

Tell your doctor if you have or have kidney disease, allergies, asthma, fever, urticaria or phenylketonuria.

Must periodically check the liver and kidney function during long -term treatment.

If allergic reactions occur such as erythema, rash, anaphylactic shock, Stevens –johnson syndrome, amoxicillin must be stopped and immediately treated emergency treatment with adrenaline, oxygen breathing, intravenous corticoid therapy and ventilation, including internal trachea and never being treated with penicillin or nephalosporin.

The ability to drive and operate machinery

No information.

Pregnancy

There is no evidence of harmful effects for the fetus when using amoxicillin for pregnant women. However, only use the drug when really necessary.

Breastfeeding period

amoxicillin excreted into breast milk, must be cautious when taking the drug during breastfeeding.

Medicinal interaction

nifedipine increases amoxicillin absorption.

When using allopurinol along with amoxicillin or ampicillin will increase the side effects of ampicillin, amoxicillin.

There may be antagonists between amoxicillin killer and bactericidal substances such as chloramphenicol, tetracycline.

Storage

Keep the medicine in a closed box, out of the reach of children.

Store drugs at room temperature, dry place, avoid heat and direct light.

Other drugs

Disclaimer

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