Amursolic Meyer supports to dissolve cholesterol stones (5 blisters x 10 tablets)

Dosage form Box of 5 blisters x 10 tablets
Specifications Ursodeoxycholic acid
Ingredient Cirrhosis, cholecystitis, chronic hepatitis, gallstones

Ingredient

Composition information	Content
Ursodeoxycholic acid	150mg

Uses

indications

Amursolic drugs are indicated in the following cases:

Treatment to dissolve cholesterol stones in people with gallstones with gallbladder still active.

Chronic liver disease treatment, especially cirrhosis due to bile duct obstruction, bile fibrosis.

Pharmacological

Ursodeoxycholic acid is a natural bile acid present in small quantities in human bile. Ursodeoxycholic acid inhibits the synthesis and secretion of cholesterol in the liver and inhibits the absorption of cholesterol in the intestine. The drug is used to dissolve cholesterol -rich stones in patients with gallbladder still active.

Pharmacokinetics

absorption

Ursodeoxycholic acid is highly absorbed through the digestive tract, with a maximum concentration after drinking about 60 minutes and reaching the peak concentration for 3 hours.

Distribution

Ursodeoxycholic acid quickly combined with glycin and taurin in the liver.

Metabolism

The change of intestinal microorganisms and the metabolites of the drug occur when the drug leaves the intestinal liver cycle and is related to the high concentration of lithocholic acid and 7-Ketolochocholic acid during the process of tri tri with ursodeoxycholic acid.

Elimination

The drug is eliminated through the kidneys, breast milk, bile and mainly through stool.

Before taking Amursolic Meyer supports to dissolve cholesterol stones (5 blisters x 10 tablets)

How to use

take a single dosage at dinner before going to bed, or divided into 2-3 times, can divide larger doses before going to bed to combat increased bile cholesterol levels at night.

Dosage

The usual dose: 6 -12 mg/kg/day.

Obesity patients: Dosage can increase to 15 mg/kg/day.

The treatment lasts from 6 to 24 months depending on the size and composition of the stone.

Cirrhosis due to bile duct obstruction: 10-15mg/kg/day divided into 2-4 times.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Symptoms

may have diarrhea. In general, other symptoms of overdose are almost none, because the absorption of ursodexolic acid decreases when the dose increases and thus are more excreted in the feces.

Handling

Treatment of diarrhea symptoms combined with liver restoration with water and electrolytes. Ion exchange resin may be helpful to connect bile acids in the intestine. Encourage liver function test.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Amursolic medicine, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: gallbladder inflammation, flatulence, digestive disorders, paste, peptic ulcer.

nerve: headache, dizziness.

Mental: Insomnia.

Cardiovascular: chest pain.

Respiratory respiratory infections, sinusitis, bronchitis, cough, sore throat, rhinitis.

immune: viral infection, influenza symptoms. liver and kidney: increased creatinine, lost cirrhosis.

musculoskeletal: back pain, joint pain, arthritis, musculoskeletal, muscle pain.

Dermatology: hair loss, rash/rash on the skin.

Hematology: leukopenia, platelet reduction.

Genitals: Dysmenorrhea, Urinary tract infection.

Uncommon, 1/1000

Without information.

Rare, 1/10000

Dermatology: urticaria.

Kidney liver: Increased bile stasis.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Amursolic drug is contraindicated in the following cases

Hypersensitivity to any ingredients of the drug.

Liver dysfunction or bile path abnormalities.

X -barrel stones (calcium stones).

Gallstones have complications or have surgical indications.

Inflammation or stomach ulcers - duodenum.

Children under 12 years old.

Caution when using

In the first 3 months of treatment, liver function parameters such as AST, ALT and Y-AG should be monitored every 4 weeks, then every 3 months.

In the case of treatment of cholesterol gallbladder stones, it is recommended to check the effectiveness of visual diagnosis after 6 months. If X-rays do not see gallbladder, calcified gallstones, gallbladder reduction or frequent pain of bile cramps, amursolic is not used.

If diarrhea, dose reduction, in case of diarrhea remains, should stop the drug.

Avoid coordinating with liver toxic drugs.

The ability to drive and operate machinery

does not affect.

Pregnancy

There is no adequate data on the use of ursodeoxycholic acid, especially in the first three months of pregnancy. Animal studies have shown the likelihood of monitoring in the early stages of pregnancy. Therefore, the drug is not used during pregnancy unless it is really necessary.

The period of breastfeeding

There is no clinical data because of the safety of ursodeoxycholic acid in breastfeeding women. Therefore, Amursolic is not recommended for this group of patients.

Interactive drug

Avoid coordinating with drugs that increase cholesterol stones such as estrogen, blood lipid anti -lipid drugs such as clofibrat.

Avoid using antacids, activated carbon and cholestyramin, due to reducing the activity of the drug.

Storage

In a dry place, the temperature does not exceed 30 ° C, avoiding direct light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.