An Thien nuggets of An Thien treatment of stomach - duodenal ulcer (30 packs)

Dosage form 30 package box
Specifications Sucralfat

Ingredient

Thành phần cho 1 gói

Composition information	Content
Sucralfat	1g

Uses

Indications

Somastop An Thien is indicated in the following cases:

Adults and children over 15 years old

Short -term treatment (up to 8 weeks) duodenal ulcer, benign stomach ulcers, chronic gastritis.

Preventive ulcerative prophylaxis in children is being treated for a strong treatment, treatment of benign ulcer - benign stomach.

Pharmacokic

Sucralfat is aluminum salt of sulfate disaccarid, used for short -term gastrointestinal ulcer. The drug has a local effect (ulcer) than the body effect.

The mechanism of action of the drug is to create a complex with substances such as albumin and fibrinogen of the adhesive leaking fluid with ulcers to form a barrier that prevents the effect of acid, pepsin and bile. Sucralfat is also bound on the stomach and duodenum mucosa with a much lower concentration than the ulcerative position. Sucralfat also inhibits the activity of pepsin, attached to bile salts to increase Prostaglandin E2 production and stomach mucus.

pharmacokinetic

absorption

Sucralfat absorbs very little (

Distribution

Sucralfate on the spot to ulcerative, non -linked gastrointestinal positions with Al and Sucrose Octasulfate.

Metabolism

Sucralfate reacts with hydrochloride acid in the stomach into non -metabolic sucrose sulfate.

Elimination

90% of sucralfate is excreted in the feces, a very small amount is absorbed and excreted into the urine in the form of constant compound.

Before taking An Thien nuggets of An Thien treatment of stomach - duodenal ulcer (30 packs)

How to use

Take medicine at an empty stomach, 1 hour before every meal or before sleeping in the evening. Mix 1 pack into half a glass of water to form a homogeneous mixture before drinking.

Dosage

Adults and children over 12 years old

Treatment of duodenal ulcer, chronic gastritis

Use 2 packs (2g/time x 2 times/day) in the morning and before going to bed or 1 pack (1g/time x 4 times/day), drink 1 hour before meals and before bed, for 4-8 weeks, if needed can be used up to 12 weeks. The maximum dose of 8 packs (8g/day).

Treatment of benign stomach ulcers

Use 1 pack (1g/time x 4 times/day). Treatment continues until the ulcer heals completely. Usually require 6-8 weeks of treatment. If the patient is contaminated with Helicobacter pylori, the minimum treatment of H. pylori is required with metronidazol and amoxicillin, coordinating sucralfate and acid secretion (H2 histamine inhibitors or proton pump inhibitors).

Prevention of duodenal ulcer

Use 1 pack (1g/time x 2 times/day). Treatment does not last more than 6 months. Recurrent duodenal ulcer caused by H. pylori bacteria, to eliminate H. pylori, need a new session of sucralfate to combine antibiotics.

Prevention of stress ulcer

Use 1 pack (1g/time x 4 times/day). Maximum dose of 8g/day.

Prevention of stomach bleeding when ulcers due to stress

Use 1 pack (1g/time x 6 times/day). Maximum dose of 8g/day.

children 12 - 15 years old

Preventive ulcerative prophylaxis in children being treated for a strong treatment, treatment of duodenal ulcer - benign stomach

Use 1 pack (1g/time x 4 - 6 times/day).

Dacellular form of oral solution of 1g is not suitable for children from 1 month - 12 years old

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

If an overdose is indicated, it is necessary to monitor, and can be taken to the nearest medical facility for timely treatment.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Somastop An Thien, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive system: constipation.

Uncommon, 1/1000

Digestive system: dry mouth, nausea, diarrhea, bloating, indigestion.

skin: itching, erythema.

nerve: dizziness, dizziness, insomnia, drowsiness.

Other: back pain, headache.

Rare, 1/10000

The digestive system: the object in the stomach.

allergies: urticaria, shortness of breath, rhinoplasty, shortness of breath, rhinitis, larynx spasm, enlarged face.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Somastop An Thien is contraindicated in the following cases:

Hypersensitivity to sucralfate or any ingredient of the drug.

Precautions when used

Caution in patients with renal impairment due to the risk of increased aluminum concentration in serum, especially when used for a long time. In patients with severe renal impairment, only short -term used and need to be cautious when used. It is not recommended to use sucralfate in mitosis patients.

Small amount of aluminum is absorbed through the digestive tract and can be accumulated. Bone dysplasia, soft bone, brain disease, anemia has been reported in patients with renal impairment. Aluminum, phosphate, calcium, phosphatase concentration should be tested regularly with patients with kidney function impairment. It is not recommended to simultaneously use other aluminum preparations because of the increased risk of aluminum absorption and poisoning.

The ability to drive and operate machinery

Sucralfat can cause dizziness, dizziness, drowsiness on the nervous system. In case the patient has the above unwanted effects, must not drive, operate machinery, work on high or other jobs that can cause other dangers that require alertness and concentration.

Pregnancy

Classification for pregnancy according to FDA: Type B. has not determined the harmful effects on the fetus. Sucralfate absorbs very little through the digestive tract. However, during pregnancy, the drug should only be used in the case of essential.

Breastfeeding period

No sucralfat has not been determined in breast milk or not. If excreted in breast milk, the amount of sucralfate will also be very small, because the drug is absorbed into the body very little. Be cautious when using sucralfate in nursing women.

Drug interaction

can reduce the absorption of Digoxin, Quinidine, Fluoroquinolones, Tetracycline, Ketoconazole, Sulpiride, Levothyroxine, Phenytoin, Ranitidine, Cimetidine, Warfarin, Warfarin and Theophilline. Consider the medication distance for at least 2 hours between sucralfat and non -acid drugs that are simultaneously used.

Can create chelate complexes with aluminum increases the amount of aluminum absorption, increases the blood concentration in the blood when used simultaneously sucralfate with other preparations containing Al (for example, antacids containing Al, Citrate). If you need simultaneous use of antacids, recommend the 30 -minute gap between sucralfate and antacids.

Storage

Where dry, less than 30 ° C, avoid light.

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