Antacil drug 250mg Thai Nakorn Patana treat stomach and duodenal ulcer (25 blisters x 10 tablets)

Dosage form Box of 25 blisters x 10 tablets
Specifications Magnesium Trisilicate, Kaolin, Aluminum Hydroxide
Ingredient Nakorn

Ingredient

Composition information	Content
Magnesium trisilicate	350mg
Kaolin	50mg
Aluminum Hydroxide	250mg

Uses

Indications

Antacil drugs have anti -acid and ulcerative effect, used in the treatment of stomach ulcers, duodenum, reduced heartburn, indigestion due to peptic ulcer disease.

Pharmacokological

physiological, Magnesium is a cation in the intracellular. Magnesium reduces neurone stimulation and neurone transmission. Magnesium participates in many enamel reactions.

pharmacokinetic

absorption

Not absorbed through the gastrointestinal tract.

Metabolism

non -metabolic drugs in the body.

Elimination

Mainly excreted drugs through urine.

Before taking Antacil drug 250mg Thai Nakorn Patana treat stomach and duodenal ulcer (25 blisters x 10 tablets)

How to use

chew the tablet before swallowing with a little water. Drink after each meal 1 - 2 hours and before going to bed.

Dosage

Adults

Take 1-2 capsules at a time, chew carefully before swallowing with a little water, drink 3-4 times a day after each meal 1-2 hours and before going to bed or as instructed by the physician.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Overdose

Causes diarrhea due to the effect of magnesium salt dissolved on the intestinal tract.

Handling

Take medicine, consult a doctor.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Antacil drugs you may experience unwanted effects (ADR) such as:

Causes constipation or diarrhea due to the effect on the ionic ionic and magnesium ionic effect.

Causes excess acid due to increased acid secretion or fluid in the stomach.

Most side effects only occur when taking the drug for a long time.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Do not use Antacil for patients with renal impairment.

Precautions when used

antacid agents that can cause "acid recovery", which can increase acid secretion or fluid in the stomach. However, this effect is less clinically manifested, as it can be compensated by the buffer systems in antacids.

Hematomy phosphate: Hydroxyd aluminum long -term can cause hypothermia in patients with normal blood phosphate concentration when the amount of absorption phosphate is not enough. In more severe cases, hypoglycemia can lead to anorexia, depression, muscle weakness and bone foam.

For patients with impaired renal function: Pay special attention when using> 50meq Magnesi daily for patients with renal impairment. Due to reducing magnesium ionic ions, it can cause increased blood magnesium and toxic. About 5% to 20% of Magnesi salt can be absorbed by oral.

Gastrointestinal bleeding: Using aluminum hydroxyd must be cautious for patients with hemorrhage in the above gastrointestinal tract.

Hydroxyd aluminum long -term use in patients with renal impairment can lead to bone porous or severe bone porous. High aluminum concentration in tissue causes developing brain diseases and symptoms of bone porous. A small amount of aluminum is absorbed through the gastrointestinal tract and eliminated through the kidneys causing kidneys.

Aluminum combined with albumin and is transferred without passing through the membrane, so aluminum accumulates in the bone and bone foam may worsen when the patient's impaired renal function uses a large amount of aluminum.

The ability to drive and operate machinery

The drug hardly affects the ability to drive and operate machinery.

Pregnancy

Pregnant women should consult physicians before using antacids.

Breastfeeding period

For breastfeeding women, the harmful effects have been proven even though aluminum, calcium and magnesium can be secreted in milk, the concentration is not large enough to affect babies.

Medicinal interaction

Anti -acid drugs increase the gastric pH, change the disintegration, the dissolution, the ionization of some drugs and change the empty time of the stomach. Reducing the absorption of weak acidic drugs, which can lead to the effectiveness of the drug (for example: digoxin , phenytoin , chlorpromazin, izoniazide). Increasing the absorption of weak basic drugs, can be toxic or reactive (for example, pseudoephedrin, levodopa).

Adsorbent antacids or combined with other drugs on the surface reduces the bioavailability of these drugs (eg tetracyclin). Magnesi Trisilicat and Magnesi Hydroxyd have very high adsorption capacity, calcium carbonate and aluminum hydroxyd have medium adsorbent.

Antacids increases urine pH, affects the level of excretion of drugs, inhibits the excretion of base (e.g., quinidin, amphetamine) and enhances the excretion of acidic drugs (for example, salicylate).

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

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