Anyfen 300mg United drugs reduce symptoms of rheumatoid arthritis (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Dexibuprofen
Ingredient Cold, back pain, epidemic inflammation, arthritis, rheumatoid arthritis, sprain, musculoskeletal pain, Lumbar pain, inflammation, toothache

Ingredient

Composition information	Content
Dexibuprofen	300mg

Uses

Indications

Anyfen drugs are indicated to reduce the signs and symptoms of rheumatoid arthritis , rheumatoid arthritis easy to stimulate, osteoarthritis - joints, reduce mild pain and relieve pain due to normal colds, back pain , pain relief after surgery, Teeth, muscle pain, nerve pain, acute gout , dry arthritis, soft tissue lesions (sprains, bruising), and secondary pain in arthritis, tendonitis , tendonitis, epidemic inflammation.

Pharmacokic

Dexibuprofen is Ibuprofen's optical isomer S (+), which is nonsteroidal anti -inflammatory drugs. Like other nonsteroidal anti -inflammatory drugs, dexibuprofen has anti -inflammatory, analgesic and fever -reducing effects . The mechanism of action of the drug is Prostaglandin Synthetase inhibitors and thus preventing prostaglandin, thromboxan and other products of cyclooxygenase. Dexibuprofen is the safest drug in nonsteroidal anti -inflammatory drugs.

pharmacokinetics

Dexibuprofen is absorbed through the digestive tract, the maximum concentration of the drug achieved in plasma achieved after drinking from 1 to 2 hours. About 90 - 99% of the drug is connected to plasma proteins. Half life elimination of the drug is about 2 hours. Dexibuprofen is rapidly eliminated through urine (about 1% in constant form and about 14% in the form of a combination).

Before taking Anyfen 300mg United drugs reduce symptoms of rheumatoid arthritis (10 blisters x 10 tablets)

How to use

Take the tablet with a glass of water.

Dosage

Adults

Use 300mg of Dexibuprofen, 3-4 times a day. Maximum dose 1,200mg a day.

Children under 30kg of weight

Maximum dose of 300mg a day. Recommendation to use the smallest dose.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? If you have overdose, the following measures should be applied to increase elimination and inactivation of drugs: gastric lavage, vomiting, diuretic, drinking activated carbon or salt bleaching.

If severe: hemorrhage or blood transfusion. Because the drug causes acidosis and elimination in the urine, theoretically will benefit when transmitting alkaline and diuretic.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using anyfen you may experience unwanted effects (ADR) such as:

shock

rarely shock, should be monitored carefully. If any symptoms occur, the medication should be discontinued and properly treated.

Hematology

rarely occur platelet reduction , leukopenia, granulocytosis, hemolytic anemia, non -regenerated anemia, hemorrhage, allergic blessing, and hemoglobin. Should be monitored carefully, if any symptoms occur should stop taking the drug and conduct appropriate treatment.

digestive system

Gastrointestinal ulcer (with or no bleeding or perforation), esophageal damage, hemorrhage but no ulcers rarely occur. If any symptoms occur, treatment should be stopped. Sometimes, anorexia, nausea, vomiting, abdominal pain, indigestion, diarrhea, difficulty living, rarely occur thirst, stomatitis, abdominal distention, constipation

rarely occurs Stevens-Johnson syndrome and Lyell’s syndrome (poisoned epidermis). If occurred, treatment should be stopped.

liver

rarely jaundice and sometimes there is an increase in GOT, GPT, ALP and symptoms.

sensitive

rarely have bronchospasm , rash and eczema. Sometimes, rashes and itching may occur. If occurred, treatment should be stopped.

sensory system (sensory agency)

Rarely suffer from visual disorders (blurred, deaf), tinnitus and taste disorders. If occurred, treatment should be stopped.

Central nervous system

rarely cause meningitis due to viruses, headaches, nausea, vomiting, insomnia, fever and conscious disorders that may occur, should stop taking the drug and consult a doctor. Should pay special attention to systemic lupus erythematosus (SLE) and mixed connective tissue (MCTD).

circulatory system

rarely suffer from hypertension, reduced blood pressure and chest drums may occur.

Kidney

rarely occur acute renal failure , hypoglycemia, urinary tract, proteinuria, bun, hyperninery blood, hyperkalemia, if occurring should stop taking medication and conduct appropriate treatment. Can reduce the volume of urine, edema, can occur.

cardiovascular system

Heartbreaking heart failure in patients with heart function, high blood pressure , chest drums.

Other

Sometimes face edema, rarely have a fever, difficult to stay.

Notify the doctor the unwanted effects encountered in the use of the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

anti -contraindicated drugs in the following cases:

Patients with gastrointestinal ulcer .

Patients with severe hematological disorders.

Patients with severe liver disorders.

Patients with severe renal disorders.

Patients with severe blood pressure.

Patients with severe heart failure.

Patients with hypersensitivity to the ingredients of the drug.

Patients with asthma , bronchospasm when taking aspirin, or other sensitive reactions caused by aspirin or other nonsteroidal anti -inflammatory agents.

Be cautious when using anyfen for the following cases:

Patients with a history of gastrointestinal ulcer.

Patients with a history of blood disorders.

Patients with a history of liver and kidney failure.

Patient heart failure .

Patients with high blood pressure.

Patients with a history of hypersensitivity.

Patients with erythematosus lupus system (SLE) and mixed connective tissue (MCTD).

Patients with colon ulcer.

Patient stomach cancer .

Crohn's disease.

Old people, children, children.

Be cautious when used

Treatment with analgesic anti -inflammatory drugs is only symptomatic treatment. In case of use for chronic diseases should pay attention to the following cases:

When using dexibuprofen for long -term treatment should be checked periodically (blood formula, liver function, urine test). If the side effects occur, the dose should be reduced and stopped using the drug.

Note when treated with other drugs.

In case of use for acute diseases should pay attention to the following cases:

Be cautious when indicating dexibuprofen for cases of pain, severe fever, acute inflammation.

Should avoid long -term treatment with similar drugs.

Cause treatment.

In case of using drugs to treat flu disease , the treatment time within 5 days.

Should monitor the patient's condition and side effects. Because there may be excessive hypothermia, health depression, and special paralysis, especially for children with high fever, elderly or tuberculosis patients should be carefully monitored.

Dexibuprofen's anti -inflammatory effect may lose the symptoms and symptoms of infection, so it should be used with an appropriate antibiotic and monitoring during treatment.

Avoid using with other anti -inflammatory drugs.

To avoid side effects, the lowest dose should be used for children and healthy elderly.

The ability to drive and operate machinery

During the treatment with Dexibuprofen, the patient's reaction ability may be impaired if unwanted effects appear such as headache, conscious disorders. Therefore, it is necessary to be very cautious when driving and operating machinery. In case of using single -dose or dexuin doses in a short time, there is no special attention.

Pregnancy

so far, there are no adequate and controlled studies on the use of dexibuprofen in pregnant women, so they should only be used during pregnancy when really necessary.

Record other NSAIDs causing damage at the fetal circulation.

Studying fertility in mice at the end of the pregnancy period, recognizing dexibuprofen narrowing the arterioscleros.

Breastfeeding period

Dexibuprofen excreted in milk, Dexibuprofen is recommended not for nursing mothers.

Other special cases

Safety and effectiveness Dexibuprofen in children under 4 years old have not been set up.

Be cautious for patients who are prone to unwanted effects. Especially, the lowest dose should be effective for the elderly to weaken or lightweight.

Medicinal interaction

Precautions when used in combination with drugs of angiotensin transferring enzyme inhibitors because it can reduce hypertension effect.

Be cautious when used in combination with anticoagulant drugs Coumarin (warfarin) may increase the effect.

Be cautious when used in combination with aspirin because it can reduce the effects of Dexibuprofen and other NSAIDs.

Do not use in combination with methotrexate because of increased blood toxicity of methotrexate.

Be cautious when used in combination with Furosemid because it can reduce the effect. Patients should be monitored the signs of kidney failure.

Dexibuprofen reduces lithium clearance in the kidney and lithium concentration in plasma. Lithium toxic symptoms should be monitored when used with lithium.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children.

Other drugs

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