Apitim 5 DHG treatment for hypertension (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Amlodipine
Ingredient High blood pressure, angina

Ingredient

Composition information	Content
Amlodipine	5mg

Uses

Indications

apitim 5 treat hypertension, especially in patients with metabolic complications such as diabetes.

Stable prophylaxis treatment.

Pharmacokic

APITIM 5mg Anti -angina is mainly due to the relaxation of peripheral artery and cardinal reduction. The consumption of energy and oxygen needs of the heart muscle decreases because the drug does not cause reflexes of tachycardia. Amlodipine relaxes coronary artery (arteries and urine) in normal and anemic region leading to increased oxygen supply to the heart muscle.

pharmacokinetics

Birth of amlodipin when taking about 60 - 80% and not affected by food. Selling time is from 30-40 hours. Stable concentration in plasma reaches 7-8 days after taking the drug once a day. The drug metabolizes mainly through the liver. The metabolites are inactive and excreted through the urine. In people with liver failure, the dose should be reduced or prolonged the dosage.

Before taking Apitim 5 DHG treatment for hypertension (3 blisters x 10 tablets)

How to use

Use APITIM 5 by oral.

Dosage

depending on the response of each patient.

Starting dose: Take 5mg x 1 time/ day, then increase gradually.

Can increase the dose up to 10 mg x 1 time/ day.

No dose adjustment when combined with thiazid diuretics, beta blockers or enzyme inhibitors.

or as directed by the physician. Read the user manual carefully before use.

If you need more information, please consult your doctor. This drug is only used by a doctor.

What to do when overdose?

How to handle

Monitor cardiovascular disease with electrocardiograms and treat symptoms of effects on cardiovascular effects along with gastric lavage and active carbon drinking. If you need to adjust the electrolytes. In case of bradycardia and heart cucating, atropine intravenous injection, gluconate, isoprenalin or adrenalin or dopamine. For patients with a decrease in the volume of circulating the transmission of 0.9%sodium chloride solution, when a pacemaker is needed. In case of serious hypotension, intravenously, 0.9%sodium chloride solution, adrenalin. If not effective, use isoprenalin in combination with aminon.

What to do when forgetting 1 dose? However, if the time of relaxation with the next dose is too short, skip the forgotten dose and continue the APITIM 5 calendar. Do not double the dose to compensate for the missed dose.

Side Effects

When using Apitim 5 may experience side effects:

Common

Ancient edema (related to the dose), headache, dizziness, blushing and feeling of heat, fatigue, weakness, brushing chest, cramps, nausea, abdominal pain, indigestion, shortness of breath.

rarely

Excessive hypotension, tachycardia, chest pain, exterior, itching, muscle pain, joint pain, sleep disorders.

rarely

Magnetic collection, hyperplasia, urticaria, liver enzyme layer, hyperlem of blood glucose, confusion, diverse roses.

Notify the doctor with unwanted effects when using Apitim.

Warnings

Contraindicated

APITIM5 drug is contraindicated in the following cases:

Hypersensitivity to Dihydropyridin derivatives.

Do not use for people with untreated heart failure.

Precautions when used

impaired liver function, aortic stenosis, cardiac failure after acute myocardial infarction.

Pregnancy or lactation

Calcium channel blockers can inhibit early uterine contractions. However, the drug has no adverse effects during childbirth. The risk of oxygen deficiency must be taken into account if causing hypotension to the mother.

In experimental animals, calcium channel blockers can cause teratogenic bone deformities. Therefore, avoid using amlodipine for pregnant women, especially in the first 3 months of pregnancy.

There has been no notice to evaluate the accumulation of Amlodipin in breast milk, so consult a doctor when using the drug during breastfeeding.

The ability to drive and operate machinery

There is no document on the effect of Apitim 5 on driving and operating machinery. However, be careful because like other medications for hypertension, the drug can cause dizziness and dizziness.

Medicinal interaction

Anesthesia increases the effects of amlodipine and can make blood pressure more sharply.

Using lithium along with amlodipine can cause nerves, nausea, vomiting, diarrhea.

Non -steroid anti -inflammatory drugs, especially indomethacin, can reduce the effect of amlodipine.

Use highly connected drugs with plasma proteins (such as Coumarin, Hytantoin ...) with amlodipine and amlodipine also linked with protein, so the concentration of the above drugs in free (non -linked) form can change in serum.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

Expiry date: 36 months from the date of production.

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