ARBOL-100 Olive Healthcare drug used in blood calcium, parathyroidal reflection (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Alfacalcidol
Ingredient Osteoporosis, hypothyroidism, calcium deficiency, rickets

Ingredient

Composition information	Content
Alfacalcidol	1mcg

Uses

indications

ARBOL 100 drugs are indicated in the following cases:

Hyperaciaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaiaia heia when helping kidney, rickets or osteoporosis. Tri 1 alpha. Alfacalcidol is easily hydroxyl, at 25, by the microsom system of the liver, to form Calcitriol [1.25 - (OH) 2D3]. This is a metabolic substance that maintains normal calcium and phosphorus concentration in plasma by increasing the effectiveness of the absorption of minerals from the diet, in the small intestine and increasing the mobilization of calcium and phosphorus from the bone to the blood.

Reduce 1 alpha hydroxylation in the kidneys reduces production 1.25 - (OH) 2D3 endogenous. This causes mineral metabolic disorders found in a number of diseases, including kidney disease, hyperthyroidism, blood calcium in newborn babies and rickets depend on vitamin D. This can lead to unpredictable reduction of blood calcium, which can take a few weeks or a few months to recover. The main advantage of alfacalcidol is the faster start, which allows a more accurate titration of dosage. Therefore, lower blood calcium can occur for a few days after treatment.

pharmacokinetics

alfacalcidol absorb good through the gastrointestinal tract. Alfacalcidol and its metabolites rotate in the blood associated with specific alpha globulin. Alfacalcidol converts the liver to 1.25 - (OH) 2D3, which is a substance that regulates calcium and phosphorus concentration in serum.

The drug is excreted mainly through bile and feces, a small amount of cards excreted through urine.

Before taking ARBOL-100 Olive Healthcare drug used in blood calcium, parathyroidal reflection (3 blisters x 10 tablets)

How to use

ARBOL 100 drugs are taken orally.

Dosage

Take 1 capsule/time x 2 times/day or as recommended by your doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptoms

Symptoms may include anorexia, fatigue, nausea and vomiting, constipation or diarrhea, polyur, night urine, sweating, headache, thirst, drowsiness and dizziness and hypercalcemia.

Handling

Stop drugs, symptomatic treatment and support, drink plenty of water or infusion. If necessary, corticosteroids can be used or other drugs, especially diuretics increase calcium (such as: Furosemid and ethacrynic acid) to reduce calcium levels in serum. Can use artificial kidney dialysis or abdominal separation to release free calcium from the body

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using ARBOL 100, you may experience unwanted effects (ADR).

Unwanted effects of overdose symptoms include: anorexia, fatigue, nausea, vomiting, diarrhea, constipation, weight loss, sweating, headache, thirst, dizziness and increased calcium levels, blood phosphate and urine.

rarely occur

Renal calcium, itching, rash, urticaria.

Instructions on how to handle ADR

Notice immediately to the doctor or pharmacist when encountering unwanted effects of the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

ARBOL 100 drug contraindicated in the following cases:

Increased calcium, phosphate, plasma magnesium.

Do not use medication for patients with signs of vitamin D poisoning or a history of hypersensitivity to the effect of vitamin D.

Be cautious when used

alfacalcidol increases the absorption of calcium and phosphate in the intestine, so it is necessary to monitor the concentration of calcium and phosphorus, especially in patients with renal impairment.

Caution in patients with kidney stones.

The ability to drive and operate machinery

The drug has an unwanted effect that causes a dizzy headache, so be careful when driving and operating machinery,

Pregnancy

Animal research does not see any danger when taking the drug. However, only using alfacalcidol during pregnancy if treatment is necessary and no better replacement.

breastfeeding period

alfacalcidol is found in breast milk of mothers using alfacalcidol. This can affect the exchange of calcium in infants who breastfeed and stop breastfeeding should be considered.

Drug interaction

should not be treated simultaneously with cholestyramin or colestipol hydrochloride, as it can lead to reducing the absorption of Alfacalcidol in the intestine.

Excessive use of mineral oil can hinder the absorption of alfacalcidol in the intestine.

Simultaneous treatment of alfacalcidol with diuretic gums for those who are parathyroidism can lead to hypercalcemia. In that case, it is necessary to reduce the dose of alfacalcidol or stop using temporary alfacalcidol.

Do not simultaneously use alfacalcidol with phenobarbital and/or phenytoin (and may be with other drugs that cause liver enzymes) because these drugs can reduce alfacalcidol levels in plasma.

Do not simultaneously use alfacalcidol with corticosteroids because corticosteroids hinder the effect of alfacalcidol.

Do not simultaneously use alfacalcidol with cardiac glycosides because the toxicity of glycosides supports increased cardiac due to hypercalcemia, leading to arrhythmia.

Storage

Store in closed packaging, temperatures below 30 ° C, avoid moisture and avoid light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.