Arthrobic 15 mekophar medicine for osteoarthritis and rheumatitis (30 tablets)

Dosage form Box of 30 tablets
Specifications Meloxicam
Ingredient Osteoarthritis, joint spondylitis, rheumatoid arthritis, osteoarthritis

Ingredient

Composition information	Content
Meloxicam	15mg

Uses

indications

Arthrobic 15 drugs are indicated in the following cases:

Treatment of long -term symptoms of chronic inflammation in osteoarthritis pain (joint damage, osteoarthritis, rheumatoid arthritis, joint inflammation).

Pharmacokology

Meloxicam is an non -steroid anti -inflammatory drug (NSAID), Oxicam derivatives, with anti -inflammatory, analgesic and antipyretic effects. Meloxicam inhibits the synthesis of prostaglandin, intermediate substances that play an important role in the pathogenesis of inflammation, fever, pain.

Dynamic pharmacokinetics

Meloxicam well absorbed through the gastrointestinal tract, food very little affects the absorption. Meloxicam is metabolized almost entirely in the liver with the main catalyst of CYPC9 and a small part of CYP3A4, metabolites no longer active excreted mainly through urine and feces. A small amount of non -metabolic drugs excreted through urine (0.2%) and fertilizer (1.6%).

Before taking Arthrobic 15 mekophar medicine for osteoarthritis and rheumatitis (30 tablets)

How to use

Take oral use.

Dosage

Dosage: According to the doctor's instructions.

Adults:

Rheumatoid arthritis, joint spondylitis: 15mg/ day. When the longest treatment is in people with many risks of auxiliary complications, Lieu recommends 7.5mg/time/day.

Acute pain of osteoarthritis: 7.5 mg/time/day. When needed can increase the dose of 15 mg/day/day.

Maximum Meloxicam dose is recommended every day is 15mg.

Elderly people: The recommended dose is 7.5 mg/time/day.

Patients with liver failure, mild and moderate kidney failure without the need to adjust the dose.

Patients with dialysis dialysis: not more than 7.5 mg/day/day.

To minimize the unwanted effect of Meloxicam, the lowest dose should be used in the shortest possible time.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

If the overdose occurs, please immediately go to the nearest medical facility for medical staff to have appropriate treatment methods.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned.

Side Effects

When using Arthrobic 15, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: digestive disorders, nausea, vomiting, abdominal pain, constipation, bloating. diarrhea;

Blood: Anemia; skin: itching, skin rash; nerve: headache;

Systemic: edema.

Uncommon, 1/1000

Liver: Mild transaminase, bilirubin;

digestive: belching, esophagitis, stomach ulcers - duodenum, potential gastrointestinal bleeding; Blood: leukopenia, platelets;

Skin, mucous membranes: urticaria stomatitis; cardiovascular: Hypertension, brushing chest, blushing; kidney: increase creatinine and blood urea;

nerve: dizziness, tinnitus, drowsiness, ...

Rare, 1/10000

Colitis, gastrointestinal ulcers, duodenal, hepatitis, gastritis, increased skin sensitivity to light, diverse erythema, Stevens -Johnson syndrome, Lyell syndrome, bronchial asthma attacks.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

ARTHROBIC drug contraindicated in the following cases:

Hypersensitivity to one of the ingredients of the drug.

Patients with a history of allergies to aspirin or other nonsteroidal anti -inflammatory drugs.

Patients with symptoms of bronchial asthma, nasal polyps, nerve angiema or quincke edema, urticaria after taking aspirin or other nonsteroidal anti -inflammatory drugs.

Patients with stomach ulcers - duodenum progressive, stomach bleeding, brain bleeding.

Patients with severe liver failure, severe dialysis.

Children under 18 years old.

Be cautious when using

Stop taking the drug as soon as during treatment, there is an abnormal manifestation on the skin, mucosa or showing signs of ulcerative or gastrointestinal bleeding, rising liver function assessment parameters exceeding normal or prolonged increase.

Patients with a history of stomach - duodenal ulcer.

Patients are taking anticoagulants.

Patients with reduced blood flow to the kidneys, or hypoglycemia such as heart failure, nephrotic syndrome, cirrhosis, severe kidney disease, diuretics or large surgery are required to check the volume of urine and kidney function before using Meloxicam.

Elderly people with poor liver, kidney and heart function should not use Meloxicam.

The ability to drive and operate machinery

Caution.

Pregnancy

Contraindicated for pregnant women.

Lactation period

should not use meloxicam during breastfeeding. If you need to use medication for mothers, do not breastfeed.

Interactive drug

When combined Meloxicam with:

Other nonsteroidal drugs: increases the risk of stomach - duodenal ulcer.

Tclopidine oral blood clots, heparin, thrombolytic drugs: Bleeding risk.

warfarin: Increase bleeding.

Lithium: Increased blood lithium concentration.

methotrexate increases the toxicity of methotrexate on hematology system.

The IUD is the contraceptive effect of the IUD in the supply.

Diuretics may increase the risk of acute renal failure in dehydration patients. Furosemide and Thiazide: Reduce the diuretic effect of these drugs.

Antid for hypertension (such as A-commenergic inhibitors, enzyme inhibitors that switches angiotensin vasodilators): reduces vasodilation, lowering blood pressure.

Colestyramine: Reducing the absorption, increasing meloxicam elimination.

Cyclosporine: Increases the toxicity of the kidneys.

Storage

In a dry place, avoid light, the temperature does not exceed 30 ° C.

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