ASLEM injection solution 0.3mg/ml Vinphaco enhances immunity (1 blister x 10 tubes x 1ml)

Dosage form Box of 1 blister x 10 tubes x 1ml
Specifications Sodium chloride, glycin
Ingredient Vinphaco

Ingredient

Composition information	Content
Sodium chloride	9mg
Glycin	0.3ml

Uses

indications

ASLEM drugs are indicated in the following cases:

In the cancer department: Use with chemotherapy regimen or radiation therapy after tumor surgery (in liver, stomach, colorectal, bronchial, lungs, breasts) and with liver cancer without surgery, in order to extend the patient's life time. Funtumin has a non -specific immune effect on both physical immune response and immune response through cell intermediaries.

On the mutual immune response, Glycyl Funtumin enhances the blood circles (Jerne Cunningham).

On the cellular immune response, Glycyl Funtumin activates the phagocytic function of the macrophage, increases the shift of cell lymphocytes and the ability to recover to create Rosette E is inhibited by theophylin. In patients with colorectal cancer, Glycyl Funtumin stimulates T cells to increase the secretion of Cytokin Type 1 (IL - 2, IFN) and inhibit cytokin Type 2 (IL - 4, IL - 10).

Glycyl Funtumin stabilizes red blood cells and lysosome.

Glycyl Funtumin enhances the resistance to anti -vivo infections and in the experiment that causes peritonitis by antibiotic blue pus bacilli.

In random controlled clinical trial combined with chemotherapy regimen 5 - FU+ Folinic acid after surgery in colorectal cancer patients, the drug has the effect of restoring the quantity and functions of peripheral immune cells: Overseas CD3, CD4 and CD8, while increasing the ability to infect CD4 and CD8 cells into colorectal cancer organizations.

Clinical results monitoring using Aslem shows that on gastrointestinal cancers (stomach, mental, pancreatic, colorectal and liver cancer has surgical indications), the drug has the effect of prolonged life after surgery compared to non -drug use. Aslem has the effect of prolonging the life of patients with primary liver cancer without surgery compared to the group that only uses conventional treatments. On bronchial cancer, lungs, drugs increase the surgery rate of patients, while improving percentage of peripheral blood lymphocytes compared to the control group.

In the clinical trial, there is a control combination with a chemotherapy regimen after breast cancer surgery showing that the ASLEM treatment group tends to increase the number of leukocytes, lymphocytes and red blood cells during the first time using the drug. These values gradually decrease in the following treatments but still within normal physiological limits. There is an improvement in additional life after surgery and reduced recurrence in the group treated with drugs.

Monitoring patients with multiple infections, nail boils caused by Staphylococcus aureus need surgical intervention shows that combination of Glycyl Funtumin injections around the surrounding area is surgery in combination with antibiotics that allow to reduce the level of invasion and development of damage, increase the number of white blood cells and lymphocytes, shorten the time to use antibiotics.

Dynamic pharmacokinetics

have been studied on volunteers, using a single dose of 0.6 mg intramuscularly and intravenously, obtaining the following pharmacokinetic parameters:

After intramuscularly: cmax = 9.14 ng/ml; Tmax = 6.83 minutes; AUC = 289.59 (ng/ml x minutes).

After intravenous injection: cmax = 40.68 ng/ml; Tmax = 2 minutes; AUC = 320.45 (ng/ml x minutes).

Absolute intramuscularly abuse: 91.68%.

Before taking ASLEM injection solution 0.3mg/ml Vinphaco enhances immunity (1 blister x 10 tubes x 1ml)

How to use

intramuscularly, skin injection or intravenous injection.

There is no special requirement on drug treatment after use.

Dosage

as directed by the treating doctor.

Normal dose: 0.3 mg/time, 3 times/week immediately after surgery and during chemical or radiation treatment. To enhance the effectiveness of the drug, the time to use the drug should be pulled for at least 2 years.

Use with antibiotics in the treatment of surgical infections: 1 - 3 tubes/day in combination with specific antibiotics and surgical. Treatment period is from 2 to 10 days depending on the regression of damage.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? There are currently no reports on overdose during the circulation of ASLEM drugs.

If an overdose occurs, symptomatic support and treatment may be used. Actively monitor for timely management measures.

What to do when forgetting a dose?

Side Effects

When using Aslem, you may experience unwanted effects (ADR).

During the circulation of drugs on the market, no serious unwanted effect has been reported to the manufacturer and the National ADR monitoring center.

In clinical trials, some of the following unwanted effects are recorded: rash, urticaria, vomiting, nausea, constipation.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

ASLEM drug contraindicated in the following cases:

Sensitive to any ingredients of the drug.

Pregnant and lactating women.

Be cautious when using

be careful for patients with a history of allergies.

Because there is no enough data on the safety of drugs for children under 18 years old, as well as for patients with impaired liver and kidney function, it is necessary to consider the risk/benefit when using the drug for this object.

The ability to drive and operate machinery

There is no evidence of the effect of the drug on the ability to drive, operate machinery.

Pregnancy

There is no data on safety when using drugs on pregnant women. So avoid using drugs for this object.

breastfeeding period

There is no data on safety when using drugs in nursing women. So avoid using drugs for this object.

Interactive drug

There has been no recognition of ASLEM interaction with other drugs.

Cavalry

Due to the absence of studies on the correlation of the drug, not mixing this drug with other drugs.

Storage

In a dry place, temperatures below 300C, avoid light.

Other drugs

Disclaimer

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