Asosalic skin ointment 0.5mg/g Relek treatment of horn, dry skin (30g)

Dosage form Box x 30g
Specifications Betamethason dipropionate, salicylic acid
Ingredient Relek Farm Ltd. Skopje

Ingredient

Composition information	Content
Betamethason dipropionate	0.05%
Acid salicylic	3%

Uses

indications

Asosalic drug indicated in the following cases:

Treatment of keratinization and dry skin response to corticosteroids when the horny epithelium prevents the absorption of steroids. A glucocorticoid shows the full properties of corticosteroids and salicylic acid is a substance that works to peel off the horny skin.

Local salicylic acid is used to treat horny horns and peeling horn layers to help corticosteroids easily absorb.

With pharmacological doses, corticosteroids are prioritized for anti -inflammatory and immunosuppressive activity.

topical corticosteroids like betamethason, which is very effective in treating skin diseases because the drug has anti -inflammatory, anti -itching and vasoconstriction activity. However, because of the physiological, pharmacological and clinical effects of corticosteroids have not been well known, it is not possible to accurately determine the mechanism of this impact.

Dynamic pharmacokinetics

Salicylic acid only acts on the spot when applied on the skin.

Local corticosteroid absorption level depends on many factors including excipients, the integrity of epidermal barriers and the use of tape.

corticosteroids can be absorbed through normal skin. Inflamed skin and/or other diseases can increase the absorption of drugs.

Tapes increase the absorption of topical corticosteroids.

When absorbed through the skin, corticosteroids have similar pharmacokinetic data to the whole body. Corticosteroids associated with plasma proteins with different levels, first transformed through the liver and then excreted through the kidneys. Some topical corticosteroids and its metabolites can be excreted through the bile.

Before taking Asosalic skin ointment 0.5mg/g Relek treatment of horn, dry skin (30g)

How to use

Asosalic drug used on the skin.

Dosage

Adults:

One or twice daily. Apply a thin layer of ointment to the skin twice a day. The weekly dose should not exceed 60 g.

Children:

Using children only for 5 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Treatment: mainly symptomatic treatment. Acute corticosteroid syndrome is usually recovered. Treatment of electrical balance is necessary. If chronic toxicity, corticosteroids should be stopped gradually.

With preparations containing salicylic acid, prolonged overdose can cause Salicylate poisoning syndrome. Need symptomatic treatment. Need to quickly remove salicylat from the body. Sodium bicarbonate can be taken to alkalize urine and diuretic.

If you accidentally take the wrong medicine, the content of steroids in each type is very low, not enough to toxicity or if any, very little.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

Unwanted effects (ADR) when using Asosalic that you may encounter.

betamethasone + Salicylic acid used on the skin is generally good and rarely causes unwanted effects.

Continuous use for a long time can cause local skin atrophy, striped stripes and surface blood vessels, especially facial skin.

The following adverse effects have been reported when using betamethason on the spot, including: red, itching, irritation, dry skin, folliculitis, hair, acne rash, reduced skin pigmentation, dermatitis around the mouth, allergenic contact dermatitis.

The following unwanted effects may occur more often if the skin is closed: soaked skin, secondary infection, skin atrophy, skin message and sweating.

In addition, using prolonged salicylic acid can cause dermatitis.

When experiencing side effects of the drug, patients need to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

anti -contraindications in the following cases:

Blushing, acne, dermatitis around the mouth, anal itching, and genital organs. Bacteria that are not combined with appropriate antibiotics for treatment.

Be cautious when using

Do not use tape while taking the drug, because the effect of peeling the horny skin can increase the absorption of steroids.

Popular and body toxicity often occurs, especially when used on extended on wide damaged skin, folded or sealed skin area with polyethylene bandages. If used for children or used on facial areas, only use up to 5 days. Not long -term use for all patients without caring for age.

Local corticosteroids can be harmful in psoriasis for some reasons, including intact recurrence after tolerance, the risk of pustular psoriasis and systemic poisoning due to impaired skin protection function. Need to monitor patients closely.

If Asosalic is exposed to the eyes will be dangerous. Avoid contact with eyes and mucous membranes.

Betamethason dipropionate's body absorption may increase if applied to wide skin or skin that has been treated for prolonged or too many drugs. Be careful in these cases, especially when used for children and children.

If irritated, the medication must be stopped immediately and appropriate treatment.

Any adverse effects are reported when using systemic corticosteroids, including adrenal inhibition, can occur with topical corticosteroids, especially for children and children.

If the wound is not dry or there is an increase in skin irritation, it is necessary to stop taking this medication.

For children: Children are more likely to inhibit the hypothalamus-Yen-Than Kidney-Kidney and are more likely to have more body effects than adults when using the same dosage because the skin surface is larger than the body mass ratio.

Inhibit the lower pituitary, adrenal hill, Cushing syndrome, growth, no weight gain and increased intracranial pressure have been reported to children using local corticosteroids. Signs of adrenal insufficiency in children ”include lowering cortisol levels in plasma and non -response to ACTH stimulation.

Signs of increased intracranial pressure include fontanel, headache and visual enemies.

Pregnant women

Safety on topical corticosteroids for pregnant women have not been proven, only medication during pregnancy if the benefits are higher than the risk of harm to the fetus.

Do not overdose or take the medication for prolonged pregnancy.

It is not known whether or not the body can absorb the whole body enough to excrete into the breast milk or not, should stop breastfeeding or stop taking the drug, depending on the benefit of treatment for the mother.

Women who are breastfeeding

Do not know whether the drug is used on the spot can absorb the whole body enough to excrete in breast milk or not, should stop breastfeeding or stop taking the drug, depending on the benefit of treatment for the mother.

Drug interaction

drug interactions may affect the activity of the drug or cause side effects. Should notify the doctor or pharmacist a list of drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

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