Aspirin 100mg Traphaco prevents myocardial infarction, stroke (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Acetylsalicylic acid
Ingredient Traphaco

Ingredient

Composition informationContent
Acetylsalicylic acid100mg

Uses

indications

Aspirin 100 drugs are used for secondary myocardial infarction and stroke in the following cases:

  • There is a history of myocardial infarction (heart attack).
  • There is a history of stroke due to ischemia or stroke due to transient brain anemia (mild stroke).
  • Stable or unstable angina.

    • Heart surgery such as vascular shaping procedure or heart tubular surgery.

    Pharmacology

    Acetylsalicylic acid (aspirin) has an analgesic, cooling, anti -inflammatory effect when taking high doses. In low doses, the drug has the effect of inhibiting platelets, inhibiting thrombosis.

    Mechanism: Due to the inhibition of cyclooxygenase (COX), leading to the inhibition of the synthesis of thromboxan A2 is platelet collection.

    Platelets are non-nuclear cells, unable to synthesize new COX, so aspirin inhibits unfavorable platelet collection, this effect lasts the life of platelets (7-10 days).

    The inhibitory effect does not decrease when prolonged treatment and emzyme activity begins to be restored after stopping 24 - 48 hours. Aspirin extends the average bleeding time of about 50 -100%.

    Dynamic pharmacokinetics

    When taken, aspirin is quickly absorbed from the digestive tract. However, a large amount of aspirin is hydrolyzed into salicylic acid right in the intestinal wall.

    aspirin and salicylic acid metabolites are strongly linked to plasma proteins, mainly albumin and are quickly distributed into all parts of the body. The distribution of aspirin is 0.16 l/kg.

    Salicylic acid is mainly cleared in the liver glycine and complex glucuronic acid.

    Salicylic acid elimination time depends on the dose, limited by the liver enzyme capacity. The sale time lasts about 2-3 h when low doses (75-160 mg).

    Salicylic acid and its metabolites are mainly excreted through the kidneys, the amount of excretion increases according to the dose and dependent pH.

    Before taking Aspirin 100mg Traphaco prevents myocardial infarction, stroke (3 blisters x 10 tablets)

    How to use

    Aspirin 100 oral.

    Take whole tablets, do not break or chew the medicine before taking.

    Dosage

    Common dose: Take 1 capsule a day after meals, long -term use.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

    If the amount of Aspirin accumulates in the patient's body is relatively large (Salicylate concentration in plasma exceeds 500 mg/ml for adults, 350 mg/ml for children under 5 years old), patients can convend and coma.

    Salicylate overdose treatment includes: limiting aspirin's absorption into the blood by causing vomiting or gastric lavage, active carbon.

    Monitor and support the necessary functions for life. Causing the urinary tract with alkalinization of urine to increase salicylate excretion. In some serious cases, patients need to be transmitted to blood, hemolytic, peritoneal clinical.

    What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

    Side Effects

    When using aspirin 100, you may experience unwanted effects (ADR).

    The unwanted frequency of aspirin depends on the dose.

    Common, ADR> 1/100:

  • No report.
  • No report.

    • Rare, 1/1000

  • No report.

    • Very rare, ADR

    When using aspirin - 100 with low doses of 100 mg/day for a long time, it rarely has the following unwanted effects:

  • Digestive: gastric ulcer.
  • Skin and subcutaneous tissue: urticaria, allergic skin.
    • blood vessels: prolong bleeding time, increase the risk of bleeding.

    Instructions on how to handle ADR:

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Aspirin 100 contraindicated in the following cases:

  • Sensitive to any ingredients of the drug.

    • People with bleeding, thrombocytopenia, dengue fever, liver failure or severe kidney failure.

    Be cautious when using

    consult your doctor in the following cases:

  • There is a history of asthma.

    • History of allergies to aspirin or other salicylate derivatives.

    Stomach ulcers or a history of stomach ulcer.

  • Bleeding disorders (bleeding disease, liver disease or vitamin K deficiency).

    • History of stroke due to cerebral hemorrhage (due to broken brain vessels).

  • impaired liver and kidney function.
  • uncontrolled hypertension.

    • Women who are menstruation.

    The ability to drive and operate machinery

    No report.

    Pregnancy

    Do not use aspirin for the last 3 months of instead. In some necessary cases, it must be used as directed by the doctor, closely monitoring during use.

    breastfeeding period

    Aspirin is in breast milk, but with a very low risk of treatment for harmful effects in breastfeeding babies.

    Drug interaction

    simultaneously used with aspirin reduces the concentration of indomethacin, naproxen and fenoprofen.

    Interaction with warfarin increases the risk of bleeding.

    Interaction with methotrexate, sulphonylurea blood glucose, phenytoin, valproic acid increases the concentration of these drugs in serum and increases toxicity.

    Storage

    In a dry place, the temperature does not exceed 30 ° C, avoiding light.

    Other drugs

    Disclaimer

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    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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