Aspirin MKP 81 Mekophar prevents myocardial infarction, stroke (10 blisters x 10 tablets)

Dosage form Box of 10 blisters x 10 tablets
Specifications Acetylsalicylic acid
Ingredient Stroke, psoriasis, thrombosis

Ingredient

Composition information	Content
Acetylsalicylic acid	81mg

Uses

indications

Aspirin MKP 81 is indicated in the following cases:

Secondary prevention of myocardial infarction and stroke in patients with a history of these diseases.

Dynamic pharmacokinetics

acetylsalicylic acid (aspirin) is quickly absorbed from the digestive tract, part of acetylsalicylic acid is hydrolyzed into salicylate in the intestinal wall. After the circulation, the acetylsalicylic acid part is attached to the plasma protein at the rate of 80 - 90% and is widely distributed.

salicylate is cleared mainly in the liver. Salicylate is also eliminated in the form of unchanged urine, the amount of excretion increases according to the dose and dropped through the urine, excreted through the kidneys related to glomerular filtration processes, actively excreted through the renal tubules and passive reabsorption through the renal tubules. Salicylate can be eliminated through hemorrhage.

Before taking Aspirin MKP 81 Mekophar prevents myocardial infarction, stroke (10 blisters x 10 tablets)

How to use

Drink whole tablets, do not chew or crush out.

Dosage

use the dose as directed by the doctor.

Recommended dose:

Secondary prevention of myocardial infarction and stroke:

Take 1 - 2 capsules/day.

Pain relief:

Adults and children over 12 years: 4 - 6 capsules/time x 4 - 6 times/day. Do not use more than 3 g/day.

Children: 50 mg/kg/day, divided 4-6 times, but indicated very limited due to Reye syndrome risk.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Salicylate overdose treatment includes:

Clean the stomach by causing vomiting (pay attention to not inhale) or gastric lavage, drinking activated carbon. Monitor and support the necessary functions for life. High fever treatment; Infusion, electrolytes, acid -base imbalance; Treatment of cetone accumulation; Keep the concentration of suitable blood glucose.

Monitor sericylate serum levels until it is clear that the concentration is decreasing to the point of non -toxic. In addition, it is necessary to monitor for a long time if the overdose is large, because the absorption can last.

Causes the urethra with alkalinization of urine to increase salicylate excretion. However, oral bicarbonate should not be used, as it can increase the absorption of salicylate. If acetazolamide is used, it is necessary to carefully consider the risk of serious metabolic acid infection and Salicylate poisoning (caused by increased salicylate penetration into the brain due to metabolic acid infection).

Perform blood transfusion, hematoma, peritoneal clinical, if needed when overdose is serious.

Monitor pulmonary edema, convulsions and appropriate therapy if needed.

Blood transfusion or use vitamin K if needed to treat bleeding.

If the overdose occurs, it is recommended to go to the nearest medical facility for medical staff to have treatment methods.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Aspirin MKP 81, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: Nausea, vomiting, indigestion, discomfort in the epigastric, heartburn, stomach pain, stomach ulcers.

Body: Anaphylaxis, fatigue, rash, urticaria, muscle weakness, shortness of breath. blood: Hemolytic anemia.

Uncommon, 1/1000

TKTW: insomnia, restlessness, irritability.

blood: iron deficiency, hidden bleeding, prolonged bleeding time, leukopenia, thrombocytopenia, anemia.

Metabolism, urinary: toxic liver, impaired renal function.

Respiratory: Bronchospasm.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Aspirin MKP 81 contraindicated in the following cases:

Cam is with one of the ingredients of the drug.

Patients who have asthma, rhinitis or urticaritis when taking aspirin or other nonsteroidal anti -inflammatory drugs before.

Patients with a history of asthma.

People with bleeding, thrombocytopenia, stomach or duodenal ulcer are active, medium and severe heart failure, liver failure, kidney failure.

Be cautious when using

Need to reduce the dose at the elderly because it is likely to be poisoned by aspirin.

Do not combine aspirin with nonsteroidal anti -inflammatory drugs and glucocorticoids.

When treated simultaneously with anticoagulants or when there is a risk of other bleeding.

When used for children because of Reye syndrome.

When treating people with mild heart failure, kidney disease or liver disease, especially when used simultaneously with diuretics, it is necessary to carefully consider the risk of water retention and the risk of reducing kidney function.

Be cautious when used for train drivers or operating engine.

The ability to drive and operate machinery

Caution when used for train drivers or operating engine.

pregnancy

must not use aspirin in the last 3 months of pregnancy.

The period of breastfeeding

can take the drug because at the normal dose of Aspirin, there is very little risk of harmful effects in breastfed babies. Be cautious when taking medicine for breastfeeding women.

Interactive drug

reduces the concentration of indomethacin, naproxen and fenoprofen.

Increases the risk of bleeding for warfarin.

Increases methotrexate levels, sulphonylurea hypoglycemic drugs, phenytoin, serum valproic acid and toxicity.

Reduces the effect of urinary urinary acid medications such as probenecid and sulphinPyrazole.

Storage

The dry place (moisture Mekophar Pharmaceutical - Pharmaceutical Company was established in 1975, called the Central Pharmaceutical Enterprise 24, a member unit of Vietnam Pharmaceutical Corporation. In 2001, the company officially changed its name to Mekophar Pharmaceutical - Pharmaceutical Joint Stock Company. Mekophar's development orientation is to invest in research and development, especially research to put into production of new high quality products, appropriate prices, build new pharmaceutical production lines that meet GMP-WHO standards, increase capital for production and business activities, ensure and improve product quality of international standards that have been affirmed.

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