Atiferole oral solution 800mg/15ml An Thien treats iron deficiency and anemia

Dosage form Oral solution
Specifications Box
Ingredient Succinylate protein iron

Ingredient

Thành phần cho 15ml

Composition information	Content
Succinylate protein iron	800mg

Uses

Indications

Atiferole oral solution are indicated in the following cases:

iron deficiency and iron deficiency anemia.

ATC code: B03AB09.

Atiferole belongs to an Anti -Anemia drug containing iron ion to treat iron deficiency. Thanks to the soluble properties, Succinylate iron is precipitated in the stomach acid environment, so the iron atom is guaranteed. The precipitate is then dissolved in an alkaline pH environment in the duodenum so that the iron is absorbed into the intestinal mucosa, while the protein molecules are digested by the pancreatic protease enzyme.

Dynamic pharmacokinetics

cannot conduct common pharmacokinetics studies for iron complexes because with Succinylate protein complex, protein molecules that are digested by gastrointestinal fluids and iron are absorbed by the body. Under normal conditions, iron loss rarely occurs. Most iron is excreted through menstruation and a small amount is eliminated through bile, sweat and dead skin.

Before taking Atiferole oral solution 800mg/15ml An Thien treats iron deficiency and anemia

How to use

take medicine before meals.

Daily dose can be divided into several times or only one -time use.

The drug can be taken whole or diluted with a moderate amount of water.

Duration of treatment: Continuous treatment until the iron reserves in the body return to normal level (usually 2-3 months).

Dosage

Adults: 15 - 30 ml/day (equivalent to 40 - 80 mg of iron (Fe3+)/day, or according to the guidance of the treating doctor.

Children: 1.5 ml/kg/day (equivalent to 4 mg of iron/kg/day), or according to the guidance of the treating doctor.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Handling: Causing vomiting immediately, then, if necessary, the stomach must be conducted and combined with other appropriate supportive therapies. In addition, if necessary, use the agents capable of creating chelate complexes with iron such as DesferrioMine.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Atiferole, you may experience unwanted effects (ADR) such as:

Gastrointestinal disorders such as diarrhea, constipation, nausea and epigastric pain are rarely occurring, or more at the highest dose. These unwanted effects will decrease when the dose decreases and stop treatment. Iron preparations can cause discoloration to black or dark gray.

Instructions on how to handle ADR:

Notify the physician the unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Atiferole oral solution in the following cases:

Hypersensitivity to any ingredients of the drug.

Patients with iron cell syndrome.

Patients with hemolytic anemia or anemia, anemia due to iron absorption disorders (anemia due to loss of iron function).

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Any disease that can be due to iron deficiency or anemia due to iron deficiency must be firmly identified and treated to the end.

This drug contains protein in the form of milk. Therefore, be careful when taking the drug for patients with non -tolerance of milk protein, as there may be allergic reactions.

Duration of treatment should not last more than 6 months except for prolonged bleeding, menorrhagia and pregnancy.

Outmut warning

The drug contains sodium benzoate, which can increase the risk of jaundice and yellow eyes in newborns (4 weeks of age or less).

The drug contains sorbitol, sucralose, patients with rare genetic disorders such as galactose intolerance, lapp lactase deficiency, glucose-galactose absorption disorders or enzyme deficiency sucrase-isomaltase should not be used.

The drug contains propylene glycol, patients with liver or kidney disease without this drug unless there is a doctor's recommendation. The treatment doctor may have to take some auxiliary tests during the time the patient takes this medication. If a child is under 5 years old, consult a doctor or pharmacist before giving children the drug, especially when the child is given other drugs containing propylene glycol or alcohol.

In 15 ml of preparations containing 3000 mg of white sugar, it is necessary to be careful when used for people with diabetes.

The effect of the drug on driving and operating machinery

The drug does not affect the ability to drive and operate machinery.

Use drugs for women during pregnancy and lactation

There is no special warning for pregnant and lactating women. In fact, Atiferole is indicated for treatment of iron deficiency that can occur in these cases.

Model interactions

iron can disturb the absorption as well as affect the bioavailability of tetracycline, biphosphonate, quinolone antibiotics, penicillamine, thyroxine, levodopa, carbidopa, alpha-methyldopa. Aciferole should be used 2 hours before or after using the above drugs.

Iron absorption can increase when used simultaneously atferole with over 200 mg of ascorbic acid or decrease when used simultaneously with antacids. To minimize the ability to interact should use Atiferole 2 hours before or after using these drugs.

There is no report on pharmacological interaction when using atiferole simultaneously with antihistamine H2. When used simultaneously with chlorpheniramine can slow down the response of iron therapy.

taboo

iron -containing complexes (such as phosphate, phytate and oxalates) contained in a variety of vegetables, milk, coffee and tea capable of inhibiting iron absorption. Aciferole should be used 2 hours before or after using the above foods and drinks.

Patients should notify the doctor or pharmacist a list of the drugs and functional foods you are using. Do not use or increase or decrease the dose of the drug without the guidance of a doctor.

Storage

Leave a cool place, avoid light, temperature below 30⁰C.

To be out of reach of children, read the user manual carefully before use.

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