Atiro cough Atussin United supports reducing cough symptoms (30ml)

Dosage form Bottle x 30ml
Specifications Sodium citrate, dextromethorfan, chlorphenamine, phenylpropanolamine, ammonium chloride, glyceryl guaiacolate
Ingredient United

Ingredient

Composition information	Content
Sodium citrate	133mg
Dextromethorfan	5mg
Chlorphenamin	1.33mg
Phenylpropanolamin	8.3mg
Ammonium chloride	50mg
Glyceryl Guaiacolate	50mg

Uses

indications

Atussin is indicated in the following cases:

Treatment reduces symptoms of colds, influenza, tuberculosis, bronchitis, pertussis, measles, pneumonia, pneumonia, bronchiomorphism, sore throat, laryngitis, trachea, bronchitis, irritated pleura, inhalation of irritants, cigarette smoke and cough with central origin.

Pharmacokology

Dextromethorphan HBr

Dextromethorphan HBr is a cough reduction drug that works on cough center in the brain. Dextromethorphan is most effective in the treatment of chronic cough, cough without phlegm. With the treatment dose, the anti -cough effect of the drug lasts 5 - 6 hours.

chlorpheniramine maleat

Chlorpheniramine is a antihistamine with very little sedative effects. Like most other antihistamines, chlorpheniramine also has side effects against acetylcholin but this effect is much different between individuals. The antihistamine antihistamine effect of chlorpheniramine through the block of the h1 receptor of the acting cells.

Dames

sodium citrate has a moisturizing properties and plays a role in maintaining pH.

glyceryl guaiacolate makes long talks by reducing the viscosity of mucus.

Pharmacokinetics

Dextromethorphan HBr

Dextromethorphan is quickly absorbed through the gastrointestinal tract and works within 15 - 30 minutes after drinking, lasting 6-8 hours. The drug is metabolized in the liver and excreted through the urine in the form of constant and Demethyl metabolites, among them dextromethorphan also has a slight cough reduction effect.

chlorpheniramine maleat

chlorpheniramine maleate absorbs well when drinking and appears in plasma for 30-60 minutes. Plasma peak concentration reaches 2.5 to 6 hours after drinking. Low bioavailability reaches 25 - 50%.

About 70% of the drug during the circulation is linked to the protein. The distribution volume is about 3.5 liters/kg (adults) and 7 - 10 liters/kg (children). The drug is excreted mainly in urine in the form of constant or metabolic, the excretion depends on the pH and the urine flow. Only a small amount is seen in the feces. The sale time is 12-15 hours.

Dames

sodium citrate is absorbed and converted into sodium bicarbonate.

glyceryl Guaiacolate is absorbed through the gastrointestinal tract. It is metabolized and excreted in urine.

Before taking Atiro cough Atussin United supports reducing cough symptoms (30ml)

How to use

oral medication.

Dosage

Take every 6 to 8 hours or as instructed by a physician.

2 - 6 years old: 5 ml (1 teaspoon).

7 - 12 years: 10ml (2 teaspoons).

Adults and children over 12 years: 15 ml (3 teaspoons).

Children under 2 years of age: consult a doctor before use.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when using overdose?

Treatment: Support, use Naloxone 2 mg intravenously, for repeating the total dose of 10 mg if necessary.

The overdose symptom of chlorpheniramine includes drowsiness, central nervous stimulation, seizure, apnea, convulsions, anti -secretion effects Acetylcholine, hypertonic reaction and cardiovascular collapse, arrhythmia.

Symptomatic and support treatment; Stomach or vomiting with ipecacuanha syrup; Then use activated carbon and bleach to limit absorption. In the case of hypotension and arrhythmia, it should be actively treated. Diazepam or intravenous phenytoin may be helpful to treat convulsions. Can blood transfusion in heavy cases.

What to do when you forget 1 dose? If it is nearly time to take the next dose, skip the forgotten dose and take medicine at the next recommended dose. Do not take double dose to compensate for the forgotten dose.

Side Effects

When using Atussin, you may experience unwanted effects (ADR).

Fatigue, dizziness, headache, tachycardia, nausea, vomiting, diarrhea, redness, urticaria, sleeping chicken, sedation, dry mouth.

Instructions on how to handle ADR

Please inform your doctor unwanted effects when taking the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Patients who are sensitive to the ingredients of the drug or are using monoamine oxidase inhibitors.

Patients with acute asthma attacks, narrow -angle glaucomes, stomach ulcers, pyloric - duodenum and urine stasis due to urethra - prostate disorders.

Be cautious when using

Patients with coughs have too many talks, chronic coughs in smokers, asthma, pulmonary overflow, respiratory decline.

Use dextromethorphan related to histamine release and should be cautious for children with allergies.

Abuse and dependence on dextromethorphan may occur (though rare), especially due to prolonged high doses.

The ability to drive and operate machinery

Do not control the vehicle, machinery or other means of transport when taking the drug because the drug can cause sleepiness, loss of agility.

Pregnancy

consult your doctor before use.

Breastfeeding period

Women who are breastfeeding should not use Atussin.

Drug interaction

Monoamine oxidase inhibitors (IMAO) and 3 -round antidepressants can be prolonged, increasing anticholinergic effects and sedative effects of antihistamine drugs.

Storage

Store in a dry place, the temperature does not exceed 30 ° C, avoiding light.

To be out of reach of children.

Other drugs

Disclaimer

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