Ato cough cough Atussin United supports reducing cough symptoms (60ml)

Dosage form Bottle
Specifications Dextromethorphan, chlorpheniramine, sodium citrate, ammonium chloride, glyceryl Guaiacolate
Ingredient United

Ingredient

Composition informationContent
Dextromethorphan5mg
Chlorpheniramine1.33mg
Sodium citrate133mg
Ammonium chloride50mg
Glyceryl Guaiacolate50mg

Uses

Indications

Siro Atussin is designated in the following cases:

Reduce symptoms of colds, influenza, tuberculosis, bronchitis, pertussis, measles, pneumonia, pneumonia - bronchial, sore throat, laryngitis, tracheitis, bronchitis, irritated pleura, inhalation of irritants, cigarette smoke and they have a central origin.

Pharmacokology

Dextromethorphan HBr

Dextromethorphan HBr is a cough reduction drug that works on the cough center in the brain, dextromethorphan is most effective in the treatment of chronic cough, cough without phlegm. With the treatment dose, the anti -cough effect of the drug lasts 5 - 6 hours.

chlorpheniramine maleaty

chlorpheniramine is a histamine resistant with very little sedative effects. Like most other antihistamines, chlorpheniramine also has side effects against acetylcholin secretion, but this effect varies greatly among individuals. The antihistamine antihistamine effect of chlorpheniramine through the block of the h1 receptor of the acting cells.

The substances of Dam

sodium citrate has a moisturizing properties and plays a role in maintaining pH. Glyceryl Guaiacolate makes long talks by reducing the viscosity of mucus.

Pharmacokinetics

Dextromethorphan HBr

Dextromethorphan is quickly absorbed through the gastrointestinal tract and works within 15 - 30 minutes after drinking, lasting 6-8 hours. The drug is metabolized in the liver and excreted through the urine in the form of constant and Demethyl metabolites, among them the Dexorophan also has a slight cough reduction effect.

chlorpheniramine maleaty

Chlorpheniramine Maleate absorbs well when taken and appears in plasma for 30-60 minutes. Plasma peak concentration reaches 2.5 to 6 hours after drinking. Low biological use, reaching 25-50%. About 70% of the drug during the circulation associated with the protein. The distribution volume is about 3.5l/kg (adults) and 7 - 10l/kg (children). The drug is excreted mainly in urine in the form of constant or metabolic, the excretion depends on the pH and the urine flow. Only a small amount is seen in the stool. The sale time is 12 - 15 hours.

The substances of Dam

sodium citrate is absorbed and converted into sodium bicarbonate. Glyceryl Guaiacolate is absorbed through the gastrointestinal tract. It is metabolized and excreted in urine.

Before taking Ato cough cough Atussin United supports reducing cough symptoms (60ml)

How to use

Take oral use.

Dosage

Take every 6 to 8 hours or as instructed by a physician.

Children from 2 - 6 years old

Take 5ml (1 teaspoon).

Children from 7 to 12 years old

Take 10ml (2 teaspoons).

adults and children over 12 years old

Take 15ml (3 teaspoons).

children under 2 years old

consult your doctor before use.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Treatment: Support, use Naloxone 2mg intravenously, for repeating the total dose of 10mg if needed.

The overdose symptom of chlorpheniramine includes drowsiness, central nervous stimulation, seizure, apnea, convulsions, anti -secretion effects Acetylcholine, hypertonic reaction and cardiovascular collapse, arrhythmia. Symptomatic and support treatment; Stomach or vomiting with ipecacuanha syrup, then use activated carbon and bleach to limit absorption. In the case of hypotension and arrhythmia, it should be actively treated. Diazepam or intravenous phenytoin may be useful to treat convulsions.

Can transferred blood in severe cases.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using the Ato Atussin, you may experience unwanted effects (ADR).

Fatigue, dizziness, headache, tachycardia, nausea, vomiting, diarrhea, redness, urticaria, sleeping chicken, sedation, dry mouth.

Please notify your doctor the unwanted effects when taking the drug.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

ATussin Siro drugs in the following cases:

  • Patients who are sensitive to the ingredients of the drug or are using monoamine oxidase inhibitors.

    Caution when using

    Caution should be used when using the ATussin syrup for patients with coughs with too much phlegm, they are chronic in smokers, asthma, pulmonary overflow, respiratory impairment.

    Using dextromethorphan is related to histamine release and should be cautious with children with allergies.

    Abuse and dependence on dextromethorphan, can occur (though rare), especially due to prolonged high doses.

    The ability to drive and operate machinery

    affect the ability to drive and operate machinery: Do not control vehicles, machines, or other vehicles when taking the drug because the drug can cause sleepiness, loss of agility.

    Pregnancy

    consult your doctor before use.

    Breastfeeding period

    Medicinal interaction

    Monoamine oxidase inhibitors (IMAO) and 3 -round antidepressants can be prolonged, increasing anticholinergic effects and sedative effects of antihistamine drugs.

    • Storage

    Leave a cool place, avoid light, temperature below 30⁰C.

    To be out of reach of children.

    Other drugs

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