Ausbiobone BiPharm medicine treats mild and average knee osteoarthritis symptoms (60 tablets)
Dosage form Hard capsules
Specifications Box of 5 blisters x 12 tablets
Ingredient Glucosamine Sulfate-Potassium Chloride Complex, Chondroitin Sulfate, Manganese Gluconate
Indication Knee osteoarthritis
Contraindication Pregnancy, food allergies, drug allergies
Ingredient
| Composition information | Content |
| Glucosamine sulfate-potassium chloride complex | 500mg |
| Chondroitin sulfate | 11.11mg |
| Manganese Gluconate | 45.5mg |
Uses
Indications
Ausbiobone is indicated in the following cases:
Pharmacy
Glucosamine is a natural amino-monosaccharide produced in the body. It is one of the main substrates used in the biological synthesis of macro molecules of articular cartilage, such as glycosaminoglycans, protooglycans and hyaluronic acid. It plays an important role in the formation and restoration of cartilage. Unlike prostaglandin inhibitors that are related to joint destruction in osteoarthritis, glucosamine sulfate increases the synthesis of protooglycans in human cartilage culture experiments, cartilage cells are isolated from the cartilage organization of degenerated joints, and can lead to disease change. It has anti -inflammatory and effective effects on arthritis in animal models.
chondroitin is a blocking agent of proteoglycan molecules found in cartilage tissue. Chondroitine sulfate has an effect on the formation of new cartilage substrate by stimulating cartilage cell metabolism and collagen and proteoglycan synthesis. Chondroitin Sulfate has also been recorded as inhibiting Elactase and Hyaluronidase enzymes. High concentration of white blood cell enzyme is replaced in the blood and joints of the patient with rheumatism. Chondroitin Sulfate also stimulates Hyaluronic Acid's coincidence by epidemic cells. As a result, the viscosity is improved and the amount of animal substance returns to normal.
Manganese has anti -inflammatory properties: Research shows that the use of manganese has an opposite relationship with the risk of rheumatism in women.
pharmacokinetic
glucosamine is well absorbed after drinking. Glucosamine has oral bioavailability of about 25-28%, the sale time is about 30 minutes, closely combined with plasma proteins and glucosamine in the form of free concentrated in articular cartilage.
chondroitin sulphate is eliminated largely through urine. Oral bioavailability is 7 - 12%, plasma concentration reaches the maximum after about 190 minutes and the sale time is 6 hours.
Manganese is discharged through urine, feces, and bile. The absorption in long -term manganese users is 30-50% lower than those who do not use.
Before taking Ausbiobone BiPharm medicine treats mild and average knee osteoarthritis symptoms (60 tablets)
How to use
Take for oral after meals.
Dosage
Take 2 capsules/time, 2-3 times/day, or as directed by the doctor. Time to use the drug depending on the patient, at least use continuously for 2 to 3 months to ensure the effectiveness of treatment.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose? If this phenomenon should stop taking the drug and wait for all these symptoms before using the medication at the right dose.
What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
Rarely side effects when using Ausbiobone, if any, are usually digestive disorders: black stool, diarrhea or constipation.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Ausbiobone drug is contraindicated in the following cases:
Pregnant women, nursing women, children, adolescents under 18 years of age because there is no data on safety and effectiveness.
Caution when using
Caution and please read the instructions carefully before use.
Be cautious when used from seafood
Be cautious when used contains hydroxybenzoates
Each tablet contains 64.6 mg of potassium (125mg potassium chloride). Patients should consult a doctor before using the drug if you are suffering from kidney disease or are taking cardiovascular medications or blood pressure.
To far away from Ausbiobone from the reach of children.
If you need more information, please consult your doctor. Notify the doctor the side effects encountered when using the drug.
The ability to drive and operate machinery
Not yet seen.
Pregnancy and lactation
should not be used.
Drug interaction
Not yet seen.
Storage
Store at a temperature of less than 25 ° C in a hot and dry place and light. Avoid moisture.
To be out of reach of children.
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