Axcel Fungicort Cream to treat dermatitis, skin allergies (15g)

Dosage form Tube
Specifications Miconazole nitrate, hydrocortisone
Ingredient Axcel

Ingredient

Composition information	Content
Miconazole nitrate	2%
Hydrocortisone	1%

Uses

Indications

Axcel fungicort cream 15 g is indicated for treating inflammation, skin allergies that respond to glucocorticoid, accompanied by fungal infections on the skin surface.

Pharmacokological

Miconazole is an antifungal drug belonging to the imidazol group, which affects the synthesis of ergosterol and thus changes the absorbency of the cell membrane of sensitive fungi strains. The drug has the effect of killing Trichophyton, Epidermophytes, microsporum, Candida, Cryptococcus and Aspergilus.

Hydrocortisone is a glucocorticoid that has anti -inflammatory, anti -itching and vasoconstriction effects.

Dynamic pharmacy

miconazole nitrate is only absorbed very little through the skin or mucous membranes when using the skin on the skin. When used oral, the drug is absorbed completely through the digestive system.

The drug is metabolized in the liver into metabolic substances.

about 10 - 20% of oral dose is excreted in the urine in the form of metabolic.

There are about 50% of oral dose that can be excreted in the form of constant feces.

Hydrocortisone is absorbed stably through the gastrointestinal tract and reaches the peak concentration in the serum for about 1 hour. The drug is also absorbed in the skin especially when sealed and in the private area.

Hydrocortisone is metabolized in the liver and in most body tissues into tetrahydrocortisone and tetrahydrocortisol.

These substances are excreted into urine mainly in the form of glucuronid.

Before taking Axcel Fungicort Cream to treat dermatitis, skin allergies (15g)

How to use

axcel fungicort cream 15 g used on the skin.

Dosage

Apply mild pills with fingers to the lesion area depending on the size of the sick area, 1-2 times/day. Do not stop the drug until the area is completely cured.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Blood and severe diabetes.

Patients may be more susceptible to infections. The use of large doses of corticosteroids can cause typical Cushing symptoms of the adrenal gland's energy condition with a round face like the moon, sometimes hairy, camel tumor, red face, mirror, stretch marks and acne. If you stop taking the medication, the symptoms will often be lost but if you stop the drug suddenly, you may be in danger.

Overdose treatment: mainly symptomatic treatment along with slow stopping.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.

Side Effects

When using Axcel Fungicort Cream 15 G, you may experience unwanted effects (ADR).

There may be local irritation and sensitive reactions when using miconazole on the skin. Contact contact dermatitis.

The use of corticosteroid drugs may lose the collagen fibers of the skin and atrophe under the skin, there is a decrease in the subcutaneous layers in the deep parts of the skin after using corticosteroids.

Glucocorticoid causes immunosuppressive, increasing the likelihood of infection, fungal infection, virus.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Axcel Fungicort Cream 15 G contraindicated in the following cases:

Skin tuberculosis, chickenpox, herpes Simplex infection.

Too hypersensitivity to any ingredients of the drug.

Skin ulcers.

Caution when using

When using topical topical skin on a large scale, when the skin is torn or bandaged, the corticosteroids can be absorbed in sufficient amounts that cause systemic effects. Avoid prolonged use in children, children and medication in the face.

The ability to drive and operate machinery

does not affect.

Pregnancy

Safety when using miconazole and Hydrocortisone topical skin for pregnant women have not been set. Therefore, it is not advisable to apply medicine on a large and long -term time when used for pregnant women.

Breastfeeding period

Safety when using miconazole and Hydrocortisone topical skin for breastfeeding women have not been set. Therefore, it is not advisable to apply medicine on a large and long -term time when used for nursing women.

Medicinal interaction

The combination of drugs between amphotericin and miconazole seems to be poor with Candida albicans on both in vitro and in vivo compared to each separate medicine. Rifampicin reduces the activity of corticosteroids.

Storage

Store at temperatures below 250C.

Expiry date: 3 years from the date of manufacture. Do not use overdue drugs stated on the packaging.

Manufacturer: Kotra Pharma Company (M) SDN. BHD.

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