Azintal Forte medicine for flatulence, indigestion, bloating (10 blisters x 10 tablets)
Dosage form Tablet
Specifications Box of 10 blisters x 10 tablets
Ingredient Simethicone, pancreatin, azintamide, cellulase 4000
Ingredient
| Composition information | Content |
| Simethicone | 50mg |
| Pancreatin | 100mg |
| Azintamide | 75mg |
| Cellulase 4000 | 10mg |
Uses
indications
Azintal Forte is indicated in cases of symptomatic treatment related to the deficiency of bile secretion or a shortage of digestive enzyme:
Pharmacy
pancreatin originating from pigs is prepared in the form of intestinal soluble cysts (antacids). The drug quickly dissolves in the stomach to release hundreds of micro cysts, created on the principle of multi -dose to achieve a good mix with nutrients and after escaping, they evenly distribute enzymes into nutrients.
When the cysts come to the small intestine, the coat is quickly melted (at the pH> 5.5) releasing enzymes with fat, starch and hydrolyzed protein to ensure the digestion of fat, starch and protein. Products digested by the digestive enzyme of the pancreas are then directly absorbed or hydrolyzed by digestive enzymes in the intestine.
Simethicon is a substance that reduces flatulence and indigestion.
azintamide is a biliary medicine.
Mechanism of action
Simethicon is an unrelian dehydration, it changes the surface tension of the vapor balls in the digestive system. The bubbles are broken down or combined and this gas is easily removed through belching or medium.
pharmacokinetics
Animal studies do not show evidence of the absorption of intact enzymes, so the classic pharmacokinetic studies are not done. Pancreatic enzyme supplements do not need absorption to work. In contrast, their adequate treatment is created from the heart of the gastrointestinal tract. Moreover, they are proteins, so they suffer from digestion through protein hydrolysis while walking throughout the gastric tract before being absorbed in the form of peptid and amino acids.
Simethicon is a physiological inert substance, it is not absorbed through the gastrointestinal tract or hindering the secretion of stomach acid or the absorption of nutrients. After oral, the drug is eliminated in the form of unchanged in the feces.
Before taking Azintal Forte medicine for flatulence, indigestion, bloating (10 blisters x 10 tablets)
How to use
Should use Azintal Forte along with food, during or after meals.
Dosage
Azintal Forte dose in adults
1 - 2 capsules, 3 times/day.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
In very high doses, external pancreatic enzymes can increase uric acid and blood uric acid.
What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
When using Azintal Forte, you may experience unwanted effects (ADR).
Rare side effects (ADR> 1/10000 to
In very high doses, external pancreatic enzymes can increase urinary uric acid and blood uric acid.
Notice immediately to the doctor or pharmacist the harmful reactions encountered when using the drug.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Azintal Forte is contraindicated in the following cases:
Precautions when using
Do not chew or suck azintal forte.
People who are sensitive to pig proteins should avoid taking medication or caution when using.
The ability to drive and operate machinery
There is no evidence of the effect of the drug on the ability to drive and operate machinery.
Pregnancy
There has been no research on the impact of Azintal Forte's fetus on animals. There is no data on drug use in pregnant women, should only be used if the benefits are superior to the risk.
Breastfeeding period
Women in the period of breastfeeding should use azintal Forte carefully because the current unknown distribution of Azintal Forte in breast milk.
Drug interaction
Reports show that Simethicon interacts with Quinidine: Because when using Simethicon will increase the plasma concentration of quinidine. This interaction is because Simethicon alkaline urine thus increases the reabsorption of quinidine in the kidneys. Therefore, if the patient combines these two drugs, it is necessary to closely monitor the manifestations due to quinidine overdose, adjust the quinidine dose if necessary.
The reports also show that simethicon increases carbamazepin concentration when used, so it can cause carbamazepine overdose. It is necessary to strictly control overdose phenomena due to carbamazepin , adjust the dose if necessary.
There has been no research on drug interaction issues of pancreatin, azintamid, cellulose to other drugs.
Storage
In closed packaging, avoid moisture, avoid light, temperature below 30 c.
Expiry date: 36 months from the date of production.
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