B-Sol Agimexpharm skin cream for psoriasis and eczema (10g)

Dosage form Tube
Specifications Clobetasol Propionate
Ingredient Agimex

Ingredient

Composition information	Content
Clobetasol Propionate	5mg

Uses

Indications

B-SOL drugs are used in cases of reducing inflammatory manifestations of skin diseases that respond to corticosteroids, especially valuable in short-term treatment of difficult skin diseases such as:

Psoriasis (except for psoriasis psoriasis). Learning

Clobetasol Propionat is a strong synthetic corticosteroid.

The mechanism of action of topical corticosteroids is due to combination of three important properties: anti -inflammatory, anti -itching and vasoconstrictor effect.

Active ingredient Clobetasol propionate is differential in cream drugs to ensure effective contact with the skin and for quick onset.

pharmacokinetic

absorption

When used on the spot, corticosteroids on normal skin are intact, only a small amount of drugs reach the pit and then into the general circulatory system. However, the absorption increases significantly when the skin is lost Keratin, inflamed or/and other diseases in the epidermal fence (such as psoriasis, eczema).

Depending on the degree of permeability, the amount of topical and skin condition at the top of the drug, the drug is more absorbed in the scrotum, armpits, eyelids, face and scalp (about 36%) and is absorbed less at the forearm, knee, elbow, palms and soles of the feet (about 1%). Even after washing the drug, corticosteroids are still absorbed for a long time, possibly because the drug is kept in the horny layer.

Distribution

through the skin, the amount of drugs absorbed will be distributed into the skin, muscles, liver, intestines, and kidneys.

Metabolism

Corticosteroids are initially metabolized in the skin, a small amount is absorbed into the circulatory system and is metabolized in the liver into non -effective substances.

Elimination

The drug excreted through the kidneys is mainly in the form of glucuronid and sulfate, but also has an inexplicable amount. A small amount of metabolites except for feces.

Before taking B-Sol Agimexpharm skin cream for psoriasis and eczema (10g)

How to use

B-sol drugs are used on the skin.

Dosage

Apply a thin layer of drug to the skin once or twice daily. Should stop treatment immediately after the desired effect.

Do not treat continuously for more than 4 weeks without testing the patient's condition. Short-term treatments can be repeated by B-Sol to control serious problems. If you need continuous treatment with corticosteroids, you should use lighter corticosteroids.

For injury is very difficult to treat, especially in the horny skin, the anti-inflammatory effect of B-SOL can be enhanced, if deemed necessary, by covering the skin area applied to the film with polythen film. Usually just overnight bandage is enough to bring the desired response. After that, applying the drug without a tight bandage, usually the disease can continue to be improved.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical expert

What to do when overdose? However, in the case of chronic overdose or wrong use, the symptoms of adrenal shells may occur and in this case, it is necessary to immediately stop topical corticosteroids.

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using B-Sol drugs, you may experience unwanted effects (ADR).

As well as local -acting corticosteroids, when used in a large amount of prolonged, or treated on a large skin area, the drug can be absorbed in the body with sufficient amounts to cause signs of adrenal enhancement. This effect is more likely to occur in children with children and children and in the treatment of closed ice. In children with children, diapers can work as when the bandage.

With a dose not exceeding 50g per week for adults, any manifestation of the inhibition of the hill - saddle - adrenal axis is often transient and recovers quickly after stopping a short -term treatment. Prolonged treatment with high doses of strong corticosteroids can cause local atrophy such as skin cracks, thin skin, stretching surface blood vessels, especially when treating drugs with sealed bandages, or on the skin fold.

There are reports that record changes in skin pigmentation and him when using topical corticosteroids.

In rare cases, treatment (or stop treatment) psoriasis with corticosteroids is thought to have started the form of pustules of the disease.

Normally, B-sol is well tolerated, but if there are signs of hypersensitivity, should stop taking the drug immediately.

The aggravation of possible symptoms.

Stop using the drug and notify the doctor the unwanted side effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

B-sol drugs contraindicated in the following cases:

Red acne, regular acne and dermatitis around the mouth.

The form of B-Sol is not indicated for treatment of primary skin infections caused by micro-infection or fungus, skin diseases in children under 1 year of age, including dermatitis and diaper redness.

Caution when using

should avoid long-term continuous treatment with B-sol if possible, especially for children and children, because there may be adrenal inhibition, even if the area is not covered with medication.

In case of using B-sol for children, there is a fox that the treatment prescription needs to be checked weekly by the physician.

It should be noted that the diaper of the child is acting as when the skin is covered with the skin.

Facial area is more likely to shrink skin than other skin areas on the body when treated for prolonged corticosteroids, which should be memorized when treating skin diseases such as psoriasis, lupus red rash in form and severe eczema. When applying the drug on the skin around the eyes, it is necessary to be careful not to let the drug fall into the eyes, because it can cause glaucom.

Local -acting corticosteroids may be at risk of psoriasis treatment for some reasons, including recurrence, drug resistance, the risk of pustular pustular pumbles and topical or body poisoning due to damaged skin protective fence function. When using corticosteroids to treat psoriasis, careful monitoring of patients.

When infected with infection, the appropriate antibiotic treatment should be treated. When signs of infection spread, it is necessary to stop using corticosteroids in the skin and need to treat systemic antibiotics. When the skin is applied to the skin, the skin becomes warm and moisturized, it will facilitate the growth of the infection, so it is necessary to wash the skin before applying the medicine and place the tape clean up.

The ability to drive and operate machinery

does not affect.

Pregnancy

Due to the safety of topical corticosteroids used for pregnant women who have not been determined, the drug of this group should only be used when pregnant if the therapeutic benefit is higher than the risk that can be caused to the fetus.

Drugs of this group should not be over -use at a large dose or for a long time for pregnant women.

Breastfeeding period

is currently unaware of whether the amount of topical corticosteroids is absorbed into the blood so that it can be found in breast milk or not.

The body corticosteroids are used through breast milk with a very small amount that is not likely to cause adverse effects on children. However, when deciding to continue treating or stopping the drug should pay attention to the importance of the drug with the mother.

Drug interaction

only occurs when long -term use or widespread use of the skin with absorption and body effect.

To avoid drug interactions, notify the doctor or pharmacist about the drugs being used.

Storage

Leave a cool dry place, avoid light, temperature below 30 ° C.

To be out of reach of children.

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