Bart 20mg Sosepharm medicine for rheumatoid arthritis, osteoarthritis (3 blisters x 10 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Tenoxicam
Ingredient Edema after injury, neuritis, gout, osteoarthritis, back pain, epidemic inflammation, joint spondylitis, tendonitis, arthritis, rheumatoid arthritis, bone inflammation

Ingredient

Composition information	Content
Tenoxicam	20mg

Uses

Indications

Bart drugs are indicated in the following cases: Tenoxicam is indicated as an anti -inflammatory analgesic drug in the treatment of rheumatoid arthritis, osteoarthritis, vertebral inflammation, gout and external rheumatoid disorders (tendonitis, epidemic inflammation, neuritis, back pain) and post -traumatic swelling.

Pharmacokology

Pharmacological group: nonsteroidal anti -inflammatory drugs, Oxicam conductive groups.

Tenoxicam is an nonsteroidal anti -inflammatory drug that has a significant anti -inflammatory and analgesic effect and somewhat cooling effect. Like other nonsteroidal anti -inflammatory drugs, currently it is unknown to exactly the effect of Tenoxicam's effect, although there are many assumptions that prostaglandin biosynthesis inhibit bloody biosynthesis, reducing leukemia in the inflammation.

Tenoxicam is used to treat bone - joints and rheumatoid degeneration symptoms and even short -term management of soft tissue lesions. Tenoxicam does not affect the progression of some rheumatoid arthritis forms.

Like other nonsteroidal anti -inflammatory drugs, Tenoxicam causes damage to the gastrointestinal tract due to the decrease in prostaglandin, which leads to inhibition of mucin formation (substances that protect the gastrointestinal tract). Prostaglandin plays a role in maintaining kidney perfusion.

nonsteroidal anti -inflammatory drugs inhibit prostaglandin, so it can cause interstitial nephritis, glomerulonephritis, kidney necrosis and nephrotic syndrome especially in people with kidney disease or chronic heart failure. For these patients, nonsteroidal anti -inflammatory drugs can increase acute renal failure and acute heart failure.

pharmacokinetic

absorption

After using about 1 to 2.6 hours when hungry and 4-6 hours when No, Tenoxicam reaches the maximum concentration. Food slows down the absorption process but does not reduce the bioavailability of the drug.

Distribution

highly linked with protein and absorb a significant amount into the synovial membrane. Half life eliminates about 70 hours. If daily use, stability is achieved within 10-15 days.

Metabolism

Tenoxicam is completely transformed into a non -active form.

Elimination

Tenoxicam metabolites are eliminated through urine and feces.

Before taking Bart 20mg Sosepharm medicine for rheumatoid arthritis, osteoarthritis (3 blisters x 10 tablets)

How to use

Take oral use, can drink when hungry or full.

Dosage

Adults

The usual dose is 20mg (1 capsule), once a day.

In the exacerbation of gout arthritis, the recommended dose is 40mg once a day for 2 days after 20mg/day for 5 days.

Children

Not for patients under 15 years old.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Use measures to reduce the absorption and increase the rate of elimination of drugs: for gastrointestinal lavage as soon as possible after overdose and closely monitor patients, support treatment if necessary:

may cause vomiting to eliminate drugs but should not use ipeca syrup because it can cause symptoms similar to nonsteroidal anti -inflammatory poisoning, causing further complicated diagnosis.

can be used for activated carbon, but the effect of activated carbon reduces the absorption of nonsteroidal anti -inflammatory drugs that have not been clearly defined if given after two hours.

Symptoms of poisoning on digestive, can be treated by patients using antacids and H2 receptor inhibitors.

If you need to remove Tenoxicam from the digestive system, use 3 doses of 4g cholestyramin.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Bart may experience side effects:

Common, ADR> 1/100

Body: headache, dizziness.

digestive: epigastric pain, nausea, indigestion.

Skin: Outdoor, urticaria, itching.

Uncommon, 1/1000

Body: Fatigue, edema, anorexia, dry mouth.

Circulation: Brushing the chest.

Gastrointestinal: vomiting, persistent constipation, diarrhea, stomatitis, gastrointestinal bleeding, duodenal and stomach ulcers, gastritis, black bowel movements.

Mental: Sleep disorder.

urinary - genital: edema.

Rare, ADR

Body: Hypersensitivity reaction (asthma, anaphylactic, angioedema).

Blood: Anemia, leukemia, granulocytosis, thrombocytopenia, bleeding due to platelets inhibitors.

Circulation: Hypertension.

Neurological: blurred vision.

Skin: Sensitive to light, Stevens - Johnson syndrome, poisoning epidermis (lyell syndrome).

urinary - genital: difficulty urinating.

Warnings

Contraindicated

History of sensitivity to Tenoxicam, with any ingredients of the drug.

Patients with a history of gastrointestinal bleeding, peptic ulcer, indigestion.

Patients with cardiovascular disease: heart failure, severe hypertension.

Other cases: severe blood disorders, organs, severe hepatitis, renal disease, patients with surgery/anesthesia.

Do not use Tenoxicam in the case of patients who are taking aspirin or other NSAIDs, pregnant women.

Precautions when taking drugs

Patients with a history of gastrointestinal disease.

Patients with risk of renal failure (elderly people, people with a history of kidney disease, diabetes, cirrhosis, hemorrhagic heart failure, reduced blood volume, treated simultaneously with diuretics or drugs that can be toxic to the kidneys) should be controlled by kidney and cardiovascular function.

Patients who had a rash reaction (Stevens-Johnson syndrome, epidermal necrosis) when using Bart.

Be cautious with patients with large surgery (such as joint replacement) because Tenoxicam reduces platelet condensation, so it can extend the bleeding time.

The ability to drive and operate machinery

Do not use medication for people while driving or operating machinery.

Pregnancy

Tenoxicam causes prostaglandin synthesis inhibitors that adversely affect the pregnancy or embryo development. Therefore, do not use drugs for pregnant women.

Breastfeeding period

Do not take the drug. If used is necessary, consult your doctor to consider benefits and risks.

Medicinal interaction

To avoid drug interaction, it is best to write a list of drugs that are used (including prescription, non -prescription, herbal, functional foods) and to the doctor or pharmacist.

To ensure safety when taking the drug, you do not arbitrarily take the drug, stop or change the dosage of the drug without the doctor's permission.

Avoid using Tenoxicam with:

Corticosteroid drugs: Increases the risk of ulcerative or stomach bleeding. dehydration), simultaneous absorption along with enzyme inhibitors, Angiotensin II and cyclo-oxygenase inhibitors can cause further impairment of kidney function. High amount of lithium on a toxic threshold. Tenoxicam. Other NSAIDs, Tenoxicam reduces the hypotension of the alpha-adrenergic blockers and enzyme inhibitors, simultaneously used Tenoxicam and Digoxin, causing serious side effects.

Storage

You should store at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer. You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist. Keep pills out of reach of children and pets.

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