Becolitor 20mg Meyer-BPC Treatment for total cholesterol treatment, LDL-Cholesterol (30 tablets)

Dosage form Box of 3 blisters x 10 tablets
Specifications Atorvastatin
Ingredient Meyer-BPC Joint Venture Company

Ingredient

Composition information	Content
Atorvastatin	20mg

Uses

Indications

beColitor 20 is indicated in the following cases:

is indicated as a drug that supports diet in the treatment of patients with total cholesterol hypertrophy, LDL-Cholesterol, Apolipoprotein B and Triglycerides and to increase HDL-cholesterol in patients with primary blood cholesterol (hyperlymer blood cholesterol with heterozygous and non-family family, hyperlemia Blood and in patients with blood betalipoprotein disorders without adequate response to the diet.

Reduces total cholesterol and LDL-cholesterol in patients with hyperlested blood cholesterol with homosexuality when diet and other non-medication methods do not respond. methylglutaryl-coenzyme A (HMG-CoA Reductase). This enzyme catalyzes the HMG-CoAa to Mevalonate in the process of synthesizing cholesterol.

pharmacokinetic

absorption

Atorvastatin is quickly absorbed after taken, the drug concentration, in the maximum plasma is achieved within 1-2 hours. The level of absorption and concentration of Atorvastatin increases proportional to the dosage of Atorvastatin.

Distribution

Over 98% Atorvaslatin is bound to plasma proteins.

Metabolism

Atorvastatin is converted mainly into hydroxylation derivatives at Ortho and Para positions and oxidized products at Beta.

Elimination

Atorvastatin and its metabolism are excreted mainly through bile after the metabolism in the liver or outside the liver.

Before taking Becolitor 20mg Meyer-BPC Treatment for total cholesterol treatment, LDL-Cholesterol (30 tablets)

How to use

oral medication.

Dosage

Hyper cholesterol (heterozygous and non -family family) and mixed blood lipid disorders:

The starting dose is 10mg or 20mg once a day. If you need to reduce LDLCHOLesterol, you can start at a dose of 40mg once a day.

Atorvastatin treatment dose is 10 - 80mg once a day.

Hyper cholesterol hyperlested family nature: Dosage 10 - 80mg daily treatment. Need to coordinate other lipid measures (LDL filtration measures).

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Bocolitor 20, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Digestive: constipation, flatulence, indigestion, abdominal pain, nausea, diarrhea.

Neurological: headache, dizziness, blurred vision, fatigue, insomnia, cognitive impairment.

muscle joints: muscle pain, joint pain, muscle weakness.

Uncommon, 1/1000

muscle disease (combining muscle weakness and increased content of creatine phosphokinase plasma (CPK), skin rash, rhinitis, sinusitis, sore throat, cough.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

BECOCOT 20 contraindicated drug in the following cases:

Patients sensitive to any ingredient of the drug.

People with liver disease are progressing or increased serum transaminase exceeding 3 times the upper limit of normal levels.

Pregnant or breastfeeding women.

Precautions when using

The effect of the drug on the liver

Moderate increase (> 3 times the upper limit of the normal level) of serum transaminase has been recorded after treatment with Atorvastatin. The liver enzyme tests should be performed before starting treatment and periodic. Patients with any functional symptoms or entities that suggest liver damage should be tested for liver function.

If Alt or AST increases to 3 times the upper limit of the persistent normal level, the dose should be reduced or stop using Atorvastatin.

Use cautiously in patients with alcohol or a history of liver pathology.

Effects of skeletal muscles

Consider monitoring Creatin Kinase (CK) in the case: Before treatment, CK tests should be conducted in the following cases: impaired renal function, hypothyroidism, self -history or family history of genetics, a history of disease D due to statin or Ibrate before, a history of liver disease or drinking alcohol, elderly patients (> 70 years old) Number of special patients.

In these cases, the benefits/risks should be considered and monitor patients clinically when treated with statin. If the results of CK test> 5 times the upper limit of normal levels, do not start treatment with statin.

During statin treatment, patients need to notify when there are muscle manifestations such as muscle pain, muscle stiffness, muscle weakness. When there are these manifestations, patients need to test CK to take appropriate interventions.

The ability to drive and operate machinery

Precautions when used for people who are driving or operating machinery because the drug can cause headaches, fatigue and cognitive impairment.

Pregnancy

Do not take medicine for pregnant women.

Breastfeeding period

Do not take medicine for breastfeeding women.

Medicinal interaction

Simultaneously used with oral Antacid epidemic containing magnesium aluminum hydroxyd, which will reduce the level of Atorvastatin in plasma.

Concentrated with digoxin will increase plasma digoxin levels.

Concentrated with erythromycin will increase plasma Atorvastatin levels.

Be cautious when using Atorvastatin with oral contraceptives containing, norethindrone, ethinyl estradiol will increase the effects of these drugs.

Increased risk of muscle lesions when used simultaneously with the following drugs: Gemfibrozil, other fibrat blood cholesterol medications, high doses of niacin (> 1g/day), Colche Cyclosporin, antifungal group Azole.

may increase the risk of muscle damage, the most serious is muscle pattern, kidney damage leads to renal failure and can be fatal when used simultaneously with protease inhibitors to treat HIV and hepatitis C (HCV).

Storage

Leave a cool dry place, avoid light, temperature below 30⁰C.

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