Berlthyrox 100 Menarini medicine treatment thyroid disabilities (4 blisters x 25 tablets)

Dosage form Box of 4 blisters x 25 tablets
Specifications Levothyroxine
Ingredient Goiter, hypothyroidism, hyperthyroidism

Ingredient

Composition information	Content
Levothyroxine	100mcg

Uses

Indications

Berlthyrox 100 drugs are indicated in the following cases:

Used to replace treatment for armor hormones (thyroid disabilities).

Prevent the hypertrophy of the thyroid gland after cutting the tumor in cases of normal thyroid function. armor.

Code ATC: H03AO01.

Berlthyrox contains synthetic levothyroxine that is similar to the natural thyroid hormone synthesized mainly from the thyroid. After converting partially into Liothyronine (T3) in the liver and kidneys, the drug enters the cells in the body, the specific effects of the thyroid hormones are observed instead of the development, growth and metabolism of the body.

pharmacokinetics

When taking the drug when hungry, levothyroxine is absorbed up to 80%, mainly in the small intestine. The peak concentration in plasma is about 6 hours after taking the drug. At the beginning of the treatment, the onset effect is usually seen after 3-5 days. The drug distribution is about 1/2L/kg. Over 99% levothyroxine in the body in the form of plasma proteins. The metabolic clearance coefficient is about 1.2L plasma/day, the drug is mainly metabolized in the liver, kidney, brain and muscle. Due to the high ratio of plasma proteins, thyroid hormones only appear in small quantities when hemolysis.

Before taking Berlthyrox 100 Menarini medicine treatment thyroid disabilities (4 blisters x 25 tablets)

How to use

daily dose is taken by swallowing all pills with a small amount of water in the morning, when the stomach is empty, at least 1/2 hours before breakfast.

Children take the medicine at least 1/2 hours before the first meal of the day. Put the pills with a little water for the drug to dissolve and become a smooth mixture (should only be done for each drink), then let the child drink with a little more water.

Time to use Berlthyrox 100:

Hypothyroidism: Usually used for life. If the Berlthyrox treatment does not bring the desired results during this period, it is possible to consider other treatments. Drugs.

Dosage

always comply with the exact dose of the doctor prescribed. Ask your doctor or pharmacist if you are not sure.

Daily dose for each individual should be calculated based on clinical and subclinical tests. The beginning of the thyroid hormone treatment must be especially cautious in elderly patients, in patients with coronary artery disease and patients with severe or prolonged thyroid diseases, for example: low starting dose and then increasing the dose slowly, regularly checking the hormone concentration after each dose increasing.

Experience shows that low doses have a good effect on mild people and cases of patients with large kernel goiter.

Indications

Dose (McG/Day) 100 - 200

Armor 50 - 100 armor) In long -term cases of treatment, the dose depends on many factors such as age and weight of children.

Dosage guidance in children:

Age dose
(mcg/day) dose
(mcg/kg/day) 6 months 25 - 50 10 - 15 Age 100 - 200 3 - 4 Good to help the normal development of children's mental mental mental illness. Levothyroxine concentration should be adjusted in the high level of the normal value of the normal value in the first 3-4 years. In the first 6 months of life, the blood -levothyroxine test in the blood is more significant than the TSH level (hormone stimulates thyroid).

In some cases, the process of normalizing TSH levels may take up to 2 years despite providing adequate levothyroxine. If possible, use the dosage form with a low active ingredient when it is started to treat and when increasing the dose for both adults and children.

When long -term treatment, switch to high active ingredients.

Attention when breaking the pill: Place the pill on a smooth and hard plane, so that the surface has a groove below, and press down with a finger to divide the pill into two parts.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Please see a doctor if the above symptoms occur.

What to do when forgetting a dose?

If you stop using Berlthyrox 100

Using Berlthyrox 100 regularly with a prescribed dosage makes the treatment successful. If the treatment is interrupted or stopped early treatment, the symptoms of the old disease may be recurred.

If you have any other questions about this medication, ask your doctor or pharmacist.

Side Effects

Like other drugs, Berlthyrox 100 can cause unwanted side effects, although not all encounter.

The following frequency is used as a basis for assessing the frequency of unwanted side effects.

Very popular (≥ 1/10) when appearing> 1 of every 10 people use the drug.

After consulting the doctor, should reduce daily dose or stop the drug for a few days. Immediately after all these side effects, the drug can be reused but cautious about the dose.

In case of hypersensitivity to levothyroxine or any excipients, allergic reactions may occur including: urticaria, bronchospasm that leads to shortness of breath and laryngeal edema. Very rare reports of anaphylaxis. Come to the doctor immediately if there is a hypersensitivity reaction.

If any unwanted side effects become serious, or if your teacher appears any unwanted side effects that have not been listed in the prescription information sheet, notify your doctor or pharmacist.

Warnings

Before using Berlthyrox, you need to read the instructions carefully and refer to the information below.

Contraindicated

Berlthyrox drugs are contraindicated in the following cases:

Hypersensitivity to active ingredients or any excipients of the drug.

Caution when using

Before starting treatment with Berlthyrox 100, should eliminate or treat the following diseases: coronary artery disease (e.

Avoid taking the drug in cases of coronary artery disease, heart failure, tachycardia and or hyperthyroidism despite mild disease.

In the case of hypothyroidism due to the pituitary insertion, whether it must be accompanied by adrenal insufficiency. If so, first of all must treat adrenal insufficiency before starting treatment with thyroid hormones.

Levothyroxine treatment for menopasal women with high risk of osteoporosis, should check the thyroid function regularly to avoid high blood Levothyroxine levels.

If you are being treated with a selamer due to high blood phosphate concentration, you are hemolysis, the doctor may consider checking some of your blood parameters to consider the effect of levothyroxine.

Be careful and regularly check in elderly patients.

The ability to drive and operate machinery

There is no special caution.

Pregnancy and nursing mothers

consult a doctor or pharmacist before taking any medication.

During pregnancy and breastfeeding should be treated for additional thyroid hormones. So far, no risk has been detected for fetuses even when taking large amounts of drugs for pregnant women. The amount of thyroid hormone excreted in breast milk is very small, even when high doses of high doses Levothyroxine, and therefore, does not harm breastfeeding.

The need to use levothyroxine in pregnant women with hyperthyroidism is due to increased oestrogen hormone levels (female sex hormones). Therefore, it is necessary to check the thyroid function during and after pregnancy and adjust the dose appropriately.

However, Berlthyrox 100 is not used with anti -thyroid drugs during pregnancy because it is necessary to take higher anti -thyroid dose. Because anti -thyroid drugs, unlike levothyroxine, can be through the placenta fence at the usual doses, this can cause hypothyroidism to the fetus. For this reason, always use low -dose anti -thyroid medications for pregnant women with hyperthyroidism. Do not do thyroid inhibiting tests during pregnancy.

When pregnant and breastfeeding, the exact dose must be obeyed and not overdosed.

Medicinal interaction

Please notify your doctor or pharmacist if you are taking any drug recently, including non -prescribing drugs.

Increasing the effectiveness of Berlthyrox 100 leads to an increased risk of unwanted effects when used with the following drugs:

Salicylates (painkillers, fever), Dicoumarol (anticoagulant drugs), high -dose Furosemide (diuretics) (250mg), clofibrate (blood -lowering drugs) and other drugs may increase the concentration of levothyroxine in the blood. heart.

Reduce the effectiveness of Berlthyrox 100 when combined with the following drugs:

Colestyramine and Colestipol (medications of lipid liposuction) inhibit the absorption of levothyroxine, so they should not use these drugs within 4-5 hours after taking Berlthyrox 100.

The absorption of levothyroxine may be reduced when used with aluminum -containing drugs, stomach acid resistance, calcium carbonate or iron -containing drugs. Therefore, Berlthyrox should be used at least 2 hours before these drugs. Chloroquine/Proguanil (Treatment of malaria and rheumatism) reduces the effectiveness of levothyroxine. Kinh. Therefore, it is advisable to use Berlthyrox 100 before using 1 hour SEVEVEA or after 3 -hour SEVELAMER. The doctor must check the thyroid hormone concentration regularly (see more caution).

Other interactions:

Amiodarone (medication for arrhythmia) can cause hyperthyroidism or hypothyroidism due to high iodine concentration in the drug. Therefore, it is necessary to be particularly cautious when used for patients with thyroid thyroid. Therefore, if treating these drugs with levothyroxine must check blood clots and blood glucose concentrations regularly, especially when starting treatment and should adjust the dose of these anticoagulants and hypoglycemic drugs.

Use Berlthyrox 100 with food and drink:

Soy products can reduce the absorption of Berlthyrox 100 in the intestine. The adjustment of the Berlthyrox 100 dose may be necessary when starting and after stopping the diet -containing diet.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

Do not cancel the drug by wastewater and domestic waste. Ask the pharmacist about how to cancel the drug no longer need to use. This helps to protect the environment.

To be out of reach of children.

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