Betadine Throat Spray Spray for acute oral mucosal infections (50ml)

Dosage form Spray solution
Specifications Bottle x 50ml
Ingredient Povidone-iodine

Ingredient

Composition informationContent
Povidone-iodine0.45

Uses

Indications

Spraying betadine drugs are indicated in the following cases:

  • Treatment of acute oral and throat mucosa including stomatitis, gingivitis, aphid, sore throat, tonsillitis, Candida fungal infection, common cold and flu. Learning

    Povidon-iodine is a complex of polyvinylpyrrolidone polymer polymer with iodine (Povidon-Id) that after use, continue to release iodine for a period of time. Elemental iodine (I2) has long been known as a microorganism that is highly effective and quickly destroys bacteria, viruses, fungi and some in vitro mononeries.

    Two relevant mechanisms are: Free iodine quickly destroys microorganisms, while iodine is associated with polymers acting as a source of reserves. Because the drug is exposed to the skin and the mucosa, more and more iodine is separated from the polymer. Free iodine reacts with -h or -OH groups that can be oxidized by amino acids in enzymes and structural proteins of microorganisms and therefore inactivated and destroy these enzymes and proteins. Most vegetable microorganisms are destroyed in less than a minute in vitro, with most destroyed within 15 to 30 seconds. In this process, iodine is discolored; Therefore, the darkness of brown is considered as its indicator of its effectiveness. May need to be used again when discolored. There is no report on drug resistance.

    pharmacokinetic

    absorption

    In normal people, iodine is absorbed very little into the blood when used on the spot. This product is used on the spot for the mouth and throat.

    Povidon (PVP):

    absorption and especially, excreting through the kidney of Povidon depends on the molecular weight (average) of the mixture. With a molecular weight greater than 35000 to 50000, it must be expected to reserve drugs.

    iodine:

    pharmacokinetics of iodine or iodid after being absorbed in organisms are largely similar to iodine absorbed by other lines. The distribution volume corresponds to about 38% of the body weight in kilograms.

    Eliminate almost entirely by kidney with clearance of 15 to 60 ml of plasma/minute depending on the serum iodine concentration and creatinine clearance.

    • Before taking Betadine Throat Spray Spray for acute oral mucosal infections (50ml)

    How to use

    Line used: on the spot (mouth and throat).

    Dosage

    Spray into the throat mucosa several times a day (every 3-4 hours).

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    Symptomatic treatment and support

    In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

    What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not use double the prescribed dose.

    Side Effects

    When using a Betadine spray, you may experience unwanted effects (ADR).

    Betadine Throat Spray throat spray can cause irritation in the mouth as well as hypersensitivity reactions. Stop the drug in case of local irritation due to sensitivity.

    Notify the doctor with unwanted effects when using the drug.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Betadine throat spray is contraindicated in the following cases:

    In case of being or suspected hypersensitivity to iodine or Povidon or any other excipient has been listed in the part of the preparation characteristics.

    In case of increased thyroid (hyperthyroidism), other manifestations of thyroid diseases, as well as before and after the treatment of radioactive iodine, until the disease has recovered for a long time. Do not use the drug within 4 weeks before radioactive iodine radiation or treatment of thyroid carcinoma with radioactive iodine. Patients with goiter, thyroid nucleus, or other thyroid diseases (especially elderly patients) are at risk of increased thyroid energy (hyperthyroidism) due to using a large amount of iodine.

    Not used on patients treated simultaneously lithium.

    Not used for children under 6 years old.

    Precautions when using

    Need to be especially cautious when used regularly on damaged skin in patients with renal failure.

    Only in the mouth and throat. Do not apply to the skin.

    Stop use in case of on -site irritation or sensitivity.

    To be out of reach of children.

    The ability to drive and operate machinery

    unknown.

    Pregnancy

    During pregnancy, only use the pharyngeal betadine if the doctor prescribes and the use of the drug is only at a minimum, because the absorbed iodine can overcome the placenta fence.

    Using Povidon-Id can cause transient hypothyroidism on the fetus. Povidon-iodine should be avoided in these cases.

    Breastfeeding period

    During breastfeeding, only use Betadine Spray if the doctor prescribes and the use of the drug is only at a minimum, because iodine is absorbed can be excreted into breast milk.

    Using Povidon-Id can cause transient hypothyroidism on infants. Povidon-iodine should be avoided in these cases. In these cases, it is necessary to check the child's thyroid function, especially in localities known to have a low amount of iodine in a diet and tend to have goiter. In addition, must avoid the fact that children can swallow Betadine Throat Spray.

    Drug interaction

    Effective Povidon-IUD complex at pH values ​​from 2.0 to 7.0. The complex is considered to react with protein and other unsaturated organic compounds, leading to reducing the effectiveness of the drug.

    Concomitant use with products containing enzymes, hydrogen peroxide, silver and taurolidine leads to reduced effectiveness of both substances.

    Concentrated use with mercury -containing products can lead to a substance that can be harmful to the skin.

    This medication can affect thyroid tests or functions and can lead to a discontinuation of an expected thyroid treatment with iodine. Only a new radiotherapy test should only be done after the end of treatment for at least 1-2 weeks.

    When infected with Povidon - iodine, some tests to detect blood in the stool or blood in the urine can produce fake positive results.

    Storage

    Storage below 30 ° C.

    To be out of reach of children.

    Expiry date: 36 months from the date of manufacture. Do not use overdue drugs stated on the packaging.

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