Betadine vaginal disinfectant to treat vaginal infections (125ml)

Dosage form Vaginal disinfectant solution
Specifications Bottle x 125ml
Ingredient Povidone iodine

Ingredient

Composition information	Content
Povidone iodine	10%

Uses

Indications

Betadine vaginal disinfectant gynecological is a vaginal wash agent in the treatment of vaginitis caused by Candida, Trichomonas, Non -specific infections or mixture, and to clean the vagina before surgery.

Dược lực học

Povidone - iodine là một hỗn hợp trùng hợp polyvinylpyrrolidone với iodine (povidone - iodine) mà sau khi sử dụng sẽ tiếp tục giải phóng ra iod. The iodine element (I2) has long been known as a highly effective antiseptic such as quickly killing bacteria, viruses, fungi and some virus animals in vitro. Two active mechanisms include: free iodine to kill germs and while iodine binding in polymerization is the source of reserves. When the drug is exposed to the skin and mucous membranes, the iodine is separated from the polymer. Free iodine reacts with groups - SH or - OH can be oxidized by amino acids in enzymes and protein structure of microorganisms, thus being inactivated and destroying those enzymes and proteins. Most microorganisms in the process of vegetative are destroyed in just less than a minute in vitro with a lot of destruction in just 15 to 30 seconds. In this process, iodine is discolored; Accordingly, it can be seen that the level of effect of the drug through the darkness of brown. The reminders may be recommended when discoloration. Drug resistance has not been reported.

pharmacokinetic

absorption: Normally, using iodine on the spot leads to body absorption of a very small amount. However, when used in iodine vagina is quickly absorbed and plasma concentrations of all inorganic iodine and iodine increases significantly.

Povidone (PVP): The absorption and especially excretion through Povidone's urinary tract depends mainly on molecular weight (of compound). With the weight from greater than 35000 to 50000 can cause urinary retention.

iodine: How to absorb iodine or iodine compounds into organizations similar to when iodine is used by other lines. Selling time after use in the vagina is about 2 days. Elimination mainly by urinary tract.

Before taking Betadine vaginal disinfectant to treat vaginal infections (125ml)

How to use

Use gynecological betadine to wash vagina daily, best in the morning.

Dosage

Use gynecological betadine once a day, within 14 days (including menstrual days) or as directed by the doctor:

Pour 2 tablespoons of solid solution into the bottle. Push as much as possible as possible by gently pressing the squeezed bottle to allow the solution to flow naturally from the vagina. End. Dry the vaginal area with a cloth or clean paper towel. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose?

Symptomatic and support treatment.

What to do when forgetting a dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

Side Effects

When using Betadine to wash gynecological, you may experience unwanted effects (ADR).

Rarely occurs skin sensitivity reactions (different sensitivity) (for example, allergic reactions - prolonged contact (tube sensitivity reaction IV), which may appear in the form of itching (no other typical), erythema, small blisters or similar manifestations.

Very rarely occur acute systemic allergic reactions (hypersensitivity reactions) to the type of hypotension (reducing blood pressure) and/or shortness of breath as well as cases of acute mucosal and acute skin (angioedema) have been reported.

Long -term treatment of Povidone - iodine solution in the treatment of wounds and burns on a wide -scale skin can lead to clear iodine absorption. In some special cases, patients with a history of thyroid disease can progress to increase thyroid function (caused by iodine), occasionally appear symptoms such as fast or continuous vessels.

After absorbing a large amount of Povidone - iodine (for example, in the treatment of burns), there is an increase in electrolyte imbalance and abnormal blood osmol levels (no other typical, increase or decrease), kidney function (other typical renal failure) with acute renal failure and metabolic acid infections mentioned until using products with iodine.

When experiencing side effects of gynecological Betadine drugs, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using Betadine to wash gynecological, you need to read the instructions carefully and refer to the information below.

Contraindicated

Betadine vaginal douche 125 ml drugs in the following cases:

Do not take the drug when it is known to be sensitive (not other typical) with iodine or povidone.

Do not take drugs when there is an excessive activity of the thyroid gland (increased thyroid function), other obvious diseases of the thyroid gland (other typical thyroid disorders), as well as before and after radioactive iodine therapy. armor.

Precautions when using

only use gynecological betadine on the spot. The process of waiting for a wet solution until dry can cause skin irritation or rarely have serious skin reactions. In the case of skin irritation or contact dermatitis or other non -different sensitivity, stop using the drug. Do not heat the drug before applying.

Patients with goiter, thyroid tumor, or other thyroid diseases (other typical thyroid disorders) are at risk of developing thyroid hyperplasia when taking iodine high doses. For this patient's subject, the Povidone - iodine solution is not used in a long period and applied on a wide skin unless indicated tightly. Even until the end of treatment, it is still necessary to observe the early symptoms of the hyperthyroidism and if it is necessary to strictly control the thyroid function.

Babies and young children are at high risk of developing thyroid energy when using high doses of IOD. Absolutely avoid any possibility of children swallowing Povidone - iodine into the abdomen.

Pregnancy and nursing mothers

During pregnancy and lactation, using only Povidone - IOD solutions when there is a strict indication and use with a minimum dosage.

Because iodine is likely to be infiltrated into the placenta and can be secreted into breast milk, and due to the increased iodine sensitivity to the fetus and babies, povidone - iodine should not be taken during pregnancy and breastfeeding. Moreover, iodine is concentrated in breast milk, similar to serum. Povidone - iodine can cause transient thyroid disabilities with increased TSH (hormonal stimulating thyroid) in the fetus or babies. It may be necessary to check the thyroid function in young children. Absolutely avoid any possibility of children swallowing Povidone - iodine into the abdomen.

Medicinal interaction

PVP - IOD complex works with pH from 2.0 to 7.0. It is likely that this complex will react to proteins and other unsaturated organic compounds, resulting in a decrease in the effect of a complex (inefficient drug).

Concentrated use with wound treatment preparations containing enzymes leads to reducing the effect of both of these substances (inhibiting drug interaction). Products containing mercury, silver, hydrogen peroxide, and taurolidine can interact with Povidone - Iod (other non -typical drug interactions) and should not be used simultaneously.

When using simultaneously povidone - iodine products or use immediately after applying octenidine contains aseptic substance right at or near the topical position can lead to loss of skin pigmentation at the top area.

Note: Due to the oxidation effect of the vaginal disinfectant solution, different diagnostic devices can produce false positive results in the laboratory (for example, tests with Toluidine or Gum Guaiac in the identification of hemoglobin or glucose in the part or urine).

The absorption of iodine from Povidone - iodine solution can hinder thyroid function tests. While using vaginal disinfectant, the iodine absorption of the thyroid gland may be reduced; This may affect various tests (flashing thyroid map, determining PBI [protein limits associated with Iod], iodine radioactive diagnosis) and may launch a thyroid treatment plan with iodine (radioactive therapy iodine). After the end of the treatment, the appropriate distance should be followed before the flashing.

Storage

Leave a cool place, avoid light, temperature below 25⁰C.

To be out of reach of children.

Expiry date: 3 years from the date of manufacture. Do not use overdue drugs in the label.

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