Betasalic Medipharco ointment for dermatitis (10g)

Dosage form Box x 10g
Specifications Betamethasone dipropionate, salicylic acid
Ingredient Medipharco Pharmaceutical Joint Stock Company

Ingredient

Thành phần cho 15g

Composition information	Content
Betamethasone dipropionate	9.6mg
Salicylic acid	450mg

Uses

indications

Betasalic drugs are indicated in the following cases:

Reduce inflammatory manifestations in the treatment of horny cell proliferation and dry skin diseases that respond to corticosteroids.

Pharmacology

betamethasone dipropionate

betamethasone is a synthetic corticosteroid, which has a very strong glucocorticoid effect, accompanied by negligible mineralocorticoid effects. 0.75 mg of betamethasone has an anti -inflammatory effect equivalent to about 5 mg of prednisolone. Betamethasone has anti -inflammatory, anti -itching and vasoconstriction effects.

Oral, injected, injected, inhaled, inhaled or applied drugs to treat many diseases that need to be indicated to use corticosteroids, except for adrenal insufficiency states, which prefer hydrocortisone with fludrocortisone supplements. Due to less mineralocorticoid effect, Betamethasone is very suitable in cases where the pathology that holds water is disadvantage. High doses, betamethasone has immunosuppressive effects.

Salicylic acid

Salicylic acid used on the spot has a strong peeling effect on the horny skin, in addition to mild antiseptic properties. The drug softens and destroys the horny layer by endogenous hydration, which can be caused by reducing pH, causing the epithelial layer to swell, then peel off. The drug has a weak antifungal effect, thanks to the peeling of the horny layer to prevent fungal growth and help antifungal drugs absorb into the skin.

pharmacokinetics

betamethasone is easy to absorb when used on the spot. When applied, especially if the skin is closed or when the skin is torn or when the rectal indentation, there may be a amount of betamethasone that is absorbed enough, causing the whole body.

betamethasone quickly distributed into all tissues in the body. The drug through the placenta and can be exported to breast milk in small amounts. Betamethasone is widely linked to plasma proteins, mainly with globulin, while albumin is less. Betamethasone is less widely linked to protein than hydrocortisone. Their selling time also tends to be longer; Betamethasone is a prolonged glucocorticoid. The fire transferred mainly in the liver, but also in the kidneys and the issue into the urine.

Salicylic acid is easily absorbed through the skin and slowly excreted through the urine.

Before taking Betasalic Medipharco ointment for dermatitis (10g)

How to use

topical skin.

Dosage

Adults: Apply a thin layer of drug to the sick area 1 to 2 times daily.

For a few patients, the maintenance dose may be applied with less drugs.

Betasalic ointment is recommended for only two weeks of treatment prescription and then the treatment will be reviewed. The maximum dose is not exceeded 60 g.

Children: Time to use in children should be limited to 5 days.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? It is necessary to keep this user manual, the box or tube sample used if possible.

Treatment: Use appropriate symptomatic treatments. Symptoms of acute adrenal secretion often recover, adjust electrolyte imbalance if necessary.

With skin -based topical preparations containing excessive prolonged salicylic acid can lead to Salicylate toxic symptoms (salicylism). The treatment of salicylic acid poisoning is symptomatic treatment. The measures should be applied so that the salicylate remove quickly from the body. Take sodium bicarbonate to alkalize urine and diuretic.

What to do when forgetting a dose? The drug should be applied again as soon as possible and in accordance with the recommended dosage.

Side Effects

When using Betasalic medicine, you may experience unwanted effects (ADR).

Common, ADR> 1/100

Light skin irritation, burning sensation.

Uncommon, 1/1000

Dry skin, irritation, itching, folliculitis, hair, skin atrophy, skin pattern, chapped, inflammation around the mouth, peeling, burning sensation, rash form folliculitis, dermatitis.

Rare, ADR

ulcerative or skin corrosion.

Systemic effects: Disorders of water and electrolytes, skeletal, digestive, nervous, endocrine, eye, metabolism and mental.

Instructions on how to handle ADR

Notify the doctor with unwanted effects when using the drug.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Betasalic drugs contraindicated in the following cases:

Red acne, acne, dermatitis around the mouth, itching around the anus and genitals.

Patients with a history of hypersensitivity to any ingredients of the drug.

Infections and viral infections, systemic fungal infections are not controlled by appropriate chemotherapy.

Not used on wide skin, chapped skin, sensitive or mucosa.

Dermatitis in children under 1 month of age.

Not used for ophthalmology.

Be cautious when using

Do not use birth control pills, because in these cases, salicylic acid activity can increase steroid absorption.

If there is a phenomenon of non -tolerated on the spot, it is necessary to stop treatment.

The drug is only used externally, avoiding applied to the mouth, eyes, mucosa, avoiding applying the drug to a large or under the iron and applying it into a thick layer.

Do not treat continuously for more than 8 days.

During the long -term corticosteroid therapy, regular monitoring of patients must be monitored.

For psoriasis: Local corticosteroid drugs can be dangerous for psoriasis, the risk of recurrence when stopping the drug, the risk of transforming into pumbles with pustules of the body and the risk of skin infections due to weakened skin barriers. Careful monitoring for patients treat psoriasis. If the skin is dry or increased skin irritation, stop using the drug.

Betamethasone dipropionate and salicylic acid absorption may increase when taking drugs on wide or under sealed skin in a long time or with too much steroids. In these cases, it is necessary to take appropriate preventive measures, especially for babies and young children.

Any side effects have been reported after using systemic corticosteroids, including adrenal inhibitors, which can also occur with topical corticosteroids, especially in infants and young children.

visual disorders may have been reported when using systemic corticosteroids. If symptoms appear such as fuzzy vision or other visual disorders, the doctor should immediately find the cause. Long -term use of corticosteroids can cause cataracts under the bag (especially in children), glaucoma can cause harm to the eye nerves and can increase the infection of fungal or secondary viruses in the eye.

Use for children:

Should be avoided in breastfeeding. Dosage in children should be limited to 5 days. It is necessary to be very careful when using Betasalic skin ointment on a large scale or damaged skin or prolonged use or tape for children, because the drug can be absorbed, causing inhibition of hill -shaft function - pituitary gland - adrenal gland (HPA axis) leads to undesirable effects. Reported in children using local corticosteroids. The manifestations of adrenal insufficiency in children include low cortisol levels in plasma and non -response to ACTH stimulation. The manifestations of increased intracranial pressure include swelling, headache and thorns on both sides.

The ability to drive and operate machinery

There has been no research on the effects of the drug on the ability to operate machinery, driving train, higher people working and other cases for topical drugs on Betamethasone skin.

Pregnancy

Salicylic acid can be absorbed in the body but very little. There is no restriction on using this drug for pregnant people.

Use corticosteroids during pregnancy or in people who are likely to consider the benefits and risks of the drug on the mother and embryo or fetus.

There was a weight loss in newborns when the mother was treated with long -term corticosteroids. Because of the ability to inhibit the adrenal shell in a newborn child because the mother has used long -term corticosteroids, when prescribing corticosteroids, they must consider the needs of the mother and the risk of the fetus. Babies that mothers have used corticosteroid doses significantly during pregnancy must be carefully monitored about the signs of adrenal gland reduction.

breastfeeding period

Salicylic acid is unlimited for nursing mothers.

Betamethasone Exports into breast milk and can be harmful to children because the drug can inhibit development and cause other unwanted effects, such as reducing adrenal gland function. Benefits for mothers must be considered with the ability to harm children.

However, do not apply medicine around the breast to avoid children swallowing the drug.

Drug interaction

with high doses of paracetamol or acting field: Increased risk of liver toxicity.

With oral or insulin diabetes treatments: can increase blood glucose levels.

With glycoside digitalis: may increase the possibility of arrhythmia or toxicity of digitalis and hypotension.

With phenobarbital, phenytoin, rifampicin or ephedrine: can increase metabolism and reduce the treatment effect of betamethasone.

With anticoagulants of COMAIN: can increase or decrease anticoagulant effects.

Storage

Store in a dry place, avoid light, temperature below 30 ° C.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.