Betoptic S alcon eye drops treat glaucoma, chronic open -angle glaucoma (5ml)
Dosage form Bottle x 5ml
Specifications Betaxolol hydrochloride
Ingredient Glocom glaucoma
Ingredient
| Composition information | Content |
| Betaxolol hydrochloride | 2.5mg/ml |
Uses
Indications
Betoptic medicine is indicated in the following cases: Betoptic sterile eye media has the effect of lowering pressure and is indicated for patients with chronic open -angle glaucoma and glaucoma.
Pharmacokology
betaxolol hydrochloride, beta-1-adrenergic receptor inhibitor in the heart, no significant membrane stability (local anesthesia) and no internal sympathetic activity. After the eyes are small, the Betoptic eye is small, reduces the internal pressure both as usual as well as when the internal pressure increases, whether or not it is accompanied by glaucoma.
The mechanism of effectively lowering the pressure is shown by a decrease in the production of aquaculture that is shown by the pressure of the pressure and the aquarium measurement by Fiuorophotometry optical measurement method. The beginning of the effect of the small Betoptic eye is usually recorded within 30 minutes and achieves the maximum effect after 2 hours of eye small. Using the only dose reduces internal pressure in 12 hours.
The effect of Betoptic eye is as a neurological protection shown in both In Vivo and Vito tests on rabbit retinal retinal, mouse cerebral culture and chicken retinal culture.
pharmacokinetics
betaxolol dissolved in fat so it penetrates well into the cornea, giving a high level of intraocular drug.
Betaxolol has good oral absorption, low initial transformation and has a long selling time, corresponding to about 16 - 22 hours. Betaxolol is mainly eliminated by the kidneys, not in feces. The main conversion path into two types of carboxylic acid and constant form in urine (about 16% dose).
The effect of betaxalol usually appears within 30 minutes and the maximum effect appears after 2 hours of taking the medication on the spot. A single dose has the effect of lowering internal pressure in 12 hours.
The extreme nature of Betaxolol creates a clear discomfort in the eye. In this formula, Betaxolol binds the ion to Amberlite ion exchange resin. When the drug is small, the betaxolol molecules are replaced with ions in the tear film. This replacement process takes place for a few minutes and makes the eyes more comfortable.
Before taking Betoptic S alcon eye drops treat glaucoma, chronic open -angle glaucoma (5ml)
How to use
only use to shake eyes, shake well before use.
Dosage
adults (including elderly patients)
recommended dose is 1 drop into the eye 2 times/day. In some patients, it may take a few weeks after treatment with Betoptic eye media to respond to stabilization. Caution should be monitored in glaucoma patients.
If the intraocular pressure is not controlled when using a betoptic eye, combined therapy with pilocarpin, other pupils or adrenalin (epinephrin) and carbonic inhibitors can be prescribed.
Children
Safety and effective treatment in children have not been established.
The volume of each drop is 25µl.
When pressed on the pipe or closed your eyes for 2 minutes after small eyes, the whole body absorption of the drug will decrease. This will help reduce the unwanted effects of the whole body and increase the local effects of the drug.
After opening the lid, if the attachment is removed, it is necessary to remove it before taking the drug.
Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.
What to do when overdose?
If an overdose occurs with a small Betoptic eye mixture, symptomatic treatment and supportive treatment should be treated.
What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.
Side Effects
When using Betoptic medicine, you may experience unwanted effects (ADR).
Common, ADR> 1/100
Uncommon, 1/1000 Respiratory disorders, chest and mediastinum: asthma, shortness of breath, rhinitis. Rare, ADR Eye disorders: cataracts. Respiratory disorders, chest and mediastinum: cough, runny nose. Instructions on how to handle ADR When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.
Warnings
Before using the drug you need to read the instructions carefully and refer to the information below.
Contraindicated
Betoptic drug contraindicated in the following cases:
Respiratory respiratory disease includes severe bronchial asthma or a history of severe bronchial asthma, chronic obstructive pulmonary disease. Slow sinus rhythm, atrial block of level 2, 3, clear heart failure or cardiac shock. Caution Like other eye medications, Betaxolol is absorbed the whole body. Because the betaxolol is a beta-adrenergic blocker, which can occur unwanted effects on the heart, lungs and other unwanted effects as observed with beta-adrenergic blockers using systemic sugar. The incidence of adverse adverse reactions after local medication is lower when using systemic sugar. To reduce the whole body absorption, see the dose section and how to use. Precautions when using
In patients with cardiovascular disease (such as coronary artery disease, prinzmetal and heart failure) and hypotension, the treatment for beta blockers should be carefully evaluated and should be considered for treatment with other active ingredients. Patients with cardiovascular diseases should be monitored the signs of worsening of these diseases and adverse effects. Stop treatment with Betoptic mixture when signs of first heart failure.
Due to the adverse effect on the transmission time, it is careful to use the beta blockers in patients with atrial atrial level 1.
circuit disorders
Be cautious when treating drugs for patients with disturbance/severe peripheral circulatory disorders (such as severe forms of Raynaud or Raynaud's syndrome).
Respiratory disorders
Respiratory reactions, including death from bronchospasm in patients with asthma that have been reported after taking some beta blockers.
Hypoglycemia/diabetes
Be cautious when taking beta blockers for spontaneous hypoglycemia patients or unstable diabetes due to beta blockers can hide signs and symptoms of acute hypoglycemia.
hyperthyroidism
Beta blockers can also hide the signs of hyperthyroidism. Patients suspected of developing thyroid poisoning should be carefully managed to avoid stopping the adrenergic beta blockers because they can cause hyperthyroidism.
weakness
The beta-adrenergic blockers that have been reported can cause muscle weakness in the symptoms of myasthenia gravis (for example, the might, mi-eyelids and body weakness).
corneal disease
In patients with glaucoma closed angle, the immediate treatment goal is to open the angle by having a pupil with a drug that has a pupil. Betaxolol has little or no effect on pupils.
When using Betoptic mixture to reduce internal pressure increased in patients with glaucoma closed angle, it should be combined with a pupil and not used.
Using beta blockers in the eye can dry out the eyes. Be careful when using beta blockers in patients with corneal disease, sicca syndrome or abnormalities in tears film.
Other beta blockers
Effect of lowering intraocular pressure or body blockade effects that can occur when using betaxolol in patients who have been treated with all -body beta blockers. Need to closely monitor the response of these patients. It is not recommended to use two beta-adrenergic blockers.
Hypersensitivity reaction
While taking beta blockers, patients with a history of allergies or hypersensitivity reactions with some allergens may react more strongly to the repetitive challenge with these allergens and may not respond to the common adrenalin dose used to treat hypersensitivity reactions.
circuit peeling
The vein has been reported when using fluid inhibitors (for example, Timolol, Acetozolamid) after filtration.
surgical anesthesia
Beta blockers can inhibit the effects of the whole Beta as adrenalin.
Should notify the anesthetic doctor when patients use betaxolol. Slowly consider stopping the β-adrenergic blockers before the body anesthesia due to the reduction of the heart's ability to respond to β-adrenergic reflex stimuli.
contact lenses
Betoptic eye -catching chemicals containing benzalkonium chloride can cause irritation and change the color of soft contact lenses. Avoid contact with soft contact lenses. Patients need to be instructed to remove contact lenses before the Betoptic eye is small and wait at least 15 minutes before wearing again.
The ability to drive and operate machinery
temporary blurring vision or other visual disorders may affect the ability to drive or use machinery. If blurred vision appears after small eyes, the patient must wait until it is clear and then drove or used machines.
Pregnancy
There is no adequate data on the use of betaxolol in pregnant women.
Epidemiological studies do not show malformations but show the risk of postpartum development in the uterus when the mother uses oral beta blockers. In addition, the signs and symptoms of beta blockers (such as slow heartbeat, hemorrhage, respiratory failure and hypoglycemia) have been observed in the emulsion when the beta blockers are used for mothers until birth.
Do not use betaxolol during pregnancy unless really necessary. However, if the Betoptic eye is used until birth, children should be carefully monitored during the first days of birth.
Breastfeeding period
Beta blockers are excreted into breast milk, which can cause serious unwanted effects in infants to breastfeed. However, at the betaxolol treatment dose in eye drops, the amount of medicine in breast milk may not be enough to cause clinical symptoms of beta blockers in infants.
Drug interaction
may have a synergistic effect that leads to significant hypotension or a significant heart rate slow when using beta-blocked eye-catching solutions with calcium channel blockers, beta-adrenergic blockers, anti-arrhythmic drugs (including amiodaron) or glycosides cardiocardia.
Beta blockers can reduce response to adrenalin used to treat hypersensitivity reactions. It is necessary to be especially cautious in patients with a history of allergies or anaphylaxis.
Storage
Store drugs at temperatures not exceeding 30 ° C.
Keep the vial in the drug box.
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