Bonlutin Catalent reduces symptoms of mild and medium knee osteoarthritis (4 blisters x 15 tablets)

Dosage form Soft capsules
Specifications Box of 4 blisters x 15 tablets
Ingredient Fish oil, glucosamine, chondroitin sulfate
Indication Knee osteoarthritis
Contraindication Pregnancy, food allergies, drug allergies

Ingredient

Composition information	Content
Fish Oil	500mg
Glucosamine	500mg
Chondroitin sulfate	11.1mg

Uses

Indications

Bonlutin drugs are indicated to reduce symptoms of mild and medium knee osteoarthritis.

Pharmacokology

Glucosamine is an amino monosaccharide used in the biosynthesis of molecules containing articular cartilage. Glucosamine plays a combined role, reproduces cartilage, has anti -inflammatory effects.

chondroitin sulphate is a block of proteoglycan molecules in cartilage tissue. Chondroitin Sulphate is seen as an influence on the formation of new cartilage by stimulating the metabolism of cartilage cells and collagen proteoglycan synthesis.

Inflammatory reactions related to Prostaglandins and Leukotrienes. Omega - 3 fatty acids have anti -inflammatory effects thanks to the ability to inhibit the synthesis of inflammatory substances (inhibiting Leukotriene synthesis).

pharmacokinetic

glucosamine is absorbed from the small intestine. The bioavailability of oral glucosamine sulphate is 26%, glucosamine is metabolized for the first time through the liver. Glucosamine is excreted mainly in the urine, and a small amount is eliminated through feces.

chondroitin sulphate is eliminated largely through urine. Oral bioavailability is 7 - 12%, plasma concentration reaches the maximum after about 190 minutes and the sale time is 6 hours.

Plasma EPA concentration increases depending on the dose. Plasma DHA concentration can be compared to all research doses. The rapid increase in EPA and DHA plasma concentrations are recorded in all doses. The EPA is more accumulated during the absorption of high doses of fish oil rather than low doses. In the "cleaning" stage, there is a rapid change in the amount of EPA and DHA to the original point. Omega-3 fatty acids through a diet integrated in fat tissues.

Before taking Bonlutin Catalent reduces symptoms of mild and medium knee osteoarthritis (4 blisters x 15 tablets)

How to use

oral medication. Bonlutin taken for or after meals.

Dosage

Adults:

Take 2 capsules/time, 2-3 times/day, or as directed by the doctor.

Time to use the drug depending on the patient, at least use continuously for 2 to 3 months to ensure the effectiveness of treatment.

Children:

Dosage for children has not been reported.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Using more drugs will not improve your symptoms; Instead they can cause poisoning or serious side effects. If you suspect that you or anyone else may have overdosed Bonlutin, please go to the emergency room at the nearest hospital or hospital. Carry a box, shell, or a pharmacy with you to help doctors have the necessary information.

Do not give your medicine to others even though you know they have the same disease or look like they may have the same disease. This can lead to overdose.

Please consult your doctor or pharmacist or product package for more information.

There is no report on overdose of Bonlutin.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

There has been no report on side effects of Bonlutin. However, other side effects may still occur. If you encounter any unwanted effect, stop taking the medication and immediately notify your doctor or immediately go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Bonlutin drugs contraindicated with:

Patients sensitive to any ingredients of the drug.

Precautions when taking medicine

Please read the instructions carefully before use.

Products derived from seafood, people allergic to seafood should be careful when taking the drug.

Each capsule contains 64.6 mg of potassium, people with kidney disease or are taking cardiovascular medication, blood pressure should consult a doctor before taking this medication.

The ability to drive and operate machinery

There has been no report on the effect of Bonlutin drug on driving and operating machinery. However, when using the drug that has sleepy, headache, you should be careful.

Pregnancy and lactation

Pregnancy:

It is not known whether Bonlutin is safe for pregnant women. If necessary, please consult a doctor, medical expert to consider the benefits before use.

Breastfeeding period:

It is still not known whether Bonlutin will affect breastfeeding women. If necessary, you should consult a doctor and pharmacist to consider the benefits of the mother and the risk of children. You can or stop taking medication or stop breastfeeding.

Other special subjects

adolescents under 18 years of age or less because there is no data on safety and effectiveness. If the use is necessary, please consult a doctor and pharmacist to consider the benefits and risks.

Medicinal interaction

Medicinal interaction can change the ability of the drug or increase the effects of side effects. It is best to write a list of drugs you are taking (including prescription, non -prescription and functional foods) and for doctors or pharmacists. Do not arbitrarily take the drug, stop or change the dosage of the drug without the permission of the doctor, especially:

People with kidney disease.Does

food and alcohol interact with Bonlutin?

Please consult your doctor about taking medicine with food, alcohol and tobacco.

What health condition affects Bonlutin?

Your health status may affect the use of this drug. Tell your doctor if you have any health problems.

Storage

You should store at room temperature, avoid moisture and avoid light. No storage in the bathroom or in the freezer. You should remember that each drug may have different storage methods. Therefore, you should read carefully storage instructions on the packaging or ask the pharmacist.

Keep pills out of reach of children and pets.

Expiry date: 36 months from the date of manufacture.

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Disclaimer

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