Brapanto 40mg Deva medicine treats peptic ulcer (4 blisters x 7 tablets)

Dosage form Box of 4 blisters x 7 tablets
Specifications Pantoprazole
Ingredient Peptic ulcer, gastroesophageal reflux

Ingredient

Composition information	Content
Pantoprazole	40mg

Uses

indications

Brapanto 40 mg is indicated in the following cases:

Gastroenter ulcer. In terms of chemical structure is the derivative of benzimidazol.

specific inhibitors and not restoring proton pumps due to the selection effect on the gastric cell wall, the drug works faster and more effectively than other drugs. The scarring rate (healing of ulcers) can reach 95% after 8 weeks of treatment. The drug has little effect on the volume of gastric juice, pepsin secretion, stomach element and gastric contractions.

Pharmacokinetics

absorption

Pantoprazol quickly absorbed through the gastrointestinal tract, but varies depending on the dose and stomach pH. Oral bioavailability can be up to 70% if used repeated.

Distribution

Pantoprazol is strongly attached to plasma proteins.

Metabolism

Metabolic drugs in the liver.

Elimination

Eliminate drugs through the kidneys 80%, the sale time is about 30-90 minutes.

Before taking Brapanto 40mg Deva medicine treats peptic ulcer (4 blisters x 7 tablets)

How to use

Take oral use.

Do not chew or crush pantoprazole but have to drink whole tablets with water, an hour before breakfast. In Helicobacter Pylori, need to take the second pantoprazole tablet before dinner.

In general, combined therapy only needs 7 days to treat Helicobacter pylori and heal ulcers.

Dosage

Patients with stomach and duodenal ulcers, Helicobacter pylori infection (positive)

Need to kill bacteria by combined therapy. Depending on the type of drug resistance, it is possible to follow the following combination diagrams to kill Helicobacter pylori:

Regimen 1: 2 times a day x (1 pantoprazole + 1000 mg amoxicylline + 500 mg Clarithromycine) x 7 days.

Regimen 2: 2 times a day x (1 pantoprazole + 500 mg metronidazol + 500 mg Clarithromycine) x 7 days.

Regimen 3: 2 times a day x (1 pantoprazole + 1000 mg of amoxicilline + 500 mg of metronidazol) x 7 days.

Gastroesophageal reflux disease (GERD)

1 tablet of 40 mg/day.

Patients with severe liver failure

Dosage should be reduced to 1 tablet (40 mg of pantoprazole), every two days.

In addition, for these patients, liver enzymes should be monitored in Pantoprazole. If the liver enzyme value increases, pantoprazole should be discontinued.

Recognizing kidney failure

Do not use 40 mg of pantoprazole one day in older people or kidney failure. The exception is the combination of Helicobacter pylori, in which the elderly must also use the normal pantoprazole doses (2 x 40 mg/day) in a week of treatment.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when using overdose?

What to do when you forget 1 dose?

Side Effects

When using Brapanto 40 mg, you may experience unwanted effects (ADR).

Treatment with Pantoprazole may occasionally have a headache or mild diarrhea and more rare cases such as nausea, upper abdominal pain, flatulence, skin rash, itching and dizziness. Some rare cases occur such as edema, fever, thrombosis.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Brapanto 40 mg is contraindicated in the following cases:

Do not use pantoprazole for cases where a history of sensitive to pantoprazole.

Clinical experience of pantoprazole when used during pregnancy is still limited.

There is no information on Pantoprazole's output through breast milk. Only use Pantoprazole when the benefit of the mother is considered greater than the risk for the fetus and the baby.

Be cautious when using

recommendations to use injection when used orally inappropriate.

Before treatment with Pantoprazole, it is necessary to eliminate malignant stomach or malignant gastroenteritis, because it may temporarily overshadow the symptoms of malignant ulcer, so it can slow down the diagnosis.

There is no experience in treating Pantoprazole in children.

The ability to drive and operate machinery

is currently unclear the effect of the drug when used for drivers or operating machinery.

Pregnancy

The drug used during pregnancy can cause bad effects (miscarriage, monster, fetal defects ...) to any stage of development of pregnancy, especially in the first three months. Therefore, it is best not to take medicine for pregnant women. In case of compulsory use, it is necessary to carefully consult the doctor and pharmacist before deciding.

The period of breastfeeding

The drug can be transmitted through the baby through breastfeeding. It is best not to use or limit the medication during breastfeeding. Many drugs have not yet determined the effects of the drug during this period, mothers need to read the instructions for use and consult the doctor and pharmacist before deciding to take the drug.

Drug interaction

pantoprazole may reduce the absorption of other drugs used at the same time that the absorption depends on pH (for example: ketoconazole). This also occurs with drugs used before Pantoprazole for a short time.

The active ingredient of Pantoprazole is metabolized in the liver thanks to the cytochrome P450 enzyme system. It does not exclude the possibility of pantoprazole interacting with other drugs metabolic and cytochrome P450 enzyme system. However, the clinical clinical has not seen significant interactions in specific tests with some of the above -mentioned drugs or compounds, such as carbamazepine, caffeine, diazepam, diclofenac, digoxine, ethanol, glibenclamide, metoprolol, nifedipine, phenprocoumon, phenytoin, theophyline, warfarine and warfarine drugs and utility drink.

also do not see pantoprazole interacting with antacids (treat stomach pain) when taken at the same time.

There is no interaction with antibiotics used in combination (clarithromycine, metronidazol, amoxicylline) in the treatment of Helicobacter pylori.

Storage

Store at temperatures below 25 ° C.

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