Bromhexin 4mg medicine 3-2 dissolves in bronchitis, chronic bronchitis (10 blisters x 20 tablets)

Dosage form Tablet
Specifications Box of 10 blisters x 20 tablets
Ingredient Bromhexine
Indication Coughing with phlegm, pulmonary, acute bronchitis, bronchiectasis, chronic obstructive pulmonary, chronic bronchitis
Contraindication Peptic ulcer, bronchial asthma

Ingredient

Composition information	Content
Bromhexine	4mg

Uses

indications

Bromhexine 4mg drugs are indicated in the following cases:

Melting sputum in bronchitis, chronic bronchitis, chronic bronchial diseases. Bromhexin is often used as a supplement with antibiotics when suffered from severe respiratory infections.

Pharmacokic

Bromhexin hydrochloride is a regulating and respiratory mucus. Due to the activation of sialomucin synthesis and breaking the acid mucopolysaccharid fibers, the drug makes the sputum more liquid and less. The drug makes phlegm easier, so the sputum should be exhausted effectively.

When drinking, it usually takes 2-3 days to show clinical effects.

Dynamic pharmacokinetics

bromhexin hydrochloride quickly absorbed through the digestive tract and initially metabolized in the liver very strong, so bioavailability when drinking only reaches 20-25%. Food increases the bioavailability of Bromhexin hydrochloride. Peak concentration in plasma, in healthy volunteers, achieved after drinking, from half an hour to 1 hour.

Bromhexin hydrochloride is widely distributed into the body's tissues. The drug is very strong (over 95%) with plasma protein.

Bromhexin is metabolized mainly in the liver. There has been detected at least 10 metabolites in plasma, in which, ambrosol is a metabolite that is still active. Half of the lifetime elimination of the drug in the last phase is 12 - 30 hours depending on the individual, because in the first phase, the drug is heavily distributed into the body's tissues. Bromhexin passes through the brain barrier, and a small amount passes the placenta in the fetus.

About 85 - 90% of the dose is deducted from urine, mainly in the form of metabolites, after being associated with sulfuric acid or glycuronic acid and a small amount is excreted. Bromhexin is excreted in very little fertilizer, only about 4%.

Before taking Bromhexin 4mg medicine 3-2 dissolves in bronchitis, chronic bronchitis (10 blisters x 20 tablets)

How to use

bromhexin 4mg is used by oral.

Dosage

Adults and children over 10 years old: Take 2 capsules each time, 3 times a day.

Children 5 -10 years old: Take 1 tablet each time, 3 times a day.

Children 2-5 years old: Take 1/2 tablet each time, 3 times a day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? If an overdose occurs, symptomatic treatment and support.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using 4mg bromhexin, you may experience unwanted effects (ADR).

Rare, ADR

Digestive system: digestive disorders.

skin: skin allergies

Respiratory: The risk of stagnant in the bronchus in some patients cannot spare themselves.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Bromhexin 4mg contraindications in the following cases:

Patients sensitive to bromhexin or other ingredients of the drug.

First 3 months of pregnancy and nursing women.

Caution when using

while using bromhexin should avoid coordination with cough drugs because of the risk of sputum stagnation in the respiratory tract.

bromhexin, due to the effect of eliminating mucus, can cause damage to the stomach mucosa; Therefore, when used for patients with a history of stomach ulcer must be very cautious.

Be careful when used for asthma patients, because bromhexin can cause bronchospasm in some sensitive people.

Bromhexin clearance and metabolites may be reduced in patients with severe liver or renal failure, so it is necessary to be cautious and monitor.

Be careful when using bromhexin for the elderly or weakness, too weak is unable to sput up effectively, thus increasing phlegm.

The ability to drive and operate machinery

does not affect.

Pregnancy

Not used for pregnant women in the first 3 months and nursing women.

breastfeeding period

Not used for breastfeeding women.

Drug interaction

does not coordinate with drugs that reduce the secretion (reducing bronchial secretion) such as Atropine -style drugs (or anticholinergic) because of the effect of bromhexin.

Do not coordinate with anti -cough drugs.

Use bromhexin combination with antibiotics (amoxicillin, cefuroxim , erythromycin, doxycycline ) increase antibiotic concentration into lung and bronchial. Thus, bromhexin can act as a supplement in the treatment of respiratory infections, increasing the effects of antibiotics.

Storage

Leave in a dry place, temperatures below 30 ° C, avoid light.

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