Bromhexin 8mg medicine 3-2 dissolves in bronchitis, chronic bronchitis (10 blisters x 20 tablets)

Dosage form Tablet
Specifications Box of 10 blisters x 20 tablets
Ingredient Bromhexine
Indication Coughing with phlegm, pulmonary, acute bronchitis, bronchiectasis, chronic obstructive pulmonary, chronic bronchitis
Contraindication Peptic ulcer

Ingredient

Composition information	Content
Bromhexine	8mg

Uses

Indications

Bromhexin drugs are indicated in the following cases:

Dissolve phlegm in bronchitis.

Chronic bronchitis. Hydrochorid is a regulation and respiratory mucus. Due to the activation of sialomucin synthesis and breaking the acid mucopolysaccharid fibers, the drug makes the sputum more dilute and less. The drug makes phlegm easier, so the sputum should be exhausted effectively.

When drinking, it usually takes 2-3 days to show clinical effects.

pharmacokinetics

Bromhexin hydrochloride quickly absorbed through the gastrointestinal tract and is initially metabolized in the liver very strong, so bioavailability only reaches 20-25%. Food increases the bioavailability of Bromhexin hydrochloride. Peak concentration in plasma, in healthy volunteers, achieved after drinking, from half an hour to 1 hour.

Bromhexin hydrochloride is widely distributed into the body's tissues. The drug is very strong (over 95%) with plasma protein.

Bromhexin is metabolized mainly in the liver. There has been a detection of at least 10 metabolites in plasma, in which, ambroxol is a metabolite that is still active. Half of the lifetime elimination of the drug in the last phase is 12 - 30 hours depending on the individual, because in the first phase, the drug is much distributed into the body's tissues. Bromhexin passes through the brain barrier, and a small amount passes the placenta in the fetus.

About 85 - 90% of the dose is eliminated in the urine, mainly in the form of metabolic substances, after being associated with sulfuric acid or glucuronic acid and a small amount is excreted. Bromhexin is excreted in very little fertilizer, only about 4%.

Before taking Bromhexin 8mg medicine 3-2 dissolves in bronchitis, chronic bronchitis (10 blisters x 20 tablets)

How to use

bromhexin is recommended orally with a cup of water.

Dosage

normal bromhexin dose for adults and children over 10 years old: take 1 tablet at a time, 3 times a day.

Normal dosage of bromhexin for children 5 - 10 years old: Take ½ tablet, 3 times a day.

Dosage may vary for each patient. The dose you take depends on your age, health and other conditions. Talk to your doctor or your doctor about your appropriate dosage.

What do

do when overdose? If an overdose occurs, symptomatic treatment and support.

What to do when you forget the dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

In case of emergency or overdose, immediately call the 115 emergency center or visit the nearest local health station.

Side Effects

When using bromhexin you may experience unwanted effects (ADR).

Rare side effects such as:

digestive disorders.

allergies on the skin. In addition, some other side effects can also occur. In the process of using the product, if the patient sees the side effects or any abnormal symptoms, it is advisable to go to the nearest medical facility center to get the advice from the treating doctor, the pharmacist and the medical staff.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Bromhexin drugs are contraindicated in the following cases:

Patients sensitive to bromhexin or other ingredients of the drug.

Be cautious when using

while using bromhexin should avoid coordination with cough medicine because there is the risk of sputum stagnation in the respiratory tract.

Bromhexin, due to the effect of eliminating mucus, can cause damage to the stomach mucosa, so when used for patients with a history of stomach ulcer must be very cautious.

Be careful when used for asthma patients, because bromhexin can cause bronchospasm in some sensitive people.

Bromhexin clearance and metabolites may be reduced in patients with severe liver or renal failure, so it is necessary to be cautious and monitor.

Be careful when using bromhexin for the elderly or weakness, too weak is unable to sput up effectively, thus increasing phlegm.

The product should be removed after using up the number of use on the label or more than 2 months after opening the lid because the dose may no longer guarantee.

Use the right dose, do not increase or decrease the dose, as this can cause hypersensory reactions, or reduce product treatment effect.

To be out of reach of children to avoid the wrong product, it can cause serious damage to the digestive tract and cause a number of other diseases to the body. If there is a mistake, it is necessary to immediately take the child to a medical facility for timely treatment.

Patients do not arbitrarily stop the product but must listen to the doctor's advice, so gradually reduce the amount of amount, the arbitrary stopping the product can cause the body's immunity, and may increase the symptoms of some diseases.

When stopping using the product, it should be reduced slowly, not suddenly stopped. Do not put more than 2 consecutive doses.

The ability to drive and operate machinery

does not observe that it affects the ability to drive and operate machinery.

Pregnancy and lactation

Do not use for pregnant women in the first 3 months and nursing women.

Drug interaction

Do not coordinate with the drug to reduce the secretion (reducing bronchial secretion) such as Atropine -type drugs (or anticholinergic) because of the effect of bromhexin.

Do not coordinate with anti -cough drugs.

Use bromhexin combination with antibiotics (amoxicillin, cefuroxim, erythromycin, DoxycyCline) that increases antibiotic concentration into lung and bronchial tissue. Thus, bromhexin can act as a supplement in the treatment of respiratory infections, increasing the effects of antibiotics.

In the process of using the product, patients need to minimize foods or drinks containing alcohol or stimulants to avoid affecting the activity of the active ingredient.

Storage

Store drugs at less than 30 ° C, leave a cool dry place, avoid direct light, moisture prevention. Do not let the product in children can be with.

Notice the appearance of the product, if the product shell shows signs of openness, the product is discolored, watery or deformed, then do not use the product.

Expiry date: 36 months from the date of manufacture.

Manufacturer: Pharmaceutical Joint Stock Company 3/2 (F.T.Pharma).

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