Buclapoxime Brawn treats infection (1 blister x 10 tablets)

Dosage form Box of 1 blister x 10 tablets
Specifications Cefpodoxime
Ingredient Tonsillitis, pharyngitis, otitis media, sinusitis, urinary tract infections, skin and soft tissue infections, gonorrhea infections, pneumonia

Ingredient

Composition information	Content
Cefpodoxime	200mg

Uses

indications

Buclapoxime 200mg Brawn 1x10 is indicated in the following cases:

The drug is indicated in the treatment of infections caused by sensitive bacteria such as:

Inferred respiratory infections: Acute sinusitis, otitis media, tonsillitis, pharyngitis.

Lower respiratory infections: bronchitis, acute pneumonia and acute phase of chronic pneumonia, acquired pneumonia in the community. Invonient urinary tract infections.

Acute gonorrhea, inconstatable, endothelial cervical or anus - rectum of women and gonorrhea in the urethra of women and men.

Skin infections and structure of the skin.

Pharmacology

Cefpodoxim is an antibiotic of the 3rd generation cephalosporin group, which has bactericidal effects by inhibiting the synthesis of bacterial cell walls.

Active drugs on some of the following strains:

Gram (+) bacteria: Streptococcus pneumoniae, S. Pyogenes, S. Agalactiae, S. Mitis, S. Sangu and S. Salivarius; Propionibacterium acnes; Corynebacterium diphtheriae; S. AUS.

Gram bacteria (-): Haemophilus influenzae (including production strains and not producing beta-lactamase), Haemophilus para-influenzae, Moraxella Catatrhalis (Bravhanella Catatrhalis) and Nisseria Gonorrhoea, Escherichia COLOM; Klebsiella Pneumoniae, Klebsiella Oxytoca, Proteus Mirabilis.

Cefpodoxim Proxetil is a pre -pharmaceutical form of Cefpodoxim used orally. Cefpodoxim Proxetil has little antibacterial effect when not hydrolyzed into cefpodoxim in the body. Cefpodoxim Proxetil is absorbed through the digestive tract and is metabolized by na -specific esters, into a metabolite of Cefpodoxim.

pharmacokinetics

absorption:

Birth of Cefpodoxim is about 50%. This bioavailability increases when using Cefpodoxim with food.

Distribution:

About 40% Cefpodoxin binds to plasma proteins, the drug is eliminated in the form of unchanged through the filter of the glomerular and the excretion of the renal tubules.

Cefpodoxim's waste sale time is 2.1 - 2.8 hours for patients with normal kidney function and increases to 3.5 - 9.8 hours in people with kidney disabled after taking a dose of Cefpodoxim, in healthy adults with normal kidney function, plasma peak concentration is reached within 2-3 hours and has an average value of 1.4 microGam/ml, 2.5 micrograms Doses of 100 mg, 200 mg 400 mg.

About 29 - 38% of the dose is eliminated within 12 hours in adults with normal kidney function. There is no biological change in the kidneys and liver. The drug is eliminated to a certain extent when the hemorrhage.

Before taking Buclapoxime Brawn treats infection (1 blister x 10 tablets)

How to use

cefpodoxim should be used with food to increase the absorption capacity of the drug.

Dosage

adults and children over 13 years old:

Treatment of acute drama of chronic bronchitis or mild acute pneumonia to the community:

The usual dose of Cefpodoxim is 200 mg/time, every 12 hours, in 10 or 14 days, respectively.

Sore throat, mild tonsillitis to fit or infection of mild or incomplete urinary tract bacteria:

Cefpodoxim dose is 100 mg every 12 hours, for 5-10 days or 7 days, respectively.

Gonorrhea:

Use a single dose of 200 mg Cefpodoxim.

Skin infections and mild and medium -complicated skin organizations:

The common dose is 400 mg every 12 hours, for 7-14 days.

Children who are 13 years old:

Should use another form of preparation to suit the dose.

Patients with renal failure:

Creatinine clearance is less than 30 ml/min and no blood apart: The dose is commonly used at a distance of 24 hours.

Creatinine clearance is less than 30 ml/min and have a hemorrhage: The dose is often used at a distance of 3 times/week.

Elderly:

The efficiency and safety of Cefpodoxim on the elderly are equivalent to young people. Therefore, the dose of the elderly is the same as for young people.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when using overdose? However, it can cause hypersensitivity to the nervous system and seizure, especially in people with renal impairment.

When an overdose is encountered, the drug should be stopped immediately. Hemolysis can assist in eliminating Cefpodoxim from the body, especially in case of damaged kidney function.

In addition, it can be combined with symptomatic treatments and supporting the body's body.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using Buclapoxime 200mg Brawn 1x10 you can experience unwanted effects (ADR).

Rare, ADR

Blood and lymph: Prothrombin.

Unknown frequency

Digestive: diarrhea, abdominal pain, nausea and vomiting.

Sensitive reaction: Red rash, urticaria, itching, erythema, Stevens Jonhson reaction.

liver: Increase SGOT, SGPT transient and alkaline phosphatase.

kidney: interstitial nephritis has a recovery.

Central nervous system: headache or dizziness.

Blood and lymph: platelet reduction, leukopenia, eosinophilic hypernagus.

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Buclapoxime 200mg Brawn 1x10 contraindicated in the following cases:

Patients with hypersensitivity to Cefpodoxim antibiotics or other cephalosporins.

Patients with porphyrin metabolic disorders.

Be cautious when using

Patients who are sensitive to penicillin.

Patients with severe renal failure, pregnant women or breastfeeding.

The ability to drive and operate machinery

can be used when driving and operating machinery.

Pregnancy

Cephalosporin is often considered safe when used for pregnant women.

breastfeeding period

cefpodoxim is secreted through low concentrations. Despite low concentrations, there are still 3 problems that will occur for breastfed children with cefpodoxim: intestinal bacteria disorders, directly acting to the child's body and bacterial culture results will be wrong. Therefore, there should be regular monitoring of children's condition for appropriate adjustment.

Drug interaction

cefpodoxim is reduced absorption when anti -acid, so it should be avoided using Cefpodoxim with anti -acid.

With antihistamine H2: Cefpodoxim is reduced when used.

With probenecid: reducing the excretion of cefpodoxim through the kidney.

Drugs with kidney toxicity: When used simultaneously with Cefpodoxim, there is the ability to increase the toxicity of the kidneys of the same.

Storage

Store in a dry, cool place at temperatures below 30 ° C, avoiding light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.