Bunpil topical cream 10mg April treatment of skin fungus, tinea versicolor (15g)

Dosage form Cream
Specifications Box x 15g
Ingredient Terbinafine HCl

Ingredient

Composition information	Content
Terbinafine HCl	1%

Uses

indications

Bunpil drugs are indicated in the following cases:

Fungal skin, tinea and cantida fungal disease.

ATC code: D01AE15.

Terbinafin is a synthetic derivative of Allylamin with broad -spectrum anti -fungal activity. The drug prevents Ergosterol biosynthesis (the main component of the fungal cell membrane) due to inhibition of enzyme Squalen Monooxyhenase (Squalen 2.3-Epoxydase).

This leads to the accumulation of squalen (is the substance of the enzyme) in the fungal cell and the deficiency of sterol, especially Ergosterol in the fungal cell membrane, are the factors that cause fungal cell death.

Terbinafin has the effect of killing fungi or mushroom pliers depending on the concentration of drugs and experimental mushrooms. The drug has a fungal activity for many mushrooms, including skin fungus such as Trichophyton (eg trubrum, T.mentagrophytes, T.verrucosum), Microsporum Gypseum, Mnanum, Epidermophyton Flocosum, fibrosis such as Aspergillus; Mesopatotic mushrooms like blastomyces; Mold and yeast such as Candida Albicans, C.Parapsilosis and Scopularopsis Brevicaulis.

pharmacokinetics

in the human body, less than 5% of the dose is absorbed after applying the drug on the spot. Therefore, the whole body effect is very light. The metabolites through biological metabolism have no antifungal effects and are excreted mainly through feces and urine. The sale time is 17 hours. There is no evidence of drug accumulation.

Before taking Bunpil topical cream 10mg April treatment of skin fungus, tinea versicolor (15g)

How to use

topical skin.

Dosage

Adults and children ≥ 12 years:

Fungal fungal fungal disease: Apply medicine to the sick area, once a day, at least 1 week, not more than 4 weeks. ): Apply cream to the sick area, 1-2 times a day, for 2 weeks.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

overdose

Because terbinafin cream is topical, absorbing the whole body is very rare. In case of swallowing 30 g of Bunpil Cream cream (containing 300 mg of terbinafin hydrochloride), comparison is equivalent to a 250 mg Terbinafin (1 unit of adult oral dose).

If swallowing large amounts of Bunpil Cream, the expected side effects have similar symptoms to the side effects observed when overdose of terbinafin tablets. Symptoms include headache, nausea, epigastric pain and dizziness.

How to handle

If accidentally swallowed, recommended overdose management including removal (mainly by taking activated carbon) and providing supportive treatments for symptoms, if necessary.

In case of emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when you forget 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double doses to compensate for missed dose.

Side Effects

When using Bunpil, you may experience unwanted effects (ADR) such as:

Popular symptoms such as itching, peeling skin, pain, applicant irritation, pigment disorders, skin burning sensations, erythema and scales can appear at the position of medication.

The above mild symptoms must be distinguished from hypersensitivity reactions such as inflammation, rash, widespread rash that is reported on discrete but medical cases.

In case of eye contact, Terbinafin HCl can cause eye irritation.

In some rare cases, it may be worse than the initial fungal infection.

The adverse reactions are listed below by organ and frequency. The frequency is defined: Very common (≥ 1/10); Common (≥ 1/100 to

immune system disorders:

Unknown: Hypersensitivity.

Eyes:

Rare: eye irritation.

Skin and subcutaneous tissue disorders:

Common: peeling skin, itching.

Less: Pain, skin irritation at the position of drug use.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

contraindicated

Bunpil drugs contraindicated in the following cases:

Patients with a history of sensitivity to Terbinafin or any ingredients of the drug.

Be cautious when using

need to be very careful when taking the drug for patients in the following cases:

Avoid contact with the eyes as well as not in the vagina or drink. Also, avoid contact with the nose, mouth or other mucous membranes. It is recommended that patients avoid wearing tight clothes or closed ice. In case the drug is exposed to the eyes, it is necessary to wash the eyes under the flowing water. For candidiasis infections: Do not use soap with acid pH (acidic environment that facilitates Candida mushrooms to develop).

The effect of drugs on driving and operating machinery

does not affect.

Using drugs for women during pregnancy and lactation

Using drugs for pregnant women:

Studies on animal reproduction does not indicate any toxic effects of the drug, but no test test has been done in pregnant women. Therefore, drugs should not be used for pregnant women unless the benefits are superior to possible risks.

Use medicine for breastfeeding women:

Terbinafin is excreted through breast milk and although with low absorption, it is not recommended to take the drug during breastfeeding.

Interactive drug

No drug interaction is known for the cream cream bunpil cream.

Storage

Leave a cool place, avoid light, temperatures below 30⁰C.

To be out of reach of children, read the instructions carefully before use.

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