C-Calci OPC effervescent tablets and treatment of vitamin C and calcium deficiency (10 tablets)

Dosage form Effervescent
Specifications Tube 10 tablets
Ingredient Vitamin C, calcium carbonate
Indication Magic weakness, flu, osteoporosis, rickets
Contraindication Kidney stones, urinary stones, hypercalcemia, anemia due to enzyme deficiency G6PD, Thalassemia disease

Ingredient

Composition informationContent
Vitamin C1000mg
Calcium Carbonate600mg

Uses

indications

C-Calci 1000mg drug is indicated in the following cases: prevention and treatment of vitamin C and calcium deficiency.

Pharmacokinus

Vitamin C is necessary to synthesize collagen and components of connective tissue, which is reduced in many oxidation - reduction biological reactions, participating as a reducing agent in the drug metabolic enzyme system along with cytochrom P450. Some biological functions of vitamin C have been clearly defined include: collagen biosynthesis, carnitin, catecholamine, tyrosin, corticosteroids and aldosteron. Vitamin C also regulates absorption, transportation and reserves of iron and is an effective antioxidant protection.

Deficiency of vitamin C leads to scorbut disease, very rare in adults, but can be seen in young children, alcoholic or elderly. Deficiency in symptoms of bleeding easily (small blood vessels, gums), fragile capillaries, anemia, cartilage and bone damage, slowly seamless wounds. Use vitamin C completely losing the above symptoms.

Calcium is an important cell ion that is essential for many biological processes: neurotransmitter stimulating neuron, releasing neurotransmitters, muscle contraction, preserving membrane, blood clotting and helping the secondary transmission function for the activity of many hormones. On the cardiovascular system, calcium ions are essential for stimulating and constricting myocardial muscle as well as for electrical impulse transmission on some areas of the special heart muscle through the atrial node. On the muscular nervous system, calcium ions play an important role in stimulation and muscle contraction.

Lack of calcium occurs when the daily diet does not provide enough calcium, especially girls, the elderly, women before and after menopause and teenagers. Reducing blood calcium causes evidence: convulsions, tetani attacks, behavioral disorders and personality, growth retardation, brain retardation, bone deformation, especially rickets in children and bone puree in adults. Calcium supplementation is used as part of the prevention and treatment of osteoporosis in a non -calcium -eating person.

Dynamic pharmacokinetics

vitamin C

Absorption: Vitamin C is easily absorbed after drinking. Absorbing vitamin C in the stomach - intestines may be reduced in diarrhea or gastric disease.

Distribution: Vitamin C is widely distributed in body tissues. About 25% of vitamin C in plasma combined with protein. Ascorbic acid passes the placenta and is distributed in breast milk.

Metabolism and elimination: Vitamin C oxygen - Chemical reversible into dehydroorscorbic acid. A little vitamin C converted into non-activity compounds including ascorbic acid-2-sulfate and oxalic acid excreted in urine. The amount of vitamin C exceeding the body's requirements is also quickly excreted in the urine in the form of unchanged.

calcium

Absorption: The intestinal absorption in the intestine is inversely proportional to the amount of calcium eaten, a low -calcium diet leads to increased compensation, partly due to the impact of vitamin D. The level of absorption is significantly reduced by age. Diseases with fat stool, diarrhea, and chronic absorption in the intestine also increase calcium in the stool.

Elimination: Calcium is eliminated in the urine and is selected for the glomerular reabsorption (about 98% of calcium ions have been absorbed back to circulation). The reabsorption is adjusted by armor hormones, Na+filtration, the presence of non -reabsorbing ions, diuretic benefits. Calcium excreted quite a lot of milk during breastfeeding; A little calcium excreted through the assembly and also excreted through feces.

Before taking C-Calci OPC effervescent tablets and treatment of vitamin C and calcium deficiency (10 tablets)

How to use

Take oral use. Dissolve the pill in about 200 ml of water.

Dosage

Adults: Take 1 capsule 1 time/day.

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What do

do when overdose? Diuretic by infusion may work after a large dose.

Blood calcium concentration exceeds 2.6 mmol/liter (10.5 mg/100 ml), stop using any drug that is likely to cause hypercalcemia.

When serum calcium concentration exceeds 2.9 mmol/liter (12 mg/100 ml), it is necessary to immediately use the following measures: 0.9%sodium chloride solution. Making diuretic benefits with Furosemid or ethacrynic acid to quickly lower calcium and increase sodium elimination when using too many sodium chloride solutions 0.9%.

Monitor the concentration of potassium and magnesium in the blood, monitor the electrocardiogram (can use beta - adrenergic blockers to prevent heavy arrhythmia). Determine blood calcium concentration regularly for adjustment instructions for treatment. Hematomins can be used, using calcitonin and adrenocorticoids in treatment.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using C-Calci 1000mg, you may experience unwanted effects (ADR).

Not determined frequency

  • Kidney --ur urine: increased oxalate - urinary.
    • Digestive: Nausea, vomiting, heartburn, abdominal spasms.
  • nerve: headache, insomnia, drowsiness.
    • Cardiovascular: Hypotension, peripheral vessels, flushing. all body: tired.

    Instructions on how to handle ADR

    Notify the doctor the unwanted effects when used.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    contraindicated

    C-Calci 1000mg drug contraindicated in the following cases:

  • ventricular vibration in cardiac recovery, heart disease and kidney disease, hypercalcemia, malignant tumors destroy bone; Heavy calcium and osteoporosis due to immovable, patients are using digitalis, people with glucose-6-phosphate dehydrogenase deficiency (G6PD) (risk of hemolytic anemia).
  • Patients with hypersensitivity to any ingredients of the drug.

    • Be cautious when using

    use carefully with people with a history of kidney stones, increased oxalate urine and oxalate metabolic disorders (increased risk of kidney stones), thalassemia disease (increased risk of iron absorption), cases of respiratory failure or acidic infection, impaired people with renal function.

    Be cautious when using high doses, prolonged for pregnant women.

    When using a diet, use less or not use sodium salts, pay attention to each C-Calci 1000mg tablet contains about 211 mg of sodium.

    The ability to drive and operate machinery

    The drug does not affect the ability to drive and operate machinery.

    Pregnancy

    Vitamin C passes through the placenta, the blood concentration in the umbilical cord is 2-4 times the concentration of the mother's blood. If you use vitamin C according to your daily needs, there is no problem on people. However, taking large amounts of vitamin C during pregnancy can increase the need for vitamin C and lead to scorbut disease in infants.

    Calcium is not harmful when using daily daily needs.

    breastfeeding period

    vitamin C distributed in breast milk. Mother's milk has a normal diet containing 40 - 70 mcg vitamin C/ml, there has not been a problem that happens to babies.

    Calcium is not harmful when using daily daily needs.

    Drug interaction

    Unused C-Calci 1000mg with elemental iron, aspirin, fluhenazin, vitamin B12, selenium, thiazid, clopamid, ciprofloxacin, cloudidone, anti-seizure drugs, digoxin, glycosides cardiology.

    Because vitamin C is a strong reducing agent, it affects many tests based on oxidation - reduction.

    Storage

    The cool dry place, temperatures below 30 ° C. Close the lid immediately after use.

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