Cadicefdin 300 USP medicine for infection treatment (2 blisters x 10 tablets)

Dosage form Box of 2 blisters x 10 tablets
Specifications Cefdinir
Ingredient US Pharma

Ingredient

Composition information	Content
Cefdinir	300mg

Uses

indications

cadicefdin 300 drug is indicated in the following cases:

Indications for cases of mild to medium infections, caused by sensitive bacteria in the following cases:

Pneumonia with the community with the factors of Haemophilus Influenzae, Moraxella Catatrhalis (including seminarians Beta - Lactamase), Streptococcus pneumoniae (sensitive to penicillin).

Exacerbic phase of chronic bronchitis is also caused by Haemophilus Influenzae, Moraxella Catatrhalis (including Beta - Lactamase), Streptococcus pneumoniae (sensitive to penicillin).

Acute sinusitis caused by Haemophilus Influenzae, Moraxella Catnrhalis (including seminarians - lactamase) and Streptococcus pneumoniae (penicillin sensitive strain).

Pharyngitis/amydal inflammation due to streptococcus pyogenes.

Skin infections and skin structure: due to Staphylococcus aureus (including seminarians - lactamase) and streptococcus pyogenes.

Acute otitis media caused by Haemophilus Influenzae, Moraxella Catatrhalis (including seminarians Beta - Lactamase), Streptococcus pneumoniae.

Pharmacology

cefdinir is an antibiotic of the 3rd generation cephalosporin group.

The main substance of CadiceFDin 300 is Cefdinir, active on many types of gram -positive and gram -negative bacteria.

antibacterial spectrum includes

Gram -positive bacteria: Staphylococcus aureus, Staphyloccus Epidermidis (including seminarians beta lactamase but sensitive to methicilin), streptococcus pneumoniae, streptococcus pyogenes (sensitive to penicillin).

Staphylococcus aureus of methicilin, Enteroccocus, Enerobacter, Pseudomonas Aeruginosa is not sensitive to Cefdinir.

Gram -negative bacteria: Haemophilus Influenzae, Moraxella Catatrhalis, Escherichia Coli, Klebsiella Pneumoniae, Proteus Mirabilis, Neisseria Gonorrhoeae.

Mechanism of action

Cefdinir is a bactericidal by inhibiting the synthesis of bacterial cell wall, so bacteria cannot create cell walls and will be broken under the effect of osmotic pressure.

Pharmacokinetics

absorption

The maximum concentration of cefdinir in plasma appears after 2 to 4 hours after drinking. Cefdinir concentration in blood increases with dose but increases less at the dose from 300 mg (7mg/kg) to a dose of 600 mg (14 mg/kg). CEFDINIR's predictable bioavailability is 21% after taking the dose of 300 mg.

Distribution

The average distribution of CEFDinir in adults is 0.35 l/kg (± 0.29), in children (from 6 months to 12 years old) is 0.67 l/kg (± 0.38). Cefdinir is attached to plasma proteins from 60% to 70% in adults and children; Concentration does not depend on concentration.

Metabolism and elimination

Cefdinir metabolizes negligible. Cefdinir is excreted mainly through the kidney with an average selling time of 1.7 hours. In healthy people with normal kidney function, the clearance of the kidney is 2.0 (± 1.0) ml/min/kg and the clearance of the kidneys after taking the drug is 11.6 (± 6.0) after or taking the dose of 300 mg. The percentage of drugs excreted in the urine in the form of unchanged is 18.4% after taking the dose of 300 mg. Cefdinir clearance in patients with renal failure.

Before taking Cadicefdin 300 USP medicine for infection treatment (2 blisters x 10 tablets)

How to use

Take the whole pill.

Should take the medicine immediately after meals and at least 2 hours before or after using antacids or iron -containing preparations.

Dosage

Dosage and duration of use for each specific case as prescribed by the treating doctor. The usual dose is as follows:

Adults and children over 13 years old

Treatment time is from 5 to 10 days depending on the case, can be used once a day or divided 2 times/day.

300 mg x 2 times/day or 600 mg/day/day. The total dose is 600 mg for infections.

Patients with renal failure

Adults with creatinine clearance

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.What to do when overdose?

Dialycemia can eliminate Cefdinir from the body, especially in the case of kidney failure.

What to do when you forget a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Note that it should not be used double the prescribed dose.

Side Effects

When using cadicefdin 300, you may experience unwanted effects (ADR).

Side effects because Cefdinir is usually light, including:

rarely

diarrhea, nausea, headache, abdominal pain, rash, vaginitis.

Very rare

indigestion, flatulence, vomiting, anorexia, constipation, unusual feces, weakness, dizziness, insomnia, itching, sleeping chicken.

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

CADICEFDIN 300 drug is contraindicated in the following cases:

Patients with antibiotic cephalosporin or any ingredients of the drug.

Contraindicated in people allergies to penicillin.

Be cautious when using

as well as other broad -spectrum antibiotics, long -term treatment with Cefdinir can cause resistance bacteria. Need to monitor patients closely, if there is a phenomenon of re -infection during treatment, it is necessary to change to other antibiotics appropriately.

Be careful when used for patients with a history of colitis.

The ability to drive and operate machinery

There is no report on the impact of the drug on the ability to drive trains or operate machinery in references.

Pregnancy

There is no specific research in pregnant women, only taking the drug when really necessary.

The period of breastfeeding

There is no specific research in breastfeeding women, only taking the drug when necessary.

Interactive drug

Medications neutralizing gastric acid containing aluminum or magnesium and iron -containing preparations that reduce Cefdinir absorption. If it is necessary to take these drugs while being treated with cefdinir.

Probenecid: Like antibiotics Beta - Lactam other inhibits the excretion of the kidneys.

Storage

Store drugs in a dry place, temperatures below 30 ° C, avoid light.

Other drugs

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.