Calcium dhasan effervescent tablets treat osteoporosis, supplement calcium and vitamin D (18 tablets)

Dosage form Effervescent
Specifications Calcium carbonate, vitamin D3
Ingredient Osteoporosis, fracture, rickets

Ingredient

Composition informationContent
Calcium Carbonate1250mg
Vitamin D3440iu

Uses

Indications

Calcium dusan 18 v/tube is indicated in the following cases:

  • Preventing and treating osteoporosis in adults, rickets in children.

    • Pharmacy

    Caldihasan tablets containing calcium carbonate are the salt formula with the highest calcium concentration, the basic element that constitutes bones. Vitamin D3 supports the absorption of calcium into the body.

    calcium

    Calcium cans are essential for many biological processes: stimulating neurons, releasing neurotransmitters, muscle contraction, preserving membrane and coagulating. Calcium cans also help the secondary communication function for the activity of multiple hormones.

    On the cardiovascular system: Calcium ions are essential for stimulating and contracting myocardial as well as for electrical impulses on some areas of the heart muscle, especially through the atrial node.

    On the muscular nervous system: Calcium ions play an important role in stimulating and muscle contraction.

    cholecalciferol (Vitamin D3)

    Cholecalciferol (Vitamin D3) has the main function of maintaining normal calcium and phosphorus concentration in plasma by increasing the effectiveness of the absorption of minerals from diet, in the small intestine, increasing mobilization of calcium and phosphorus from bone to blood.

    pharmacokinetic pharmacokinetics

    calcium

    absorption:

    calcium is absorbed mainly through the small intestine thanks to the active transportation and passive diffusion mechanism. About 1/3 of calcium is absorbed, although this ratio may vary depending on the diet and small intestine. Vitamin D helps increase calcium absorption.

    Distribution and metabolism:

    99% of calcium in the body is concentrated in bones and teeth, the remaining 1% is distributed in intracellular and extracellular fluid. About 50% of calcium concentration in plasma in the form of ionization of physiological activity; About 5% form a complex with phosphate, citrate or other anion and the remaining 45% are linked to protein, mainly albumin.

    Era:

    The amount of calcium ions is discharged from urine depends on glomerular filtration and reabsorption in the renal tubules, more than 98% of the amount of calcium ion filtered through the glomerular reabsorption into the bloodstream. A significant amount of calcium is deducted from milk during breastfeeding, a part of sweat and stool.

    cholecalciferol (Vitamin D3)

    absorption:

    cholecalciferol is well absorbed through the gastrointestinal tract, mainly from the small intestine.

    Distribution and metabolism:

    cholecalciferol is hydroxylation in the liver forming 25 - hydroxycholeciferol. This substance continues to be hydroxylation in the kidneys to form a metabolism of 1.25 - dihydroxycholeciferol is active; This is a substance that increases calcium absorption. The non -metabolic part is stored in fat and muscle tissue.

    Era:

    cholecalciferol and its metabolites are excluded mainly through bile and feces, only a small amount appears in the urine.

    Before taking Calcium dhasan effervescent tablets treat osteoporosis, supplement calcium and vitamin D (18 tablets)

    How to use

    Oral drugs.

    Dosage

    Adults or children, depending on the needs of daily calcium.

    Take 1 - 2 capsules/day, take after eating or as directed by the doctor.

    Pregnant and lactating women: Do not use vitamin D more than 400 units/day.

    Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

    What to do when overdose?

    Symptoms:

    Anorexia, nausea, vomiting, constipation, abdominal pain, muscle weakness, mental disorders, thirst, multi -urinary, kidney calcium infection, arrhythmia and coma.

    Management:

    intravenously sodium chloride solution 0.9%. For forced diuretic in Furosemid or ethacrynic acid to increase calcium and sodium excretion when using too many sodium chloride solutions 0.09%. Monitor electrocardiograms and can use beta - adrenergic blockers to prevent heavy arrhythmia. Bloody stool can be used, Calcitonin and Adrenocorticoid can be used in treatment. Monitor the calcium concentration in the blood regularly.

    cholecalciferol (Vitamin D3)

    Symptoms:

    Anorexia, fatigue, nausea and vomiting, constipation or diarrhea, multi -urinary, night urine, sweating, headache, thirst, sleep, and dizziness.

    Management:

    Stop drugs, stop calcium supplements, maintain a diet with low calcium, drink plenty of water or infusion. Corticosteroids can be used or other drugs (such as Furosemid and Ethacrynic Acid), to reduce the calcium level in serum. Artificial kidney dialysis can be used or abdominal separation to release free calcium from the body. If vitamin D poisoning is acute, vitamin D can be prevented with vomiting or gastric lavage. If the drug has passed the stomach, treatment with mineral oil can promote vitamin D elimination through feces.

    What to do when forgetting 1 dose? However, if the time to relax with the next dose is too short, skip the dose and continue the calendar of the drug. Do not use double dose to compensate for missed dose.

    Side Effects

    When using Calci D Hasan 18 V/Tube, you may experience unwanted effects (ADR).

    Unknown frequency, ADR> 1/100

  • Neurological: Weak, tired, sleep, headache.
    • digestive: anorexia, dry mouth, metal flavor, nausea, vomiting, cramps in the abdomen, constipation, diarrhea, dizziness. Other effects: tinnitus, loss of air conditioning, foreign rash, reduced muscle tone, muscle pain, bone pain and easily stimulated.

    Instructions on how to handle ADR

    When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

    Warnings

    Before using the drug you need to read the instructions carefully and refer to the information below.

    Contraindicated

    Calcium dusan 18 V/Tube Contraindications in the following cases:

  • Hypersensitivity to the ingredients of the drug.
  • Diseases accompanied by blood hypercendrative syndrome (such as in patients with hyperthyroidism, overdose due to vitamin D, malignant bone resaulting, etc.), severe osteocurrent calcium hypercalci, kidney stones, ureteral stones, severe kidney failure, dynamic osteoporosis, is being treated with vitamin D.

    • Be cautious when using

    using too much calcium salts can lead to hypercalcemia.

    It is necessary to notify the doctor about the history of the disease, especially in diseases: Sarcoidosis) or the parathyroidism (which can cause increased sensitivity to vitamin D), kidney failure, a history of kidney stones, heart disease, atherosclerosis, liver disease, intestinal disease (Crohn's disease, whipple's), gastricular shortage ...

    Need to monitor calcium levels in blood and urine in patients with renal impairment, history of kidney stones ... or are using vitamin D if long -term treatment in these patients.

    Because the drug contains vitamin D, the use of more vitamin D needs medical monitoring to avoid overdose.

    Not used simultaneously with other supplements containing calcium and vitamin D.

    The ability to drive and operate machinery

    does not affect the ability to drive and operate machinery.

    Pregnancy

    If you use vitamin D at a larger dosage than the recommended daily daily dose (RDA dose) for normal pregnant people (400 ĐVQ/day) may occur risk. Therefore, Vitamin D should not be used at a larger dosage than RDA for pregnant women.

    Breastfeeding period

    Vitamin D is excreted in milk. Do not take the drug in a larger dose than the dose of RDA.

    Should only use drugs to supplement vitamin D and calcium if the diet is not enough or lack of ultraviolet radiation.

    Drug interaction

    should not treat CaldiHasan simultaneously with cholestyramin or colestypol hydrochloride (because it can lead to reduced vitamin D absorption); Phenobarbital, Phenytoin (increasing vitamin D conversion into non -active substances, reducing calcium absorption); corticosteroid (obstructing the effects of vitamin D), cardiac glycosides (toxicity of glycosides aids increased due to hypercalcemia, leading to arrhythmia).

    Simultaneous treatment of vitamin D with thiazid diuretics in people with parathyroidism can lead to hypercalcemia. Needs to reduce the dose or stop taking Vitamin D temporarily.

    Excessive use of mineral oil can also hinder the absorption of vitamin D through the gastrointestinal tract.

    Kidney inhibitors inhibitors: thiazid, clopamid, ciprofloxacin, chlorthalidon, anti -convulsions.

    Calcium reduces the absorption of Demeclocyclin, Doxycyclin, metacyclin, minocyclin, oxytetracyclin, tetracyclin, enoxacin, fleroxacin, levofloxacin, lomefloxacin, norfloxacin, ofloxacin, pefloxacin, iron, iron, iron, iron, and other substances.

    Diets with phytat, oxalate reduces calcium absorption because of creating difficult complexes to absorb.

    Storage

    Where dry, less than 30 ° C.

    Other drugs

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