Calcium Stella 500mg effervescent tablets and support for osteoporosis (20 tablets)

Dosage form Effervescent tablet
Specifications Tube 20 tablets
Ingredient Calcium Carbonate
Indication Osteoporosis, rickets
Contraindication Kidney stones, urinary stones, hypercalcemia

Ingredient

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Composition information	Content
Calcium Carbonate	500mg

Uses

Indications

Calcium stella 500mg is indicated in the following cases:

Prevention and treatment of calcium deficiency.

Additional calcium supplements support specific therapy in prevention and treatment.

Support for Vitamin D therapy, in the treatment of rickets and bone puree. Cation is an important activation factor in many enzymes reactions and is necessary for a number of biological processes including the transmission of nerve impulses; myocardial, smooth muscle contraction and skeletal muscle, kidney function; Respiratory and blood clotting. Calcium also plays the role of regulating the release and storage of nerve impulse and hormones, absorbing and connecting amino acids, absorbing cyanocobalamin (vitamin B12) and Gastrin secretion.

pharmacokinetic pharmacokinetics

absorption

Calcium is absorbed through the gastrointestinal tract by active transportation and passive diffusion. Calcium is actively absorbed in the duodenum and rosaries, and with inferiority in the farther sections of the small intestine. The level of absorption depends on a number of factors, calcium is not fully absorbed through the intestine.

Distribution

After absorption, the calcium first entered the extracellular fluid and then quickly combined into the bone tissue. However, bone formation is not stimulated by using calcium. The bone contains 99% of the body's calcium, the remaining 1% is distributed by the intracellular and extracellular fluid. Calcium concentration in cerebrospinal fluid accounts for about 50% of plasma concentrations in plasma and tend to reflect the calcium concentration in plasma has been ionized. Calcium through the placenta and the concentration of the fetal blood is higher than the mother's blood. Calcium is distributed into breast milk.

Elimination

Calcium is excreted mainly in feces including the amount of calcium that is not absorbed and the amount of calcium is secreted through bile and pancreatic fluid into the gastrointestinal tract. Most of the calcium is filtered through the glomerular reabsorbed in the branches of the Henle straps, the nearby tube and the distance. Only a small amount of calcium cations is eliminated in the urine. Calcium is also eliminated through the sweat gland.

Before taking Calcium Stella 500mg effervescent tablets and support for osteoporosis (20 tablets)

How to use

Calcium Stella 500mg is used by oral. The drug is dissolved in a glass of filtered water (about 200 ml) and drink immediately. The drug can be taken with or outside the meal.

Dosage

Adults and children: 1000 mg/day (2 capsules/day).

Note: The above dose is for reference only. Specific dosage depends on the condition and level of progression of the disease. For a suitable dose, you need to consult a doctor or medical specialist.

What to do when overdose? Symptoms of hypercalcemia include: nausea, vomiting, thirst, drinking plenty of water, multi -uria, dehydration and constipation. Chronic overdose leading to hypercalcemia may cause blood vessel and organs. Calcium poisoning exceeds the threshold of 2000 mg/day, used for months.

Handling

In case of poisoning, should stop using calcium immediately and compensate. In the case of chronic overdose with hypercalcemia, the initial therapeutic step is rehydration with salt solution. After that, diuretics (such as Furosemid) can be used to increase calcium excretion and prevent overload, but should avoid thiazide diuretics.

In patients with renal impairment, rehydration will not be effective and need to be separated. In the case of persistent hypercalcemia, eliminating factors that contribute to increased calcium such as excess vitamin A or D, primary hyperthyroidism, malignant tumor, kidney failure or motionless.

In an emergency, call the 115 emergency center immediately or go to the nearest local health station.

What to do when forgetting a dose? However, if close to the next dose, skip the forgotten dose and take the next dose at the time as planned. Do not drink twice as prescribed.

Side Effects

When using Calcium Stella 500mg, you may experience unwanted effects (ADR).

Less (1/1000

Metabolism and nutrition: hypercalcemia, hypercalciuria.

Rare (1/10000

The immune system: hypersensitivity such as rash, itching, urticaria.

Digestive: flatulence, constipation, diarrhea, nausea, vomiting, abdominal pain.

Very rare (ADR

The immune system: There has been reports on individual cases of allergic reactions (anaphylactic reaction, face edema, nerve angio).

Instructions on how to handle ADR

When experiencing side effects of the drug, it is necessary to stop using and notify the doctor or go to the nearest medical facility for timely treatment.

Warnings

Before using the drug you need to read the instructions carefully and refer to the information below.

Contraindicated

Calcium stella 500mg contraindicated in the following cases:

Hypercalcemia (such as hyperthyroidism, excess vitamin D disorders, bone loss tumors, severe renal failure, metastatic bone cancer), calcium stones due to severe calcium urine hypercalcium and kidney stones.

long -term motional accompanied by hypercalcium and/or hypercalcemia.

Hypersensitivity to any ingredients of the drug.

Precautions when using

must continue to strictly control the excretion of calcium via urinary tract in the event of a slight increase in calcium urinary (exceeding 7.5 mmol/24 hours in adults or 0.12 - 0.15 mmol/kg/24 hours in children) or kidney failure, or evidence that formation of urinary tract stones. If necessary, the dose should be reduced or stop taking calcium. Caution should be used in patients with sarcoid disease due to the ability to increase the metabolism of vitamin D into activity. Serum calcium should be monitored for these patients.

For patients with renal function, when using calcium salts, it is necessary to monitor calcium and phosphate levels in serum.

There has been a report on the increase in aluminum's absorption with Nitrate Calcium Stella 500 mg (containing citric acid), so it is used carefully in patients with severe kidney function, especially in users of aluminum -containing preparations.

Each Calcium Stella 500mg contains about 206.66 mg of sodium.

Powering and operating machinery

Calcium Stella 500mg does not affect the ability to drive and operate machinery.

Pregnancy

The amount of calcium used daily (including food and supplements) to meet the needs of pregnant women and normal breastfeeding is 1000 - 3000 mg. During pregnancy, the amount of calcium used daily should not exceed 1500 mg. Calcium Stella 500 mg effervescent tablet can be used during pregnancy in case of calcium deficiency.

Breastfeeding period

The amount of calcium is significantly secreted in breast milk during breastfeeding but does not cause any unwanted effects for babies. Calcium Stella 500 mg effervescent tablet can be used during breastfeeding in case of calcium deficiency.

Drug interaction

Simultaneously used with vitamin D increases the absorption of calcium and plasma calcium levels can continue to increase after stopping vitamin D.

The effects of digoxin and other cardiac glycosides may increase due to calcium and may cause toxicity.

Calcium salts reduce the absorption of some drugs, especially tetracyclin. Therefore, it is recommended to use calcium away from these preparations at least 2 hours ago or 4 - 6 hours after using calcium.

thiazid diuretics increase the absorption of calcium in the kidneys, so be careful with the risk of hypercalcemia.

bisphosphonate, sodium fluorid: requires a minimum of about 3 hours before taking calcium (risk of reducing the absorption of gastrointestinal tract of bisphosphonate and sodium fluorid).

Corticosteroids use systemic sugar to reduce calcium absorption. Need to increase the dose of calcium stella 500 mg when used simultaneously.

Oxalic acid (found in spinach and royal) and phytic acid (in cereal) can inhibit calcium absorption by forming insoluble compounds with calcium ions. Patients should not use calcium within 2 hours when eating foods rich in oxalic acid and phytic acid.

Storage

In closed packaging, dry place, avoid moisture. The temperature does not exceed 30 ° C.

Expiry date: 24 months from the date of manufacture. Do not use overdue drugs stated on the packaging.

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